GNH USA

Europe — EMA

Ketoconazole Zydus

GNH USA supplies Ketoconazole Zydus (Ketoconazole), an azole antifungal for dermatophytosis and seborrheic dermatitis. Request a quote for supply.

Ketoconazole

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What is Ketoconazole?

Ketoconazole, the active ingredient in Ketoconazole Zydus, is an azole antifungal presented as a topical formulation for skin use. It treats fungal skin infections such as dermatophytosis, seborrheic dermatitis and pityriasis versicolor in adult and pediatric patients as directed by a healthcare professional.

GNH USA supplies Ketoconazole Zydus as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

What is Ketoconazole used for?

Ketoconazole is an azole antifungal that targets fungal skin infections.

Dermatophytosis: clears fungal infection and reduces itching, scaling and redness. Seborrheic dermatitis: diminishes scaling, erythema and oiliness. Pityriasis versicolor: eradicates Malassezia overgrowth and restores normal skin colour.

What are the side effects of Ketoconazole?

Topical ketoconazole may cause local skin reactions.

Common Side Effects: - Itching or mild burning sensation at the application site. - Redness or erythema. - Dryness or flaking of the skin. - Stinging or tingling. - Mild irritation or contact dermatitis. - Peeling of the treated area.

Serious or Rare Side Effects: - Severe allergic reaction (e.g., swelling, hives, difficulty breathing). - Extensive skin rash or Stevens‑Johnson syndrome. - Significant swelling or blistering of the skin. - Systemic absorption leading to liver enzyme abnormalities. - Photosensitivity causing exaggerated sunburn. - Persistent or worsening irritation requiring medical attention.

What precautions apply to Ketoconazole?

Before using Ketoconazole Zydus, consider the following safety measures.

Avoid application on broken skin: may increase irritation. Do not use with other topical antifungals without medical advice. Limit exposure to sunlight: risk of photosensitivity. Discontinue if severe irritation occurs: seek medical evaluation. Store at room temperature below 25°C: keep in the original container, protect from moisture and light.

What does Ketoconazole interact with?

Ketoconazole may interact with other topical or systemic agents.

Major Interactions (Avoid): - Concurrent use with systemic azole antifungals: may increase systemic absorption. - Application with topical products containing alcohol or strong irritants.

Moderate Interactions (Monitor Closely): - Co‑application with topical retinoids: monitor for increased irritation. - Use with sunscreen: may reduce antifungal efficacy. - Combination with other antifungal creams: assess for redundancy. - Concurrent use with corticosteroid creams: monitor for altered skin healing.

Frequently asked questions

What is Ketoconazole Zydus used for?+
Ketoconazole Zydus is a topical antifungal medication indicated for the treatment of dermatophytosis (such as tinea corporis, tinea cruris and tinea pedis), seborrheic dermatitis and pityriasis versicolor. It works by eliminating the fungi responsible for these skin conditions, helping to relieve symptoms like itching, scaling and redness.
How does ketoconazole work?+
Ketoconazole belongs to the azole class of antifungals. It blocks the fungal enzyme lanosterol 14α‑demethylase, which is essential for synthesising ergosterol, a key component of the fungal cell membrane. Without ergosterol, the membrane becomes defective, leading to fungal cell death and resolution of the infection.
What is the usual dose of Ketoconazole Zydus?+
The dosing regimen for Ketoconazole Zydus is determined by the prescribing healthcare professional. Typically, a thin layer of the cream or gel is applied to the affected area once or twice daily, following the instructions on the product label and the clinician’s guidance.
Is Ketoconazole Zydus safe in pregnancy or breastfeeding?+
Safety data for topical ketoconazole during pregnancy and lactation are limited. The product should only be used if the prescriber judges that the potential benefit outweighs any possible risk to the fetus or infant. Women who are pregnant, planning pregnancy, or breastfeeding should discuss alternatives with their doctor.
How do I order Ketoconazole Zydus from GNH USA?+
To place an order, submit an enquiry on the product page at gnh-usa.com, specifying the required quantity. GNH USA works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including any cold‑chain requirements) and the necessary import documentation.
How does Ketoconazole Zydus compare with other topical antifungals?+
Ketoconazole is a broad‑spectrum azole, effective against dermatophytes and yeasts, whereas agents like clotrimazole or miconazole have a similar spectrum but may differ in potency, formulation and dosing frequency. Ketoconazole often requires once‑ or twice‑daily application, and its anti‑inflammatory properties can be advantageous in seborrheic dermatitis.
What are the storage and handling requirements for Ketoconazole Zydus?+
Ketoconazole Zydus should be stored at room temperature, below 25 °C, in its original packaging. Keep the container tightly closed, protect it from moisture and direct sunlight, and ensure it is out of reach of children.
How is Ketoconazole Zydus administered?+
The product is applied topically. Clean and dry the affected skin area, then spread a thin, even layer of the cream or gel over the lesion. Wash hands before and after application, and avoid contact with eyes, mouth or open wounds unless directed by a healthcare professional.
What are the most serious risks associated with Ketoconazole Zydus?+
Although rare, serious adverse reactions can include severe allergic responses such as swelling, hives, or difficulty breathing, as well as extensive skin rashes like Stevens‑Johnson syndrome. Systemic absorption may lead to liver enzyme abnormalities, especially if used over large body surface areas. Prompt medical attention is required if any of these symptoms develop.
Who should not use Ketoconazole Zydus?+
Individuals with a known hypersensitivity to ketoconazole, other azole antifungals, or any component of the formulation should avoid using the product. It is also contraindicated on extensive broken or inflamed skin, and caution is advised in patients with pre‑existing liver disease or those taking systemic azole medications.
Information provided on this page is for educational use by procurement and clinical professionals. Always consult a licensed healthcare provider for medical advice and prescribing decisions. GNH USA supplies this product subject to applicable regulatory and licensing requirements.

Product details

Drug
Ketoconazole
Route
Cutaneous Use
Manufacturer
Zydus France
Origin
EU

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