Ketanov

Ketorolac trometamol, the active ingredient in Ketanov, is a nonsteroidal anti-inflammatory drug (NSAID) presented as an injectable solution for intramuscular and intravenous use. It is employed for short‑term management of moderate to severe pain in adult patients, typically after surgery, dental procedures, or in acute musculoskeletal or renal colic settings.

GNH USA supplies Ketanov as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, clinics and procurement teams worldwide, ensuring quality and regulatory compliance across all markets. The company adheres to stringent quality standards and provides reliable logistics for global distribution.

Ketanov (ketorolac trometamol) is used in the management of acute pain conditions where rapid analgesia is required. - Postoperative pain: provides effective short‑term relief after surgical procedures. - Renal colic: reduces pain associated with kidney stone passage. - Acute musculoskeletal pain: alleviates severe pain from sprains, strains or trauma. - Dental pain: controls moderate to severe pain following dental surgery. - Traumatic injury pain: offers rapid analgesia for severe injury‑related pain.

Like other NSAIDs, ketorolac can cause a range of adverse reactions, varying from mild to severe. Common Side Effects: - Nausea - Vomiting - Headache - Injection site pain Serious or Rare Side Effects: - Gastrointestinal bleeding or ulceration - Acute renal failure - Severe allergic reactions (anaphylaxis, Stevens‑Johnson syndrome)

When prescribing Ketanov, clinicians should consider several safety measures. - Assess renal function: evaluate creatinine clearance before initiating therapy. - Limit duration: use only for short‑term pain (typically ≤5 days) to reduce risk. - Avoid in patients with active peptic ulcer disease or gastrointestinal bleeding. - Monitor for bleeding: watch for signs of hemorrhage, especially when combined with anticoagulants. - Contraindicated in known hypersensitivity to ketorolac or other NSAIDs. - Store at room temperature: keep in original container, protect from moisture and light.

Ketorolac may interact with other medicines, requiring careful assessment. Major Interactions (Avoid): - Anticoagulants (e.g., warfarin, heparin): increased risk of bleeding. - Other NSAIDs or aspirin: additive gastrointestinal toxicity. - Lithium: ketorolac may raise lithium serum levels, risking toxicity. Moderate Interactions (Monitor Closely): - ACE inhibitors or ARBs: may reduce renal perfusion, monitor kidney function. - Diuretics: combined use can impair renal function, especially in dehydrated patients. - Methotrexate: reduced clearance may increase toxicity, monitor levels.