GNH USA

Europe — EMA

Ketokonazol Pinewood Laboratories

GNH USA supplies Ketokonazol Pinewood Laboratories (Ketoconazole), an imidazole antifungal for tinea infections and seborrheic dermatitis.

Ketoconazole

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What is Ketoconazole?

Ketoconazole, the active ingredient in Ketokonazol Pinewood Laboratories, is an imidazole antifungal presented as a topical formulation for skin application. It is used to treat fungal skin infections such as athlete’s foot, ringworm and seborrheic dermatitis in adult and pediatric patients. The medication works by inhibiting fungal cell‑membrane synthesis, helping to clear infection and reduce associated symptoms.

GNH USA supplies Ketokonazol Pinewood Laboratories as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

What is Ketoconazole used for?

Ketoconazole is an imidazole antifungal indicated for superficial fungal skin conditions.

- Tinea corporis: reduces fungal growth and promotes healing of ringworm lesions. - Tinea cruris: alleviates itching and clears fungal infection in the groin area. - Tinea pedis: treats athlete’s foot by eliminating dermatophytes on the feet. - Seborrheic dermatitis: controls Malassezia overgrowth and reduces scalp flaking. - Pityriasis versicolor: restores normal skin pigmentation by eradicating yeast infection.

What are the side effects of Ketoconazole?

Ketoconazole topical preparations may cause local skin reactions.

Common Side Effects: - Burning or stinging sensation at the application site. - Itching or pruritus. - Redness or erythema. - Dryness or peeling of the skin.

Serious or Rare Side Effects: - Severe allergic reaction (e.g., angioedema, anaphylaxis). - Extensive skin rash or dermatitis. - Stevens‑Johnson syndrome or toxic epidermal necrolysis. - Hepatic toxicity (rare with extensive topical use).

What precautions apply to Ketoconazole?

When using Ketokonazol, consider the following safety measures.

- Avoid use on broken skin: may increase irritation and systemic absorption. - Do not apply to eyes, mucous membranes, or genital mucosa: risk of severe local irritation. - Limit application to small body areas: extensive use can raise systemic exposure. - Discontinue if severe irritation or allergic reaction occurs: seek medical advice. - Store at room temperature: keep in the original container, protect from moisture and light.

What does Ketoconazole interact with?

Ketokonazol may interact with other medications or substances.

Major Interactions (Avoid): - Concurrent systemic azole antifungals: may increase overall azole exposure and toxicity. - Use with potent topical corticosteroids: can mask infection signs and delay healing.

Moderate Interactions (Monitor Closely): - Alcohol consumption: may exacerbate skin irritation. - Other topical irritants (e.g., retinoids, exfoliants): may increase local adverse reactions. - Phototherapy or UV exposure: may heighten photosensitivity of treated skin.

Frequently asked questions

What conditions is Ketokonazol used for?+
Ketokonazol contains ketoconazole, an imidazole antifungal indicated for superficial fungal skin infections such as tinea corporis (ringworm), tinea cruris (jock itch), tinea pedis (athlete’s foot), seborrheic dermatitis, and pityriasis versicolor. It is applied topically to the affected skin areas to reduce fungal growth and improve symptoms.
How does ketoconazole work against fungal infections?+
Ketoconazole blocks the fungal enzyme lanosterol 14α‑demethylase, which is essential for synthesising ergosterol, a key component of the fungal cell membrane. Inhibiting ergosterol production compromises membrane integrity, leading to increased permeability, disrupted cellular processes, and ultimately fungal cell death.
What is the usual dose of Ketokonazol?+
The specific dosage and frequency of Ketokonazol are determined by the prescribing healthcare professional based on the infection type, severity, patient age, and treatment guidelines. Patients should follow the prescriber’s instructions and the product label for proper application.
Is Ketokonazol safe to use during pregnancy or breastfeeding?+
Safety data for topical ketoconazole in pregnancy and lactation are limited. Healthcare providers should evaluate the potential benefits against any possible risks before prescribing to pregnant or nursing individuals. Women should discuss their situation with a qualified clinician.
How do I order Ketokonazol from GNH USA?+
To place an order, submit an enquiry on the product page at gnh-usa.com, specifying the required quantity. GNH USA works with hospitals, pharmacies, and procurement teams worldwide, confirming trade or institutional credentials before providing pricing, availability, shipping details (including any cold‑chain requirements), and necessary import documentation.
How does Ketokonazol compare with other antifungal options?+
Ketokonazol is an imidazole antifungal, offering broad‑spectrum activity against dermatophytes and yeasts. Compared with allylamine agents such as terbinafine, ketoconazole has a slightly different mechanism and may be preferred for certain yeast‑driven conditions like seborrheic dermatitis. Choice of therapy depends on infection type, patient factors, and clinician preference.
What are the storage and handling requirements for Ketokonazol?+
Ketokonazol should be stored at room temperature, below 25 °C, in its original packaging. Keep the container tightly closed, protect it from moisture and direct sunlight, and ensure it is out of reach of children.
How is Ketokonazol applied?+
Ketokonazol is applied topically to clean, dry skin. A thin layer is spread over the affected area, usually once or twice daily as directed by the prescriber. Hands should be washed after application, and the treated skin should not be covered with occlusive dressings unless advised.
What are the most serious risks associated with Ketokonazol?+
Serious risks, though rare, include severe allergic reactions such as angioedema, anaphylaxis, extensive skin rash, Stevens‑Johnson syndrome, toxic epidermal necrolysis, and, with extensive use, possible hepatic toxicity. Patients should stop treatment and seek immediate medical attention if they notice any of these severe symptoms.
Who should not use Ketokonazol?+
Ketokonazol should be avoided in individuals with known hypersensitivity to ketoconazole or any component of the formulation. It is also contraindicated on broken skin, mucous membranes, or the eyes, and should not be used in patients who have experienced severe cutaneous adverse reactions to azole antifungals.
Information provided on this page is for educational use by procurement and clinical professionals. Always consult a licensed healthcare provider for medical advice and prescribing decisions. GNH USA supplies this product subject to applicable regulatory and licensing requirements.

Product details

Drug
Ketoconazole
Route
Cutaneous Use
Manufacturer
Pinewood Laboratories Limited
Origin
EU

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