Ketanov

Ketorolac Trometamol, the active ingredient in Ketanov, is a nonsteroidal anti-inflammatory drug presented as a oral formulation for oral use. It is employed for short‑term management of moderate to severe pain, especially postoperative pain, in adult patients.

GNH USA supplies Ketanov as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Ketanov, a nonsteroidal anti‑inflammatory analgesic, is indicated for conditions that require rapid pain control.

- Postoperative pain: provides effective relief after surgical procedures. - Acute moderate‑to‑severe pain: reduces pain intensity in short‑term settings. - Short‑term pain management: used for brief periods when stronger analgesia is needed.

Adverse reactions may range from mild to severe and should be monitored during therapy.

Common Side Effects: - Dyspepsia: stomach discomfort or indigestion. - Nausea: feeling of sickness. - Headache: mild to moderate head pain. - Dizziness: transient light‑headedness. - Diarrhoea: loose stools. - Elevated blood pressure: modest rise in systolic/diastolic values.

Serious or Rare Side Effects: - Gastrointestinal ulceration or bleeding. - Renal impairment: reduced kidney function. - Severe hypersensitivity reactions: rash, angioedema, anaphylaxis. - Hepatotoxicity: abnormal liver enzymes. - Cardiovascular events: myocardial infarction or stroke. - Hematologic abnormalities: thrombocytopenia or bleeding disorders.

Before prescribing Ketanov, clinicians should evaluate patient‑specific risk factors and monitor for potential complications.

- Renal function: assess baseline creatinine and avoid in severe renal impairment. - Gastrointestinal risk: avoid in patients with active ulcer disease or history of GI bleeding. - Cardiovascular disease: use cautiously in patients with coronary artery disease or uncontrolled hypertension. - Concomitant NSAIDs or anticoagulants: increase bleeding risk; monitor closely. - Pregnancy and lactation: avoid unless benefits outweigh risks; data are limited. - Store at ambient temperature: keep below 25 °C, retain in original packaging, protect from moisture and direct sunlight.

Ketorolac can interact with several drug classes, altering efficacy or safety.

Major Interactions (Avoid): - Anticoagulants (e.g., warfarin): heightened risk of serious bleeding. - Other NSAIDs or COX‑2 inhibitors: additive gastrointestinal toxicity. - Selective serotonin reuptake inhibitors (SSRIs): increased bleeding tendency.

Moderate Interactions (Monitor Closely): - ACE inhibitors or ARBs: may reduce renal perfusion, especially in dehydrated patients. - Diuretics: potential for reduced renal function. - Lithium: NSAIDs can raise lithium levels, risking toxicity. - Methotrexate: decreased clearance may lead to toxicity.