Ketoprofen Sf

Ketoprofen, the active ingredient in Ketoprofen Sf, is a Nonsteroidal anti-inflammatory drug (NSAID) presented as an injection for intramuscular use. It treats mild to moderate pain and inflammatory conditions such as rheumatoid arthritis, osteoarthritis, and musculoskeletal injuries in adults. It is indicated for adults requiring rapid analgesia and anti‑inflammatory effect, and is administered by healthcare professionals in clinical settings.

GNH USA supplies Ketoprofen Sf as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide, ensuring quality and regulatory compliance across markets.

Ketoprofen acts as an NSAID to reduce inflammation and pain in musculoskeletal and joint disorders.

Rheumatoid arthritis: reduces joint pain, swelling and stiffness, improving functional ability. Osteoarthritis: alleviates chronic joint discomfort and improves mobility. Musculoskeletal pain and sprains: provides rapid analgesic and anti‑inflammatory relief. Post‑operative pain: helps control moderate pain after surgical procedures.

Ketoprofen may cause a range of adverse reactions, which are categorized by frequency and severity.

Common Side Effects: - Nausea: mild stomach upset may occur. - Dyspepsia: indigestion or heartburn. - Headache: transient headache. - Injection site pain: local discomfort at the administration site.

Serious or Rare Side Effects: - Gastrointestinal ulceration or bleeding. - Renal impairment: reduced kidney function. - Severe hypersensitivity reactions: rash, angioedema, anaphylaxis.

Before prescribing ketoprofen, clinicians should evaluate patient-specific risk factors and monitor therapy appropriately.

- Assess renal function: evaluate baseline kidney function before initiating therapy. - Monitor gastrointestinal risk: consider ulcer prophylaxis in patients with history of GI bleeding. - Avoid in known hypersensitivity: do not use if patient has allergy to ketoprofen or other NSAIDs. - Use caution with anticoagulants: increased bleeding risk when combined with warfarin or similar agents. - Pregnancy and lactation: safety not established; avoid unless benefits outweigh risks. - Store at ambient temperature: keep in original container, protect from moisture and light.

Ketoprofen can interact with several medicines, altering efficacy or safety.

Major Interactions (Avoid): - Concurrent use with anticoagulants (e.g., warfarin): increased risk of serious bleeding. - Combination with other NSAIDs or COX‑2 inhibitors: additive gastrointestinal toxicity. - Use with selective serotonin reuptake inhibitors (SSRIs): heightened bleeding tendency.

Moderate Interactions (Monitor Closely): - Concomitant diuretics or ACE inhibitors: may reduce renal perfusion and function. - Lithium therapy: NSAIDs can raise lithium plasma levels, risking toxicity. - Methotrexate: reduced clearance may increase methotrexate toxicity.