GNH USA

Europe — EMA

Ketazed

GNH USA supplies Ketazed (Ketotifen Hydrogen Fumarate), an antihistamine for allergic conjunctivitis and seasonal allergic eye disease. Request a quote.

Ketotifen Hydrogen Fumarate

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What is Ketotifen Hydrogen Fumarate?

Ketotifen hydrogen fumarate, the active ingredient in Ketazed, is an antihistamine (mast cell stabilizer) presented as an ophthalmic preparation for ocular use. It is employed to manage allergic conjunctivitis and related seasonal allergic eye conditions in patients requiring topical therapy.

GNH USA supplies Ketazed as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

What is Ketotifen Hydrogen Fumarate used for?

Ketazed acts on ocular allergic pathways to relieve inflammation and itching associated with allergic eye disease. - Allergic conjunctivitis: reduces ocular itching, redness, and tearing. - Seasonal allergic eye disease: stabilises mast cells to prevent episodic symptoms during pollen seasons. - Vernal keratoconjunctivitis: helps control chronic inflammation and photophobia in severe seasonal forms.

What are the side effects of Ketotifen Hydrogen Fumarate?

Ketazed may cause ocular and systemic reactions in some patients.

Common Side Effects: - Burning or stinging sensation upon instillation. - Transient blurred vision. - Mild eye irritation or redness. - Dry eye sensation. - Headache. - Temporary increased tearing.

Serious or Rare Side Effects: - Severe allergic reaction (anaphylaxis) with swelling of eyelids or face. - Corneal ulcer or keratitis. - Persistent intra‑ocular inflammation. - Vision loss. - Severe eye pain. - Acute hypersensitivity dermatitis around the eye.

What precautions apply to Ketotifen Hydrogen Fumarate?

Before using Ketazed, consider the following safety measures. - Pregnancy: consult a healthcare professional before use. - Breastfeeding: discuss potential risks with a physician. - Contact lens wearers: avoid use unless advised by an eye specialist. - Existing ocular infection: evaluate and treat infection prior to administration. - Concomitant ocular medications: assess for possible interactions. - Store at below 25°C: keep in the original container, protect from light and moisture.

What does Ketotifen Hydrogen Fumarate interact with?

Ketazed may interact with other ocular or systemic agents.

Major Interactions (Avoid): - No major drug interactions have been identified for ocular use of ketotifen.

Moderate Interactions (Monitor Closely): - Systemic antihistamines: may increase ocular dryness. - Topical corticosteroids: could mask signs of infection. - Other mast cell stabilizers: additive effect may increase local irritation. - Beta‑blocker eye drops: monitor intra‑ocular pressure if used together. - Preservative‑containing drops: may enhance irritation when combined.

Frequently asked questions

What is Ketazed used for?+
Ketazed is an ophthalmic preparation containing ketotifen hydrogen fumarate. It is used to treat allergic conjunctivitis and seasonal allergic eye disease by reducing itching, redness, and swelling of the eyes caused by allergic reactions.
How does ketotifen hydrogen fumarate work in the eye?+
Ketotifen hydrogen fumarate blocks histamine H1 receptors on ocular tissues and stabilises mast cells, preventing the release of inflammatory mediators such as histamine, leukotrienes, and prostaglandins. This dual action limits the allergic response and alleviates eye symptoms.
What is the usual dose of Ketazed?+
The dosing regimen for Ketazed is determined by the prescribing eye‑care professional. Typically, the recommended frequency and number of drops per eye are specified on the prescription based on the severity of the allergic condition.
Is Ketazed safe during pregnancy or breastfeeding?+
Safety data for ketotifen hydrogen fumarate in pregnancy and lactation are limited. Women who are pregnant, planning to become pregnant, or breastfeeding should discuss potential risks and benefits with their healthcare provider before using Ketazed.
How do I order Ketazed from GNH USA?+
To request Ketazed, submit an enquiry on the product page at gnh-usa.com, indicating the required quantity. GNH USA works with hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details, and any necessary import documentation.
How does Ketazed compare with other allergic eye treatments?+
Ketazed belongs to the antihistamine‑mast cell stabiliser class, offering both immediate histamine blockade and longer‑term mast‑cell stabilization. Compared with pure antihistamine drops, it may provide more sustained symptom control, while it differs from corticosteroid eye drops that are reserved for more severe inflammation due to higher side‑effect potential.
What are the storage requirements for Ketazed?+
Ketazed should be stored at temperatures below 25 °C, in its original container, protected from light and moisture. Do not freeze the product, and keep it out of reach of children.
How is Ketazed administered?+
Ketazed is applied as eye drops. The patient should wash hands, tilt the head back, pull down the lower eyelid, and place the prescribed number of drops into the conjunctival sac. The eye should be closed gently for a few seconds to allow absorption.
What are the most serious risks associated with Ketazed?+
Serious risks, although rare, include severe allergic reactions such as anaphylaxis, corneal ulceration, and persistent intra‑ocular inflammation. Any sudden worsening of vision, intense eye pain, or swelling should prompt immediate medical attention.
Who should not use Ketazed?+
Ketazed should be avoided in individuals with known hypersensitivity to ketotifen or any component of the formulation. Patients with active ocular infections or severe ocular surface disease should consult an eye specialist before use.
Information provided on this page is for educational use by procurement and clinical professionals. Always consult a licensed healthcare provider for medical advice and prescribing decisions. GNH USA supplies this product subject to applicable regulatory and licensing requirements.

Product details

Drug
Ketotifen Hydrogen Fumarate
Route
Ocular Use
Manufacturer
Horus Pharma
Origin
EU

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