Ketonal Rapid

Ketoprofen, the active ingredient in Ketonal Rapid, is a nonsteroidal anti-inflammatory drug (NSAID) presented as an oral tablet for oral use. It treats pain and inflammation in conditions such as rheumatoid arthritis, osteoarthritis and musculoskeletal disorders.

GNH USA supplies Ketonal Rapid as a licensed, GDP-compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Ketoprofen is indicated for inflammatory and painful conditions affecting the musculoskeletal system.

- Rheumatoid arthritis: reduces joint pain, swelling and stiffness. - Osteoarthritis: alleviates chronic joint discomfort and improves mobility. - Musculoskeletal pain: provides relief from acute injuries, strains and sprains. - Acute pain: manages short‑term pain such as postoperative or dental pain.

Ketoprofen may cause a range of adverse reactions, varying from mild to severe.

Common Side Effects: - Gastrointestinal discomfort: nausea, dyspepsia or abdominal pain. - Headache: mild to moderate intensity. - Dizziness or vertigo. - Skin rash: mild erythema or itching.

Serious or Rare Side Effects: - Gastrointestinal ulceration or bleeding. - Severe allergic reactions: anaphylaxis, angioedema. - Renal impairment: sudden decrease in kidney function.

Ketoprofen should be used with caution in several clinical situations.

- Assess gastrointestinal risk: evaluate history of ulcers or bleeding before use. - Monitor renal function: avoid in patients with severe kidney disease. - Use caution in cardiovascular disease: NSAIDs may increase risk of thrombotic events. - Avoid in late pregnancy: NSAIDs are contraindicated in the third trimester. - Review concomitant medications: consider interactions with anticoagulants or antihypertensives. - Store at ambient temperature: keep below 25°C, retain in original packaging and protect from moisture.

Ketoprofen can interact with several drug classes, requiring attention to avoid harmful effects.

Major Interactions (Avoid): - Anticoagulants (e.g., warfarin): increased risk of bleeding. - Other NSAIDs or COX‑2 inhibitors: additive gastrointestinal toxicity. - Corticosteroids: heightened ulcer risk.

Moderate Interactions (Monitor Closely): - ACE inhibitors or ARBs: may reduce renal perfusion, monitor kidney function. - Diuretics: potential for reduced efficacy of antihypertensive effect. - Lithium: NSAIDs can raise lithium serum levels, monitor concentrations.