Ketonal

Ketoprofen, the active ingredient in Ketonal, is a nonsteroidal anti-inflammatory drug (NSAID) presented as an oral tablet for oral use. It is used to relieve pain, reduce inflammation, and manage symptoms of arthritis in adults.

GNH USA supplies Ketonal as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Ketonal is an NSAID that acts on inflammatory pathways to alleviate several musculoskeletal conditions.

Pain: provides analgesic relief for mild to moderate pain. Inflammation: reduces swelling and redness associated with acute inflammatory processes. Arthritis: helps control joint pain and stiffness in osteoarthritis and rheumatoid arthritis.

Ketonal may cause a range of adverse reactions, from mild to severe.

Common Side Effects: - Dyspepsia or stomach upset - Headache - Dizziness - Nausea - Rash or mild skin irritation - Abdominal pain

Serious or Rare Side Effects: - Gastrointestinal ulcer or bleeding - Severe skin reactions such as Stevens‑Johnson syndrome - Hepatotoxicity (liver injury) - Acute kidney injury or worsening renal function - Anaphylactic reactions - Increased risk of cardiovascular events such as myocardial infarction

Before prescribing Ketonal, clinicians should consider several safety measures.

Assess renal function: evaluate kidney health prior to initiation. Monitor gastrointestinal risk: review history of ulcers or bleeding. Avoid in known hypersensitivity: discontinue if allergic signs appear. Use caution with anticoagulants: heightened bleeding potential. Limit use in cardiovascular disease: weigh risk‑benefit carefully. Store at ambient temperature: keep in original pack, protect from moisture.

Ketonal can interact with other medicines, requiring attention to avoid adverse outcomes.

Major Interactions (Avoid): - Anticoagulants (e.g., warfarin): increased bleeding risk. - Other NSAIDs or aspirin: additive gastrointestinal toxicity. - SSRIs: heightened bleeding tendency. - Corticosteroids: increased ulcer risk. - Lithium: reduced clearance, potential toxicity.

Moderate Interactions (Monitor Closely): - ACE inhibitors: possible alteration of renal function. - Diuretics: may affect renal handling and efficacy. - Methotrexate: decreased excretion, risk of toxicity. - Cyclosporine: increased nephrotoxicity. - Beta‑blockers: possible impact on blood pressure control.