Europe — EMA
Ketodex Forte (Dexketoprofen)
GNH USA supplies Ketodex Forte (Dexketoprofen), a nonsteroidal anti-inflammatory drug for acute, post‑operative and musculoskeletal pain.
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What is Dexketoprofen?
Dexketoprofen, the active ingredient in Ketodex Forte, is a Nonsteroidal anti-inflammatory drug (NSAID) presented as an injectable solution for intramuscular and intravenous use. It is employed to treat acute pain, post‑operative pain and musculoskeletal pain in adult patients.
GNH USA supplies Ketodex Forte as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.
What is Dexketoprofen used for?
Dexketoprofen, an NSAID, is indicated for conditions that involve acute nociceptive pain.
Acute pain: provides rapid analgesia for severe short‑term pain episodes. Post‑operative pain: reduces discomfort following surgical procedures. Musculoskeletal pain: alleviates pain associated with injuries or inflammatory musculoskeletal conditions.
What are the side effects of Dexketoprofen?
Adverse reactions may occur with Dexketoprofen use.
Common Side Effects: - Nausea - Dyspepsia - Headache - Dizziness - Injection‑site pain or erythema - Transient increase in blood pressure
Serious or Rare Side Effects: - Gastrointestinal bleeding or ulceration - Severe cutaneous reactions such as Stevens‑Johnson syndrome - Acute renal impairment - Hepatic dysfunction - Anaphylactic or severe hypersensitivity reactions - Thrombotic cardiovascular events
What precautions apply to Dexketoprofen?
When prescribing Dexketoprofen, clinicians should consider several safety aspects.
Renal function: assess before use in patients with renal impairment. Gastrointestinal risk: avoid in individuals with active ulcer disease or a history of GI bleeding. Cardiovascular risk: use cautiously in patients with prior thrombotic events. Bleeding risk: monitor closely when combined with anticoagulants or antiplatelet agents. Pregnancy and lactation: limit use to situations where benefits outweigh potential risks. Store at room temperature: keep in the original packaging, protect from moisture and light.
What does Dexketoprofen interact with?
Dexketoprofen may interact with several drug classes.
Major Interactions (Avoid): - Anticoagulants (e.g., warfarin): increased risk of bleeding. - Other NSAIDs or COX‑2 inhibitors: additive gastrointestinal toxicity. - Selective serotonin reuptake inhibitors (SSRIs): heightened bleeding tendency. - Corticosteroids: elevated ulcer risk.
Moderate Interactions (Monitor Closely): - ACE inhibitors or ARBs: possible reduction in renal function. - Diuretics: may affect renal clearance of Dexketoprofen.



