Ketonal

Ketoprofen, the active ingredient in Ketonal, is a nonsteroidal anti-inflammatory drug (NSAID) presented as a topical formulation for skin application. It treats local musculoskeletal pain, osteoarthritis, rheumatoid arthritis and soft‑tissue injuries in adults.

GNH USA supplies Ketonal as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Ketoprofen acts on inflammatory pathways associated with musculoskeletal disorders, providing relief in several conditions.

- Musculoskeletal pain: reduces localized pain and inflammation in muscles and joints. - Osteoarthritis: alleviates joint discomfort and improves mobility. - Rheumatoid arthritis: helps control inflammatory symptoms in affected joints. - Soft‑tissue injuries: diminishes pain and swelling from sprains, strains and bruises.

Topical ketoprofen may cause skin‑related reactions and, in rare cases, systemic adverse events.

Common Side Effects: - Skin irritation: redness, burning or itching at the application site. - Dryness: localized skin dryness or flaking. - Pruritus: mild itching after application.

Serious or Rare Side Effects: - Severe skin reactions: Stevens‑Johnson syndrome or toxic epidermal necrolysis. - Allergic response: swelling, hives or angioedema. - Systemic effects: gastrointestinal bleeding, renal impairment or hepatic injury.

Before using Ketonal, consider the following precautions.

- Assess medical history: evaluate for NSAID hypersensitivity or previous adverse reactions. - Avoid broken skin: do not apply on open wounds, cuts or infected areas. - Limit duration: use only for the period recommended by the prescriber. - Monitor gastrointestinal symptoms: watch for signs of ulcer or bleeding. - Caution in renal or hepatic disease: adjust use under medical supervision. - Store at ambient temperature: keep below 25 °C in the original packaging, protected from moisture and heat.

Ketonal can interact with other medicines; some combinations should be avoided while others require monitoring.

Major Interactions (Avoid): - Anticoagulants (e.g., warfarin): increased risk of bleeding. - Other NSAIDs or aspirin: additive gastrointestinal toxicity. - Lithium: heightened lithium serum levels.

Moderate Interactions (Monitor Closely): - Diuretics: possible reduction in renal function. - ACE inhibitors or ARBs: potential for reduced renal perfusion. - Selective serotonin reuptake inhibitors (SSRIs): increased bleeding risk.