GNH USA

Europe — EMA

Ketesse

GNH USA supplies Ketesse (Dexketoprofen), a nonsteroidal anti-inflammatory drug for acute, postoperative and dental pain. Request a quote for global supply.

Dexketoprofen

Request sourcing

1
Pack/s

What is Dexketoprofen?

Dexketoprofen, the active ingredient in Ketesse, is a nonsteroidal anti-inflammatory drug (NSAID) presented as an injectable solution for intramuscular and intravenous use. It treats acute pain, postoperative pain, musculoskeletal pain and dental pain in adult patients, providing rapid analgesia after surgical or traumatic events.

GNH USA supplies Ketesse as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

What is Dexketoprofen used for?

Dexketoprofen is an NSAID that reduces inflammation and pain by inhibiting cyclooxygenase enzymes.

Acute pain: provides rapid relief of severe short‑term pain. Postoperative pain: helps control discomfort following surgical procedures. Musculoskeletal pain: alleviates pain associated with strains, sprains and arthritis. Dental pain: relieves pain after dental extractions or other oral procedures.

What are the side effects of Dexketoprofen?

Adverse reactions may occur with any NSAID therapy.

Common Side Effects: - Injection site pain - Nausea - Headache - Dizziness

Serious or Rare Side Effects: - Gastrointestinal ulcer or bleeding - Severe allergic reaction (anaphylaxis) - Renal function decline - Cardiovascular thrombotic events

What precautions apply to Dexketoprofen?

Careful assessment and monitoring are required when using Dexketoprofen injectable.

Assess renal function: evaluate baseline creatinine and adjust use in renal impairment. Evaluate hepatic function: monitor liver enzymes, especially in patients with liver disease. Use caution in cardiovascular disease: consider increased risk of thrombotic events. Avoid in known hypersensitivity to NSAIDs or dexketoprofen. Monitor for gastrointestinal ulcer risk: co‑prescribe gastro‑protective agents if needed. Store at 2-8°C: keep refrigerated, protect from light, do not freeze or shake.

What does Dexketoprofen interact with?

Dexketoprofen may interact with several drug classes.

Major Interactions (Avoid): - Warfarin: increased bleeding risk. - Other NSAIDs: additive gastrointestinal toxicity. - ACE inhibitors: potential reduction in renal perfusion.

Moderate Interactions (Monitor Closely): - Diuretics: heightened risk of renal impairment. - SSRIs: possible enhancement of bleeding tendency.

Frequently asked questions

What is Ketesse used for?+
Ketesse is an injectable formulation of dexketoprofen, an NSAID indicated for the short‑term management of acute pain, postoperative pain, musculoskeletal pain and dental pain in adult patients. It is administered by intramuscular or intravenous injection to provide rapid analgesia.
How does dexketoprofen work?+
Dexketoprofen works by reversibly inhibiting the cyclooxygenase‑1 and cyclooxygenase‑2 enzymes, which reduces the synthesis of prostaglandins. Lower prostaglandin levels lead to decreased inflammation, reduced peripheral sensitisation of pain receptors, and consequently provide analgesic and antipyretic effects.
What is the usual dose of Ketesse?+
The specific dose and frequency of Ketesse are determined by the prescribing clinician based on the severity of pain, the route of administration (intramuscular or intravenous), and the individual patient’s clinical condition. No fixed regimen is provided here.
Is Ketesse safe to use during pregnancy or breastfeeding?+
Safety data for dexketoprofen in pregnancy and lactation are limited, and the product does not have an established pregnancy category. It should only be used if the potential benefit justifies the potential risk to the fetus or infant, and under close medical supervision.
How do I order Ketesse from GNH USA?+
To request Ketesse, submit an enquiry on the product page at gnh-usa.com, specifying the required quantity. GNH USA works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including cold‑chain where required) and necessary import documentation.
How does Ketesse compare with other NSAIDs?+
Ketesse (dexketoprofen) is the S‑enantiomer of ketoprofen, offering a faster onset of analgesia and potentially lower gastrointestinal side‑effects compared with racemic ketoprofen. Compared with ibuprofen or diclofenac, dexketoprofen provides comparable pain relief at lower doses, but the safety profile remains similar to other NSAIDs.
What are the storage and handling requirements for Ketesse?+
Ketesse must be stored at 2‑8 °C in a refrigerator, protected from light, and must not be frozen or shaken. The vial should remain in its original packaging until use to maintain stability and sterility.
How is Ketesse administered?+
Ketesse is supplied as a sterile injectable solution for intramuscular or intravenous injection. Administration is performed by a qualified healthcare professional, following aseptic technique and the dosage instructions provided by the prescriber.
What are the most serious risks associated with Ketesse?+
Serious risks include gastrointestinal ulceration or bleeding, severe allergic reactions such as anaphylaxis, renal impairment, and cardiovascular events like myocardial infarction or stroke. Patients should be monitored closely for signs of these conditions, especially if they have pre‑existing risk factors.
Who should not use Ketesse?+
Ketesse should be avoided in patients with known hypersensitivity to dexketoprofen or other NSAIDs, those with active gastrointestinal bleeding or ulcer disease, severe renal or hepatic impairment, and individuals with uncontrolled cardiovascular disease unless specifically directed by a physician.
Information provided on this page is for educational use by procurement and clinical professionals. Always consult a licensed healthcare provider for medical advice and prescribing decisions. GNH USA supplies this product subject to applicable regulatory and licensing requirements.
Send a sourcing enquiry for this product →

Product details

Drug
Dexketoprofen
Route
Intramuscular Use , Intravenous Use
Manufacturer
Menarini International Operations Luxembourg S.A.
Origin
EU

Related products

A

A

Liquid Extract From Viscum Album Subsp. Abietis Var Abies Alba (1:20), Extraction Solvents: Water Fo

Helixor Heilmittel Gmbh
EU
A

A

Liquid Extract From Viscum Album Subsp. Abietis Var Abies Alba (1:20), Extraction Solvents: Water Fo

Helixor Heilmittel Gmbh
EU
A

A

Liquid Extract From Viscum Album Subsp. Abietis Var Abies Alba (1:20), Extraction Solvents: Water Fo

Helixor Heilmittel Gmbh
EU
A

A

Liquid Extract From Viscum Album Subsp. Abietis Var Abies Alba (1:20), Extraction Solvents: Water Fo

Helixor Heilmittel Gmbh
EU