Ketonal Forte Sr

Ketoprofen, the active ingredient in Ketonal Forte Sr, is a nonsteroidal anti-inflammatory drug (NSAID) presented as an oral tablet for systemic use. It is employed to relieve mild to moderate pain and to reduce inflammation in musculoskeletal disorders such as osteoarthritis and rheumatoid arthritis.

GNH USA supplies Ketonal Forte Sr as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Ketoprofen acts as an NSAID that reduces inflammation and pain in several musculoskeletal conditions. - Mild to moderate pain: provides analgesic relief for acute or chronic pain episodes. - Osteoarthritis: diminishes joint pain and improves functional mobility. - Rheumatoid arthritis: helps control inflammatory joint swelling and stiffness. - Inflammatory musculoskeletal conditions: reduces swelling and discomfort in tendonitis, bursitis and similar disorders.

Ketoprofen may cause a range of adverse reactions, from mild to serious.

Common Side Effects: - Gastrointestinal discomfort or dyspepsia - Headache - Dizziness - Skin rash or pruritus - Mild elevation of liver enzymes

Serious or Rare Side Effects: - Gastrointestinal ulceration or bleeding - Acute renal impairment or failure - Severe skin reactions such as Stevens‑Johnson syndrome - Hepatotoxicity with marked enzyme elevation - Anaphylactic or anaphylactoid reactions

Before initiating therapy, consider the following safety measures. - Assess renal function: adjust or avoid use in patients with significant renal impairment. - Monitor gastrointestinal risk: avoid in individuals with a history of ulcer or bleeding. - Avoid concomitant anticoagulants: increased risk of hemorrhage. - Use caution in cardiovascular disease: NSAIDs may elevate cardiovascular event risk. - Pregnancy and lactation: consult a healthcare professional before use. - Store at ambient temperature: keep in the original pack, protect from moisture.

Ketoprofen can interact with several drug classes, requiring careful management.

Major Interactions (Avoid): - Anticoagulants (e.g., warfarin): heightened bleeding risk. - Other NSAIDs or COX‑2 inhibitors: additive gastrointestinal toxicity. - Selective serotonin reuptake inhibitors (SSRIs): increased bleeding potential. - ACE inhibitors or diuretics: may impair renal function. - Lithium: can raise serum lithium concentrations.

Moderate Interactions (Monitor Closely): - Corticosteroids: synergistic ulcer risk. - Methotrexate: reduced clearance, possible toxicity. - Cyclosporine: enhanced nephrotoxic effect. - Diabetes medications: possible alteration of glycemic control. - Diuretics: potential electrolyte disturbances.