GNH USA

Europe — EMA

Ketazed

GNH USA supplies Ketazed (Ketotifen Hydrogen Fumarate), an antihistamine/mast cell stabilizer for allergic conjunctivitis and ocular itching.

Ketotifen Hydrogen Fumarate

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What is Ketotifen Hydrogen Fumarate?

Ketotifen hydrogen fumarate, the active ingredient in Ketazed, is an antihistamine / mast cell stabilizer presented as an ocular solution for ocular use. It treats allergic conjunctivitis and ocular itching or redness caused by allergy in both adults and children.

GNH USA supplies Ketazed as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

What is Ketotifen Hydrogen Fumarate used for?

Ketazed is used to manage ocular allergic conditions by stabilising mast cells and blocking histamine effects.

Allergic conjunctivitis: reduces inflammation and discomfort in the eyes caused by allergens. Ocular itching due to allergy: relieves itching sensations associated with allergic reactions. Redness from allergic eye disease: diminishes visible redness and swelling in the conjunctiva.

What are the side effects of Ketotifen Hydrogen Fumarate?

Ketazed may cause ocular or systemic reactions, although many patients experience no adverse events.

Common Side Effects: - Burning or stinging sensation upon instillation. - Temporary blurred vision. - Mild eye irritation or foreign‑body feeling. - Slight headache. - Dryness of the ocular surface.

Serious or Rare Side Effects: - Severe allergic reaction (anaphylaxis) with swelling of the eyelids or face. - Persistent eye pain or significant vision changes. - Corneal ulceration or infection. - Acute angle‑closure glaucoma. - Significant systemic hypersensitivity (rash, urticaria).

What precautions apply to Ketotifen Hydrogen Fumarate?

Before using Ketazed, consider the following safety measures.

Avoid use in patients with known hypersensitivity to ketotifen or any formulation component: discontinue if reaction occurs. Do not apply if the eye is infected or has a corneal ulcer: seek professional evaluation first. Use with caution in patients with narrow-angle glaucoma: monitor intra‑ocular pressure. Pregnancy and breastfeeding status unknown: consult a healthcare professional before use. Store at room temperature: keep in the original container, protect from light and moisture.

What does Ketotifen Hydrogen Fumarate interact with?

Ketazed may interact with other ocular or systemic agents.

Major Interactions (Avoid): - Concurrent use of other mast cell stabilizers (e.g., cromolyn) may increase local irritation. - Co‑administration with potent topical corticosteroids may mask signs of infection.

Moderate Interactions (Monitor Closely): - Systemic antihistamines (e.g., cetirizine) could enhance sedation if systemic absorption occurs. - Contact lens wearers: may experience reduced lens tolerance; advise removal before instillation. - Use with other ophthalmic solutions containing preservatives: monitor for additive irritation.

Frequently asked questions

What is Ketazed used for?+
Ketazed is an ophthalmic solution containing ketotifen hydrogen fumarate. It is used to relieve symptoms of ocular allergy such as itching, redness, and swelling caused by allergic conjunctivitis. The medication works locally in the eye to reduce inflammation and improve comfort.
How does ketotifen hydrogen fumarate work?+
Ketotifen hydrogen fumarate stabilises mast cells, preventing them from releasing histamine and other inflammatory mediators. It also blocks histamine H1 receptors on ocular tissues. By limiting both the release and the action of histamine, the drug reduces the allergic response in the eye.
What is the usual dose of Ketazed?+
The dosing regimen for Ketazed is determined by the prescribing clinician based on the severity of the allergic eye condition and the patient’s age. Typically, one or two drops are instilled in the affected eye(s) as directed, but the exact schedule should follow the healthcare professional’s instructions.
Is Ketazed safe during pregnancy or breastfeeding?+
Safety data for ketotifen hydrogen fumarate in pregnancy and lactation are limited. Women who are pregnant, planning to become pregnant, or breastfeeding should discuss potential risks and benefits with their healthcare provider before using Ketazed.
How do I order Ketazed from GNH USA?+
To order Ketazed, submit an enquiry on the product page at gnh-usa.com specifying the required quantity. GNH USA works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.
How does Ketazed compare with other ocular antihistamines?+
Ketazed combines mast‑cell stabilisation with H1‑receptor blockade, offering both preventive and symptomatic relief. Some alternatives provide only antihistamine activity, which may relieve itching but not prevent mediator release. The dual mechanism of ketotifen can give broader control of allergic eye symptoms.
How should Ketazed be stored and handled?+
Ketazed should be stored at room temperature, below 25 °C, in its original container. Keep the bottle tightly closed, protect it from direct sunlight and moisture, and avoid freezing. Do not use the product if the solution appears discoloured or if the container is damaged.
How is Ketazed administered?+
Ketazed is applied as an eye drop. The patient should wash hands, tilt the head back, pull down the lower eyelid to create a small pocket, and place the prescribed number of drops into the conjunctival sac. Close the eye gently and avoid blinking excessively for a few seconds.
What are the most serious risks associated with Ketazed?+
Serious risks, though rare, include severe allergic reactions such as anaphylaxis, significant eye pain, sudden vision loss, corneal ulceration, or acute angle‑closure glaucoma. Any of these symptoms require immediate medical attention and discontinuation of the product.
Who should not use Ketazed?+
Ketazed should not be used by individuals with a known hypersensitivity to ketotifen hydrogen fumarate or any excipients in the formulation. It is also contraindicated in eyes with active infection, corneal ulceration, or in patients with narrow‑angle glaucoma unless specifically advised by an eye‑care professional.
Information provided on this page is for educational use by procurement and clinical professionals. Always consult a licensed healthcare provider for medical advice and prescribing decisions. GNH USA supplies this product subject to applicable regulatory and licensing requirements.

Product details

Drug
Ketotifen Hydrogen Fumarate
Route
Ocular Use
Manufacturer
Horus Pharma
Origin
EU

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