Ketonal

Ketoprofen, the active ingredient in Ketonal, is a nonsteroidal anti-inflammatory drug presented as an oral formulation for systemic use. It is employed to relieve pain and inflammation associated with musculoskeletal conditions, arthritis and postoperative recovery in adult patients. GNH USA supplies Ketonal as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Ketoprofen acts as an NSAID to manage pain and inflammatory disorders. - Rheumatoid arthritis: reduces joint pain, swelling and stiffness. - Osteoarthritis: alleviates chronic joint discomfort and improves mobility. - Musculoskeletal injuries: diminishes pain, inflammation and edema after sprains or strains. - Post‑operative pain: provides analgesic relief during the early recovery period.

Ketoprofen may cause a range of adverse reactions, from mild to severe.

Common Side Effects: - Gastrointestinal discomfort: nausea, dyspepsia or abdominal pain. - Headache or dizziness. - Mild skin rash or pruritus. - Elevated blood pressure in susceptible individuals.

Serious or Rare Side Effects: - Peptic ulcer disease or gastrointestinal bleeding. - Renal impairment or acute kidney injury. - Hepatotoxicity presenting as jaundice or abnormal liver enzymes. - Severe hypersensitivity reactions such as Stevens‑Johnson syndrome. - Cardiovascular events including myocardial infarction or stroke.

When using Ketoprofen, consider the following safety measures. - Gastrointestinal risk: assess history of ulcers or bleeding before initiating therapy. - Renal function: monitor kidney parameters in patients with pre‑existing renal disease. - Cardiovascular health: use cautiously in individuals with hypertension or heart disease. - Concomitant drugs: avoid simultaneous use with other NSAIDs or anticoagulants without medical guidance. - Pregnancy and lactation: discuss risks with a healthcare professional before use. - Store at ambient temperature: keep below 25 °C, retain in original packaging and protect from moisture.

Ketoprofen can interact with several medication classes, requiring attention to dosage and monitoring.

Major Interactions (Avoid): - Anticoagulants (e.g., warfarin): increased risk of serious bleeding. - Other NSAIDs or COX‑2 inhibitors: heightened gastrointestinal toxicity. - Selective serotonin reuptake inhibitors (SSRIs): additive bleeding risk.

Moderate Interactions (Monitor Closely): - ACE inhibitors or diuretics: possible reduction in renal function. - Lithium: NSAIDs may raise lithium serum levels. - Methotrexate: decreased clearance leading to toxicity.