Ketonal

Ketoprofen, the active ingredient in Ketonal, is a nonsteroidal anti-inflammatory drug presented as an oral dosage form for oral use. It treats pain and inflammation in adults, including musculoskeletal and joint conditions. GNH USA supplies Ketonal as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Ketonal is an NSAID that reduces inflammation and pain in several musculoskeletal and inflammatory disorders. - Pain: provides relief from acute and chronic pain conditions. - Rheumatoid arthritis: decreases joint inflammation and stiffness. - Osteoarthritis: improves mobility and reduces joint discomfort. - Dysmenorrhea: alleviates menstrual cramps. - Musculoskeletal pain: eases strain‑related discomfort.

Ketonal may cause a range of adverse reactions, from mild to severe.

Common Side Effects: - Gastrointestinal upset: nausea, dyspepsia, or abdominal discomfort. - Headache: mild to moderate intensity. - Dizziness or vertigo. - Skin rash: mild erythema or itching. - Elevated blood pressure. - Mild renal function changes.

Serious or Rare Side Effects: - Gastrointestinal bleeding or ulcer perforation. - Severe liver injury or hepatitis. - Stevens‑Johnson syndrome or toxic epidermal necrolysis. - Anaphylactic reaction. - Acute renal failure. - Cardiovascular thrombotic events.

Before prescribing Ketonal, clinicians should consider several safety measures. - Assess gastrointestinal risk: avoid in patients with a history of ulcers or bleeding. - Monitor renal function: use caution in those with impaired kidney function. - Evaluate cardiovascular risk: consider alternatives for patients with heart disease. - Avoid use in known hypersensitivity to ketoprofen or other NSAIDs. - Use the lowest effective dose for the shortest duration needed. - Store at room temperature: keep in the original pack, protect from moisture.

Ketonal can interact with other medicines, requiring careful management.

Major Interactions (Avoid): - Anticoagulants (e.g., warfarin): increased bleeding risk. - Selective serotonin reuptake inhibitors (SSRIs): heightened gastrointestinal bleeding. - Lithium: elevated lithium serum levels.

Moderate Interactions (Monitor Closely): - Other NSAIDs or aspirin: additive gastrointestinal toxicity. - Corticosteroids: increased ulcer risk. - Methotrexate: reduced clearance leading to toxicity. - Antihypertensives (e.g., ACE inhibitors, diuretics): possible renal function decline. - Oral hypoglycemics: potential alteration of blood glucose control.