Ketoprofen Ennogen Pharma

Ketoprofen, the active ingredient in Ketoprofen Ennogen Pharma, is a nonsteroidal anti-inflammatory drug (NSAID) presented as an oral tablet for oral use. It treats pain, inflammation and fever in adult patients.

GNH USA supplies Ketoprofen Ennogen Pharma as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Ketoprofen belongs to the NSAID class and is used to manage conditions involving pain and inflammation.

- Pain relief: reduces moderate to severe pain associated with musculoskeletal injuries. - Inflammation reduction: decreases swelling and redness in acute inflammatory states. - Arthritis: alleviates joint pain and stiffness in rheumatoid and osteoarthritis. - Musculoskeletal disorders: improves function and comfort in back pain, tendonitis and sprains.

Ketoprofen may cause a range of adverse reactions, from mild to severe.

Common Side Effects: - Gastrointestinal discomfort: nausea, dyspepsia or abdominal pain. - Headache: mild to moderate intensity. - Dizziness or vertigo. - Skin rash or pruritus. - Mild elevation of liver enzymes. - Fluid retention or mild edema.

Serious or Rare Side Effects: - Gastrointestinal bleeding or ulcer perforation. - Severe renal impairment or acute kidney injury. - Hepatic failure or severe hepatitis. - Stevens‑Johnson syndrome or toxic epidermal necrolysis. - Anaphylactic or severe hypersensitivity reactions. - Cardiovascular events such as myocardial infarction or stroke.

Ketoprofen should be used with careful clinical assessment and monitoring.

- Renal function: evaluate kidney status before initiating therapy and monitor periodically. - Hepatic status: avoid in patients with severe liver disease and monitor liver enzymes. - Cardiovascular risk: use cautiously in patients with existing heart disease or hypertension. - Hypersensitivity: discontinue immediately if allergic reactions to ketoprofen or other NSAIDs occur. - Concomitant anticoagulants: increased risk of bleeding; monitor coagulation parameters. - Store at ambient temperature: keep in the original packaging, protect from moisture and light.

Ketoprofen can interact with several medicines, altering efficacy or safety.

Major Interactions (Avoid): - Anticoagulants (e.g., warfarin): heightened bleeding risk. - ACE inhibitors (e.g., enalapril): possible reduction of antihypertensive effect. - Lithium: increased lithium serum concentrations. - Methotrexate: reduced clearance leading to toxicity. - Loop diuretics (e.g., furosemide): may impair renal function.

Moderate Interactions (Monitor Closely): - SSRIs (e.g., sertraline): additive bleeding tendency. - Corticosteroids: increased risk of gastrointestinal ulceration. - Beta‑blockers: potential attenuation of blood‑pressure control. - Other NSAIDs: additive gastrointestinal and renal toxicity. - Alcohol: enhances gastric irritation and bleeding risk.