Ketoftil

Ketotifen hydrogen fumarate, the active ingredient in Ketoftil, is an antihistamine (mast cell stabilizer) presented as an ophthalmic solution for ocular use. It is employed to relieve symptoms of allergic eye conditions such as conjunctivitis, seasonal allergic eye disease, and ocular itching in patients of all ages. GNH USA supplies Ketoftil as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Ketoftil acts on allergic ocular inflammation and provides symptomatic relief for several eye conditions.

Allergic conjunctivitis: reduces itching, redness and watery discharge caused by allergens. Seasonal allergic eye disease: stabilises mast cells to prevent flare‑ups during pollen seasons. Ocular itching: alleviates persistent itch associated with allergic reactions.

Ketoftil may cause local and systemic adverse reactions.

Common Side Effects: - Stinging or burning sensation upon instillation. - Transient blurred vision. - Mild eye irritation or redness. - Temporary headache. - Dry eye sensation. - Mild eyelid swelling.

Serious or Rare Side Effects: - Severe allergic reaction (anaphylaxis) with swelling of the face or throat. - Corneal ulceration or persistent epithelial defect. - Significant visual loss or sudden decrease in vision. - Persistent eye pain unresponsive to treatment. - Secondary ocular infection.

Before using Ketoftil, consider the following precautions. - Hypersensitivity: avoid if the patient has known allergy to ketotifen or formulation excipients. - Contact lens wear: discontinue use while wearing lenses and wait at least 15 minutes after instillation before reinserting. - Ocular infection: monitor for signs of infection; discontinue if infection develops. - Dry eye syndrome: use with caution in patients with severe dry eye, as irritation may worsen. - Store at room temperature: keep in the original container, protect from light and moisture.

Ketoftil may interact with other ophthalmic or systemic agents.

Major Interactions (Avoid): - Concurrent use of multiple ocular antihistamines may increase local irritation. - Combination with topical corticosteroids may mask signs of infection.

Moderate Interactions (Monitor Closely): - Systemic antihistamines may enhance sedative effects. - Co‑administration with beta‑blocker eye drops may affect intra‑ocular pressure control. - Preservative‑containing contact lens solutions may exacerbate ocular irritation.