GNH USA

Europe — EMA

Ketazed

GNH USA supplies Ketazed (Ketotifen Hydrogen Fumarate), a H1 antihistamine ophthalmic agent for allergic conjunctivitis and ocular itching.

Ketotifen Hydrogen Fumarate

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What is Ketotifen Hydrogen Fumarate?

Ketotifen hydrogen fumarate, the active ingredient in Ketazed, is a H1 receptor antagonist presented as an ophthalmic preparation for ocular use. It is employed to relieve symptoms of allergic conjunctivitis, ocular itching and redness caused by allergic eye disease.

GNH USA supplies Ketazed as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

What is Ketotifen Hydrogen Fumarate used for?

Ketazed is an ophthalmic antihistamine used to manage allergic eye conditions. It works by stabilising mast cells and blocking H1 receptors in the conjunctiva.

Allergic conjunctivitis: reduces eye redness, swelling and itching caused by allergens. Ocular itching: provides rapid relief from itch sensations in the eye. Redness due to allergic eye disease: diminishes hyperemia and discomfort associated with allergic inflammation.

What are the side effects of Ketotifen Hydrogen Fumarate?

Ketazed may cause local ocular reactions, most of which are mild and transient.

Common Side Effects: - Burning or stinging sensation upon instillation. - Temporary blurred vision. - Mild eye irritation or foreign‑body feeling. - Conjunctival hyperemia (redness).

Serious or Rare Side Effects: - Allergic reaction with swelling of the eyelids or periorbital area. - Severe eye pain or photophobia. - Corneal ulceration or keratitis. - Sudden loss of vision. - Persistent inflammation requiring medical attention.

What precautions apply to Ketotifen Hydrogen Fumarate?

When using Ketazed, consider the following safety measures.

Avoid use with contact lenses: remove lenses before and after application. Discontinue if severe irritation occurs: seek ophthalmic evaluation. Limit duration of use: consult a clinician if symptoms persist beyond one week. Keep out of reach of children: accidental ingestion may cause systemic effects. Store at room temperature below 25°C: keep in the original container, protect from moisture and direct sunlight.

What does Ketotifen Hydrogen Fumarate interact with?

Ketazed may interact with other ophthalmic or systemic agents.

Major Interactions (Avoid): - Concurrent use of other topical antihistamine eye drops: may increase local irritation. - Combination with ocular vasoconstrictors (e.g., naphazoline): risk of excessive vasoconstriction.

Moderate Interactions (Monitor Closely): - Systemic antihistamines (e.g., cetirizine): additive sedative effect is unlikely but monitor for increased dryness. - Topical non‑steroidal anti‑inflammatory eye drops: may enhance ocular discomfort. - Preservative‑containing eye solutions: monitor for cumulative preservative toxicity.

Frequently asked questions

What conditions is Ketazed used to treat?+
Ketazed is indicated for the relief of ocular allergy symptoms such as allergic conjunctivitis, eye itching and redness caused by allergic eye disease. It works locally in the eye to reduce inflammation and discomfort associated with these conditions.
How does ketotifen hydrogen fumarate work in the eye?+
Ketotifen hydrogen fumarate stabilises mast cells, preventing the release of histamine and other inflammatory mediators. It also blocks H1 histamine receptors on conjunctival vessels and nerves, reducing vasodilation, itching and swelling that occur during allergic reactions.
What is the usual dose of Ketazed?+
The dosing regimen for Ketazed is determined by the prescribing eye‑care professional. Typically, one or two drops are instilled in the affected eye(s) as directed, but the exact frequency and duration should follow the prescriber’s instructions.
Is Ketazed safe to use during pregnancy or breastfeeding?+
Safety data for ketotifen hydrogen fumarate in pregnancy and lactation are limited. Women who are pregnant, planning to become pregnant, or breastfeeding should discuss potential risks and benefits with their healthcare provider before using Ketazed.
How do I order Ketazed from GNH USA?+
To place an order, submit an enquiry on the product page at gnh-usa.com, specifying the required quantity. GNH USA works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.
How does Ketazed compare with other eye allergy treatments?+
Ketazed combines mast‑cell stabilisation with H1‑receptor antagonism, offering both preventive and symptomatic relief. Compared with agents that provide only antihistamine activity, Ketazed may give longer‑lasting control of ocular allergy symptoms, though individual response can vary.
What are the recommended storage conditions for Ketazed?+
Ketazed should be stored at room temperature below 25 °C. Keep the bottle tightly closed, protect it from moisture and direct sunlight, and retain it in the original packaging until use.
How is Ketazed administered?+
Ketazed is applied topically to the eye as an ophthalmic solution. The prescribed number of drops is placed into the conjunctival sac of the affected eye(s) without touching the tip of the bottle to the eye or surrounding tissues.
What are the most serious risks associated with Ketazed?+
Serious adverse reactions, although rare, include severe allergic responses such as eyelid swelling, corneal ulceration, and sudden loss of vision. If any of these occur, discontinue use immediately and seek urgent ophthalmic care.
Who should not use Ketazed?+
Ketazed should be avoided by individuals with known hypersensitivity to ketotifen or any component of the formulation. Patients with active ocular infections or severe ocular surface disease should consult an eye‑care professional before use.
Information provided on this page is for educational use by procurement and clinical professionals. Always consult a licensed healthcare provider for medical advice and prescribing decisions. GNH USA supplies this product subject to applicable regulatory and licensing requirements.

Product details

Drug
Ketotifen Hydrogen Fumarate
Route
Ocular Use
Manufacturer
Horus Pharma
Origin
EU

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