Ketonal

Ketoprofen, the active ingredient in Ketonal, is a nonsteroidal anti-inflammatory drug presented as an injectable solution for intramuscular and intravenous use. It provides analgesic and anti‑inflammatory effects for pain, rheumatoid arthritis, osteoarthritis and other musculoskeletal disorders in adult patients, suitable for both acute and chronic management.

GNH USA supplies Ketonal as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide, ensuring quality and regulatory conformity across EU and global markets, with a focus on consistent potency and safety.

Ketonal (ketoprofen) is used to manage inflammatory and painful conditions affecting the musculoskeletal system.

- Pain: reduces moderate to severe pain associated with injury or disease. - Rheumatoid arthritis: alleviates joint inflammation and pain. - Osteoarthritis: improves mobility and lessens chronic joint discomfort. - Musculoskeletal disorders: controls swelling and inflammation after trauma. - Post‑operative pain: provides short‑term analgesia following surgical procedures.

Ketonal may cause a range of adverse reactions.

Common Side Effects: - Nausea: mild stomach upset may occur. - Dyspepsia: indigestion or heartburn. - Headache: transient head discomfort. - Injection site pain: local discomfort after IM/IV administration.

Serious or Rare Side Effects: - Gastrointestinal bleeding: risk of serious bleeding in stomach or intestines. - Renal impairment: reduced kidney function, especially with prolonged use. - Severe allergic reaction: rash, swelling, or anaphylaxis. - Hepatic dysfunction: elevated liver enzymes or hepatitis.

When using Ketonal, consider the following precautions.

- Assess renal function: check kidney status before initiating therapy, especially in elderly or dehydrated patients. - Monitor gastrointestinal risk: avoid in patients with a history of ulcers or bleeding. - Use lowest effective dose: limit duration to reduce adverse event risk. - Caution in cardiovascular disease: NSAIDs may increase risk of thrombotic events. - Avoid concurrent anticoagulants: increased bleeding risk when combined with warfarin or similar agents. - Store at ambient temperature: keep below 25°C in original packaging, protect from moisture and light.

Ketonal can interact with several medicines.

Major Interactions (Avoid): - Anticoagulants (e.g., warfarin): heightened bleeding risk. - Other NSAIDs or aspirin: additive gastrointestinal toxicity. - Corticosteroids: increased ulcer risk.

Moderate Interactions (Monitor Closely): - Lithium: NSAIDs can raise lithium serum levels. - Methotrexate: reduced clearance may cause toxicity. - SSRIs: modest increase in bleeding tendency.