Ketesse

Dexketoprofen, the active ingredient in Ketesse, is a Nonsteroidal anti-inflammatory drug (NSAID) presented as an injectable solution for intramuscular and intravenous use. It is employed to relieve acute pain, post‑operative discomfort, musculoskeletal pain and inflammation in adult patients.

GNH USA supplies Ketesse as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Dexketoprofen acts as an analgesic and anti‑inflammatory agent within the NSAID class, targeting conditions that involve pain and inflammation. - Acute pain: provides rapid relief of moderate to severe pain episodes. - Post‑operative pain: reduces pain intensity after surgical procedures. - Musculoskeletal pain: alleviates pain associated with strains, sprains and other musculoskeletal injuries. - Inflammation: diminishes inflammatory response in affected tissues.

Adverse reactions may occur with dexketoprofen administration. Most are mild and reversible, while a few can be serious and require immediate medical attention.

Common Side Effects: - Nausea: mild to moderate upset stomach. - Headache: transient cranial discomfort. - Dizziness: occasional light‑headedness. - Injection‑site pain: local discomfort at the administration site.

Serious or Rare Side Effects: - Gastrointestinal bleeding: signs of blood in stool or vomit. - Severe allergic reaction: rash, swelling, or difficulty breathing. - Renal impairment: reduced urine output or swelling. - Hepatic dysfunction: jaundice or elevated liver enzymes. - Cardiovascular events: chest pain or sudden shortness of breath.

Before using dexketoprofen, consider the following safety measures. - Assess renal function: avoid use in patients with severe renal impairment. - Evaluate hepatic status: monitor liver enzymes in those with liver disease. - Review gastrointestinal history: caution in patients with ulcers or bleeding disorders. - Avoid concurrent NSAIDs: increase risk of bleeding and ulceration. - Monitor cardiovascular risk: use cautiously in patients with hypertension or heart disease. - Store at ambient temperature: keep below 25 °C, protect from moisture and light in the original packaging.

Dexketoprofen may interact with other medicines, altering efficacy or safety.

Major Interactions (Avoid): - Anticoagulants (e.g., warfarin): heightened risk of serious bleeding. - High‑dose aspirin or other NSAIDs: additive gastrointestinal toxicity. - Selective serotonin reuptake inhibitors (SSRIs): increased bleeding tendency.

Moderate Interactions (Monitor Closely): - ACE inhibitors or diuretics: possible reduction in renal function. - Lithium: potential rise in lithium serum levels.