Ketonal

Ketoprofen, the active ingredient in Ketonal, is a nonsteroidal anti-inflammatory drug (NSAID) presented as a topical formulation for skin application. It reduces pain and inflammation associated with musculoskeletal disorders and is used in adults who need localized relief.

GNH USA supplies Ketonal as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Ketonal, a topical NSAID, is applied to conditions involving inflammation and pain in the musculoskeletal system. - Osteoarthritis: eases joint pain and improves mobility. - Rheumatoid arthritis: diminishes joint swelling and discomfort. - Acute musculoskeletal pain: provides rapid localized pain relief. - Soft‑tissue injuries (sprains, strains, tendinitis): reduces inflammation and supports functional recovery.

Ketonal may cause a range of adverse reactions, most of which are mild and reversible.

Common Side Effects: - Skin irritation at the application site. - Redness or erythema. - Itching or mild rash. - Dryness of the treated area. - Burning sensation. - Localized swelling.

Serious or Rare Side Effects: - Severe allergic reaction (anaphylaxis) with difficulty breathing. - Stevens‑Johnson syndrome or toxic epidermal necrolysis. - Significant skin ulceration or necrosis. - Systemic NSAID toxicity (e.g., gastrointestinal bleeding) if absorbed in large amounts. - Renal impairment in susceptible individuals. - Cardiovascular events such as myocardial infarction or stroke.

Before using Ketonal, consider the following safety measures. - Contraindications: Do not use in patients with known hypersensitivity to ketoprofen or other NSAIDs. - Gastrointestinal risk: Avoid in individuals with active peptic ulcer disease or recent GI bleeding. - Cardiovascular caution: Use cautiously in patients with a history of heart disease or hypertension. - Renal and hepatic function: Monitor patients with impaired kidney or liver function. - Pregnancy and lactation: Discuss risks with a healthcare professional before use. - Store below 25°C: keep in the original packaging, protect from moisture and heat.

Ketonal can affect the safety or efficacy of several other medicines.

Major Interactions (Avoid): - Anticoagulants (e.g., warfarin): increased risk of serious bleeding. - Other NSAIDs or COX‑2 inhibitors: heightened gastrointestinal and renal toxicity. - High‑dose aspirin: additive platelet inhibition leading to bleeding.

Moderate Interactions (Monitor Closely): - ACE inhibitors or ARBs: may reduce renal function, especially in dehydrated patients. - Diuretics: potential for reduced kidney perfusion. - Lithium: NSAIDs can raise lithium serum levels, requiring monitoring.