GNH USA

Europe — EMA

Ketonal Intensive

GNH USA supplies Ketonal Intensive (Ketoprofen Lysine), an NSAID for mild to moderate pain, musculoskeletal and dental pain.

Ketoprofen Lysine

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What is Ketoprofen Lysine?

Ketoprofen Lysine, the active ingredient in Ketonal Intensive, is a nonsteroidal anti-inflammatory drug (NSAID) presented as an oral tablet for systemic use. It is employed to relieve mild to moderate pain and to reduce inflammation in conditions such as musculoskeletal disorders, rheumatoid arthritis, osteoarthritis, and dental pain.

GNH USA supplies Ketonal Intensive as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide. The company adheres to stringent quality standards and provides reliable logistics for global distribution across multiple regulatory jurisdictions.

What is Ketoprofen Lysine used for?

Ketoprofen Lysine is indicated for several painful and inflammatory conditions affecting the musculoskeletal and dental systems.

Mild to moderate pain: provides analgesic relief for temporary discomfort such as headaches or minor injuries. Musculoskeletal pain: reduces inflammation and pain associated with strains, sprains, and backache. Rheumatoid arthritis: helps control joint inflammation and stiffness in chronic autoimmune disease. Osteoarthritis: alleviates pain and improves joint function in degenerative joint disease. Dental pain: diminishes postoperative or inflammatory pain following dental procedures.

What are the side effects of Ketoprofen Lysine?

Ketoprofen Lysine may cause a range of adverse reactions, varying from mild to serious.

Common Side Effects: - Gastrointestinal discomfort: nausea, dyspepsia, or abdominal pain. - Headache: mild to moderate intensity. - Dizziness: transient vertigo or light‑headedness.

Serious or Rare Side Effects: - Gastrointestinal ulcer or bleeding: potentially life‑threatening hemorrhage. - Hepatic injury: elevated liver enzymes or hepatitis. - Severe skin reactions: Stevens‑Johnson syndrome, toxic epidermal necrolysis, or anaphylaxis.

What precautions apply to Ketoprofen Lysine?

When prescribing Ketoprofen Lysine, clinicians should consider several safety precautions to minimise risk.

- Assess renal function: evaluate kidney health before initiating therapy, especially in elderly patients. - Monitor hepatic status: check liver enzymes periodically in patients with pre‑existing liver disease. - Evaluate cardiovascular risk: use cautiously in individuals with history of heart disease or hypertension. - Review gastrointestinal history: avoid in patients with active ulcers or prior gastrointestinal bleeding. - Avoid concurrent NSAIDs: do not combine with other non‑steroidal anti‑inflammatory drugs to reduce additive toxicity. - Store at ambient temperature: keep below 25 °C in the original packaging, protected from moisture and direct sunlight.

What does Ketoprofen Lysine interact with?

Ketoprofen Lysine can interact with other medicines, altering efficacy or safety.

Major Interactions (Avoid): - Anticoagulants (e.g., warfarin): increased risk of serious bleeding. - Selective COX‑2 inhibitors: additive gastrointestinal toxicity.

Moderate Interactions (Monitor Closely): - ACE inhibitors or ARBs: may reduce renal function when combined. - Diuretics: heightened risk of renal impairment and electrolyte imbalance. - Lithium: NSAIDs can raise lithium serum levels, risking toxicity.

Frequently asked questions

What conditions is Ketonal Intensive used to treat?+
Ketonal Intensive, containing ketoprofen lysine, is prescribed for mild to moderate pain, musculoskeletal discomfort, rheumatoid arthritis, osteoarthritis, and dental pain. It helps reduce inflammation and provides analgesic relief in these recognized therapeutic areas.
How does ketoprofen lysine work to relieve pain?+
Ketoprofen lysine works by reversibly inhibiting the cyclooxygenase‑1 and cyclooxygenase‑2 enzymes. This blocks prostaglandin production, which lowers inflammation and peripheral sensitisation, resulting in reduced pain perception.
What determines the dose of Ketonal Intensive?+
The appropriate dose of Ketonal Intensive is determined by the prescribing clinician based on the patient’s condition, severity of symptoms, age, renal and hepatic function, and any concomitant medications. No fixed regimen is provided here.
Is Ketonal Intensive safe to use during pregnancy or while breastfeeding?+
Safety data for ketoprofen lysine in pregnancy and lactation are limited. It should only be used if the potential benefit justifies the potential risk to the fetus or infant, and only under medical supervision.
How do I order Ketonal Intensive from GNH USA?+
To order Ketonal Intensive, submit an enquiry on the product page at gnh-usa.com specifying the required quantity. GNH USA works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.
How does Ketonal Intensive compare with other NSAIDs such as ibuprofen?+
Ketonal Intensive (ketoprofen lysine) and ibuprofen belong to the same NSAID class but differ in potency and pharmacokinetics. Ketoprofen often provides stronger analgesia at lower doses, while ibuprofen is widely used for milder pain. Both share similar gastrointestinal and cardiovascular risk profiles, so choice depends on clinical judgement and patient tolerance.
What are the recommended storage conditions for Ketonal Intensive?+
Ketonal Intensive should be stored at ambient temperature, preferably below 25 °C. Keep the tablets in the original blister pack, protect them from moisture, heat and direct sunlight to maintain stability.
How is Ketonal Intensive administered?+
Ketonal Intensive is taken orally as a tablet with a full glass of water. It may be taken with or without food, although taking it with meals can reduce the likelihood of gastrointestinal discomfort.
What are the most serious risks to watch for while using Ketonal Intensive?+
Serious risks include gastrointestinal ulceration or bleeding, severe liver injury, acute kidney impairment, cardiovascular events such as myocardial infarction or stroke, and rare but life‑threatening skin reactions like Stevens‑Johnson syndrome. Patients should seek immediate medical attention if they experience signs of these conditions.
Who should not use Ketonal Intensive?+
Ketonal Intensive should be avoided in individuals with known hypersensitivity to ketoprofen or other NSAIDs, active gastrointestinal ulcer or bleeding, severe renal or hepatic impairment, uncontrolled hypertension, and in patients who have had recent coronary artery bypass surgery or other major cardiovascular events.
Information provided on this page is for educational use by procurement and clinical professionals. Always consult a licensed healthcare provider for medical advice and prescribing decisions. GNH USA supplies this product subject to applicable regulatory and licensing requirements.

Product details

Drug
Ketoprofen Lysine
Route
Oral Use
Manufacturer
Sandoz Pharmaceuticals D.D.
Origin
EU

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