Ketanov

Ketorolac Trometamol, the active ingredient in Ketanov, is a nonsteroidal anti-inflammatory drug (NSAID) presented as an injectable solution for intramuscular use. It provides short‑term management of moderate to severe pain, including post‑operative pain, in adult patients.

GNH USA supplies Ketanov as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide, including surgical centres and emergency departments.

Ketorolac Trometamol is an NSAID used for acute pain management in the postoperative and trauma settings.

- Post‑operative pain: provides rapid analgesia for up to 24‑48 hours after surgery. - Acute severe pain: reduces pain intensity following injury, dental procedures or other short‑term painful events. - Musculoskeletal injury: helps control pain and inflammation after strains or sprains.

Adverse reactions may occur with any dose of ketorolac.

Common Side Effects: - Injection‑site pain or irritation. - Nausea or vomiting. - Headache. - Dizziness. - Mild gastrointestinal discomfort.

Serious or Rare Side Effects: - Renal impairment or failure. - Severe allergic reactions such as anaphylaxis. - Gastrointestinal ulceration or bleeding. - Cardiovascular thrombotic events (e.g., myocardial infarction, stroke). - Stevens‑Johnson syndrome or toxic epidermal necrolysis.

Before using Ketanov, clinicians should consider several safety measures.

- Assess renal function: avoid in patients with severe renal impairment. - Monitor for bleeding: use cautiously with anticoagulants or antiplatelet agents. - Avoid in patients with known hypersensitivity to NSAIDs or aspirin. - Limit duration: restrict treatment to five days or less to minimise adverse events. - Pregnancy and lactation: use only if the potential benefit justifies the potential risk. - Store at ambient temperature: keep in the original container, protect from light and moisture.

Ketorolac can interact with other medicines, requiring attention to avoid harmful effects.

Major Interactions (Avoid): - Anticoagulants (e.g., warfarin): increased risk of serious bleeding. - Other NSAIDs or COX‑2 inhibitors: additive gastrointestinal toxicity. - Selective serotonin reuptake inhibitors (SSRIs): heightened bleeding tendency.

Moderate Interactions (Monitor Closely): - ACE inhibitors: may reduce renal function when combined. - Diuretics: can impair renal clearance of ketorolac. - Lithium: may increase serum lithium concentrations, requiring monitoring.