GNH USA

Europe — EMA

Ketonal

GNH USA supplies Ketonal (Ketoprofen), a nonsteroidal anti-inflammatory drug for pain, inflammation and arthritis. Request a quote for global supply.

Ketoprofen

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What is Ketoprofen?

Ketoprofen, the active ingredient in Ketonal, is a nonsteroidal anti-inflammatory drug (NSAID) presented as an oral tablet for oral use. It treats musculoskeletal pain, dental pain, postoperative discomfort and inflammatory joint conditions in adults. GNH USA supplies Ketonal as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

What is Ketoprofen used for?

Ketonal, an NSAID, is employed to manage pain and inflammation across several clinical settings. - Musculoskeletal pain: reduces pain and swelling associated with strains, sprains and osteoarthritis. - Dental pain: alleviates postoperative dental discomfort and inflammatory oral conditions. - Post‑surgical pain: provides analgesia after minor surgical procedures. - Arthritis: helps control chronic joint inflammation and stiffness in rheumatoid and osteoarthritis.

What are the side effects of Ketoprofen?

Ketonal may cause a range of adverse reactions, from mild to severe.

Common Side Effects: - Gastrointestinal upset: nausea, dyspepsia or abdominal discomfort. - Headache or dizziness. - Skin rash or mild itching.

Serious or Rare Side Effects: - Gastrointestinal bleeding or ulcer perforation. - Acute renal impairment or worsening of chronic kidney disease. - Severe hypersensitivity reactions, including anaphylaxis or Stevens‑Johnson syndrome.

What precautions apply to Ketoprofen?

Before prescribing Ketonal, clinicians should evaluate patient‑specific risk factors and monitor therapy closely. - Assess gastrointestinal risk: avoid in patients with active ulcers or a history of GI bleeding. - Monitor renal function: use caution in those with impaired kidney function. - Use the lowest effective dose for the shortest duration needed. - Avoid in individuals with known hypersensitivity to ketoprofen or other NSAIDs. - Caution when combined with anticoagulants or antiplatelet agents. - Store at ambient temperature: keep in the original container, protect from moisture and heat.

What does Ketoprofen interact with?

Ketonal can interact with several drug classes, requiring careful management.

Major Interactions (Avoid): - Anticoagulants (e.g., warfarin): increased risk of bleeding. - Other NSAIDs or aspirin: additive gastrointestinal toxicity. - Lithium: elevated lithium serum concentrations.

Moderate Interactions (Monitor Closely): - Diuretics and ACE inhibitors: possible reduction in renal perfusion. - Selective serotonin reuptake inhibitors (SSRIs): heightened bleeding tendency.

Frequently asked questions

What conditions is Ketonal used for?+
Ketonal, containing ketoprofen, is indicated for the relief of mild to moderate musculoskeletal pain, dental pain, postoperative discomfort, and the management of inflammatory joint disorders such as osteoarthritis and rheumatoid arthritis.
How does ketoprofen work to relieve pain?+
Ketoprofen works by inhibiting the cyclooxygenase enzymes COX‑1 and COX‑2, which reduces the production of prostaglandins. Lower prostaglandin levels decrease inflammation and the sensitisation of pain receptors, resulting in analgesic and anti‑inflammatory effects.
What is the usual dose of Ketonal?+
The appropriate dose of Ketonal is determined by the prescribing healthcare professional based on the individual’s condition, age, renal function and other clinical factors. Patients should follow the prescriber’s instructions and not adjust the dose on their own.
Is Ketonal safe to use during pregnancy or breastfeeding?+
Ketonal is generally not recommended during pregnancy, especially in the third trimester, because NSAIDs may affect fetal cardiovascular function. It should also be used with caution while breastfeeding, as ketoprofen can be excreted in breast milk. Consultation with a healthcare provider is essential.
How do I order Ketonal from GNH USA?+
To order Ketonal, submit an enquiry on the product page at gnh-usa.com, specifying the required quantity. GNH USA works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.
How does Ketonal compare with other NSAIDs?+
Ketonal (ketoprofen) offers analgesic and anti‑inflammatory potency comparable to ibuprofen and naproxen, but it may have a slightly higher risk of gastrointestinal irritation. Choice of NSAID often depends on individual tolerability, specific clinical indications and physician preference.
What are the recommended storage conditions for Ketonal?+
Ketonal should be stored at ambient temperature, below 25 °C. Keep the tablets in the original packaging, protect them from moisture and direct sunlight, and ensure they are out of reach of children.
How is Ketonal administered?+
Ketonal is taken orally, usually with a full glass of water. It can be taken with or without food, although taking it with meals may reduce gastrointestinal discomfort. Swallow tablets whole; do not crush or chew them.
What are the most serious risks associated with Ketonal?+
The most serious risks include gastrointestinal bleeding or ulcer perforation, severe allergic reactions such as anaphylaxis or Stevens‑Johnson syndrome, and acute kidney injury, particularly in patients with pre‑existing renal impairment or dehydration.
Who should not use Ketonal?+
Ketonal should be avoided in individuals with known hypersensitivity to ketoprofen or other NSAIDs, active gastrointestinal ulcer disease, severe heart failure, uncontrolled hypertension, and in patients who are in the third trimester of pregnancy.
Information provided on this page is for educational use by procurement and clinical professionals. Always consult a licensed healthcare provider for medical advice and prescribing decisions. GNH USA supplies this product subject to applicable regulatory and licensing requirements.

Product details

Drug
Ketoprofen
Route
Oral Use
Manufacturer
Sandoz D.O.O.
Origin
EU

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