GNH USA

Europe — EMA

Ketazed

GNH USA supplies Ketazed (Ketotifen Hydrogen Fumarate), an antihistamine for allergic conjunctivitis and ocular itching. Request a quote for global supply.

Ketotifen Hydrogen Fumarate

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What is Ketotifen Hydrogen Fumarate?

Ketotifen Hydrogen Fumarate, the active ingredient in Ketazed, is an antihistamine presented as an ophthalmic solution for ocular use. It is employed to relieve symptoms of allergic conjunctivitis, ocular itching and redness caused by allergic eye disease.

GNH USA supplies Ketazed as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

What is Ketotifen Hydrogen Fumarate used for?

Ketazed is an antihistamine eye drop that targets allergic inflammation of the ocular surface.

Allergic conjunctivitis: reduces redness, swelling and itching caused by seasonal or perennial allergens. Ocular itching: provides rapid relief of itchiness associated with eye allergies. Redness due to allergic eye disease: diminishes hyperemia and discomfort in affected eyes.

What are the side effects of Ketotifen Hydrogen Fumarate?

Ketazed may cause ocular and systemic reactions, most of which are mild and transient.

Common Side Effects: - Burning or stinging sensation upon instillation. - Temporary blurred vision. - Mild eye irritation or foreign‑body sensation. - Slight increase in tear production. - Mild conjunctival hyperemia.

Serious or Rare Side Effects: - Severe allergic reaction (e.g., angio‑edema of the eyelid). - Persistent eye pain or swelling. - Vision loss or sudden decrease in visual acuity. - Corneal ulceration or keratitis. - Persistent intra‑ocular pressure elevation.

What precautions apply to Ketotifen Hydrogen Fumarate?

Before using Ketazed, consider the following safety measures.

Hypersensitivity: discontinue if known allergy to ketotifen or any excipient. Contact lens wearers: remove lenses before instillation and wait several minutes before reinserting. Concurrent ocular steroids: monitor for masked infections. Pregnancy and lactation: consult a healthcare professional before use. Children: keep out of reach and use only as directed. Store at room temperature: keep in original container, protect from light and moisture.

What does Ketotifen Hydrogen Fumarate interact with?

Ketazed may interact with other ocular or systemic agents.

Major Interactions (Avoid): - Concurrent use with other mast‑cell stabilizers may increase ocular irritation. - Combination with preservative‑containing contact lens solutions can exacerbate burning. - Simultaneous administration of ocular corticosteroids may mask signs of infection.

Moderate Interactions (Monitor Closely): - Systemic antihistamines may enhance overall antihistaminic effect, leading to mild sedation. - Use with vasoconstrictor eye drops may increase risk of ocular hypertension. - Co‑administration with other OTC eye decongestants should be monitored for additive irritation.

Frequently asked questions

What conditions is Ketazed used to treat?+
Ketazed is indicated for the relief of ocular symptoms associated with allergic eye disease, including allergic conjunctivitis, eye itching and redness. It works locally in the eye to reduce inflammation and discomfort caused by allergens.
How does ketotifen hydrogen fumarate work in the eye?+
Ketotifen hydrogen fumarate stabilizes mast cells, preventing the release of histamine and other inflammatory mediators. It also blocks histamine H1 receptors on ocular tissues, which reduces vasodilation, vascular permeability and nerve activation that cause itching and redness.
What is the usual dose of Ketazed?+
The dosing regimen for Ketazed is determined by the prescribing eye‑care professional. Typically, one or two drops are instilled in the affected eye(s) as directed, but the exact frequency and duration should follow the prescriber’s instructions.
Is Ketazed safe to use during pregnancy or breastfeeding?+
Safety data for ketotifen hydrogen fumarate in pregnancy and lactation are limited. Women who are pregnant, planning to become pregnant, or breastfeeding should discuss potential risks and benefits with their healthcare provider before using Ketazed.
How do I order Ketazed from GNH USA?+
To request Ketazed, submit an enquiry on the product page at gnh-usa.com, specifying the required quantity. GNH USA supplies hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.
How does Ketazed compare with other ocular antihistamines?+
Ketazed contains ketotifen, which offers both antihistamine and mast‑cell stabilising actions, whereas many other ocular antihistamines provide only H1‑receptor blockade. This dual mechanism can give broader control of allergic eye symptoms, but individual response may vary.
What are the recommended storage conditions for Ketazed?+
Ketazed should be stored at room temperature, below 25 °C, in its original packaging. Keep the container tightly closed, protect it from light and moisture, and discard any product that appears discoloured or contaminated.
How is Ketazed administered?+
Ketazed is applied as an ophthalmic solution. The patient should wash hands, tilt the head back, pull down the lower eyelid, and place the prescribed number of drops into the conjunctival sac. Close the eye gently and avoid blinking excessively for a few seconds.
What are the most serious risks associated with Ketazed?+
Serious risks, though rare, include severe allergic reactions such as angio‑edema of the eyelid, persistent eye pain, sudden loss of vision, corneal ulceration and significant intra‑ocular pressure elevation. Any of these symptoms require immediate medical attention.
Who should not use Ketazed?+
Ketazed should not be used by individuals with a known hypersensitivity to ketotifen hydrogen fumarate or any component of the formulation. It is also contraindicated in patients with active ocular infections that require specific antimicrobial therapy until the infection is resolved.
Information provided on this page is for educational use by procurement and clinical professionals. Always consult a licensed healthcare provider for medical advice and prescribing decisions. GNH USA supplies this product subject to applicable regulatory and licensing requirements.

Product details

Drug
Ketotifen Hydrogen Fumarate
Route
Ocular Use
Manufacturer
Horus Pharma
Origin
EU

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