GNH USA

Europe — EMA

Ketazed

GNH USA supplies Ketazed (Ketotifen hydrogen fumarate), an ocular antihistamine for allergic conjunctivitis and eye itching. Request a quote for supply.

Ketotifen Hydrogen Fumarate

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What is Ketotifen Hydrogen Fumarate?

Ketotifen hydrogen fumarate, the active ingredient in Ketazed, is an antihistamine (H1 receptor antagonist) presented as an ocular solution for eye‑drop use. It is indicated for the relief of allergic conjunctivitis and associated ocular itching, redness, and watery discharge in patients with seasonal or perennial eye allergies.

GNH USA supplies Ketazed as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide, providing reliable access to this EU‑approved OTC ocular antihistamine for eye‑care professionals and patients, with consistent quality and regulatory compliance.

What is Ketotifen Hydrogen Fumarate used for?

Ketazed is used to manage allergic eye conditions by blocking histamine activity in the conjunctiva.

Allergic conjunctivitis: reduces itching, redness, and tearing associated with seasonal or perennial eye allergies. Seasonal allergic eye disease: provides symptom relief during pollen or allergen exposure. Contact lens‑related ocular itching: alleviates discomfort caused by allergic reactions in contact lens wearers.

What are the side effects of Ketotifen Hydrogen Fumarate?

Ketazed may cause ocular and systemic adverse reactions, most of which are mild and transient.

Common Side Effects: - Eye irritation or burning sensation - Transient blurred vision - Mild headache

Serious or Rare Side Effects: - Severe allergic reaction (anaphylaxis) with swelling of eyelids or face - Corneal ulcer or keratitis - Significant increase in intra‑ocular pressure

What precautions apply to Ketotifen Hydrogen Fumarate?

Before using Ketazed, consider the following safety measures.

Hypersensitivity: discontinue use if signs of allergic reaction appear. Contact lens use: avoid wearing contact lenses during treatment and for at least 15 minutes after instillation. Dosage: use only the prescribed number of drops as directed by a healthcare professional. Monitoring: seek medical advice if symptoms worsen or persist beyond a few days. Driving or operating machinery: exercise caution if blurred vision occurs. Store at room temperature: keep in original container, protect from moisture and light.

What does Ketotifen Hydrogen Fumarate interact with?

Ketazed can interact with other medicines; review the following categories.

Major Interactions (Avoid): - Systemic antihistamines: concurrent use may increase sedation and ocular dryness. - CYP450 inhibitors (e.g., ketoconazole): may raise systemic exposure of ketotifen. - Other mast‑cell stabilizers: combined use may increase risk of ocular irritation.

Moderate Interactions (Monitor Closely): - Topical corticosteroids: may augment intra‑ocular pressure when used together. - Contact lens cleaning solutions: can affect drug stability; avoid mixing. - Other ocular decongestants: may cause additive vasoconstriction.

Frequently asked questions

What is Ketazed used for?+
Ketazed is an ocular antihistamine indicated for the treatment of allergic conjunctivitis and related eye symptoms such as itching, redness, and tearing. It is used in patients who experience seasonal or perennial eye allergies and provides relief by targeting the underlying histamine response in the eye.
How does ketotifen hydrogen fumarate work?+
Ketotifen hydrogen fumarate works by stabilizing mast cells and blocking H1 histamine receptors on ocular tissues. This dual action prevents the release of histamine and other inflammatory mediators, reducing vascular permeability and nerve irritation in the conjunctiva, which alleviates itching, redness, and swelling.
What is the usual dose of Ketazed?+
The specific dosing regimen for Ketazed is determined by the prescribing healthcare professional based on the patient’s age, severity of symptoms, and response to therapy. Patients should follow the exact instructions provided on the prescription label and consult their clinician for any dosing questions.
Is Ketazed safe to use during pregnancy or breastfeeding?+
Safety data for ketotifen hydrogen fumarate in pregnancy and lactation are limited. Women who are pregnant, planning to become pregnant, or breastfeeding should discuss potential risks and benefits with their healthcare provider before using Ketazed, as the prescriber will decide whether it is appropriate.
How do I order Ketazed from GNH USA?+
To order Ketazed, submit an enquiry on the product page at gnh-usa.com, specifying the required quantity. GNH USA supplies hospitals, pharmacies and procurement teams worldwide, and will request trade or institutional credentials. The sales team then replies with pricing, availability, shipping details and any required import documentation.
How does Ketazed compare with other ocular antihistamines?+
Ketazed (ketotifen hydrogen fumarate) offers both mast‑cell stabilization and H1‑receptor antagonism, providing a broader mechanism of action than many single‑target antihistamines. This can result in faster and more sustained symptom relief for allergic conjunctivitis, though individual response may vary and clinicians choose therapy based on patient needs.
What are the storage and handling requirements for Ketazed?+
Ketazed should be stored at room temperature, below 25 °C, in its original container. Keep the bottle tightly closed, protect it from moisture and direct sunlight, and avoid freezing. Do not use the product if the solution appears discoloured or if the container is damaged.
How is Ketazed administered?+
Ketazed is administered as eye drops. The patient should wash hands, tilt the head back, pull down the lower eyelid to create a small pocket, and instill the prescribed number of drops into the conjunctival sac. After dosing, close the eyes gently and avoid blinking excessively for a few seconds.
What are the most serious risks associated with Ketazed?+
Serious risks, though rare, include severe allergic reactions such as anaphylaxis, corneal ulcer or keratitis, and a significant increase in intra‑ocular pressure that could threaten vision. Patients should seek immediate medical attention if they experience swelling of the eyelids, intense eye pain, vision changes, or signs of systemic allergy.
Who should not use Ketazed?+
Ketazed should not be used by individuals with known hypersensitivity to ketotifen, its salts, or any excipients in the formulation. Patients with active ocular infections, severe ocular surface disease, or uncontrolled glaucoma should consult their eye‑care professional before using this product.
Information provided on this page is for educational use by procurement and clinical professionals. Always consult a licensed healthcare provider for medical advice and prescribing decisions. GNH USA supplies this product subject to applicable regulatory and licensing requirements.

Product details

Drug
Ketotifen Hydrogen Fumarate
Route
Ocular Use
Manufacturer
Horus Pharma
Origin
EU

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