GNH USA

Europe — EMA

Ketalar

GNH USA supplies Ketalar (ketamine), a dissociative anesthetic for induction of anesthesia, procedural sedation and acute pain. Request a quote for supply.

Ketamine

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What is Ketamine?

Ketamine, the active ingredient in Ketalar, is a dissociative anesthetic presented as an injectable solution for intramuscular and intravenous use. It is employed for induction and maintenance of anesthesia, procedural sedation, analgesia for acute pain, and as an off‑label adjunct in treatment‑resistant depression. GNH USA supplies Ketalar as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

What is Ketamine used for?

Ketalar (ketamine) is used in clinical settings for conditions requiring dissociative anesthesia or analgesia.

Induction and maintenance of general anesthesia: provides rapid, controllable unconsciousness for surgical procedures. Procedural sedation: enables safe sedation for diagnostic or minor therapeutic procedures. Acute pain management: delivers analgesia for severe pain when other agents are insufficient. Adjunct in treatment‑resistant depression (off‑label): offers rapid antidepressant effects in selected patients.

What are the side effects of Ketamine?

Ketalar may cause a range of adverse reactions that vary in frequency and severity.

Common Side Effects: - Hypertension: transient increase in blood pressure. - Tachycardia: elevated heart rate. - Nausea: feeling of sickness. - Vomiting: expulsion of stomach contents. - Dissociation: sense of detachment from reality. - Salivation: increased oral secretions.

Serious or Rare Side Effects: - Respiratory depression: reduced breathing effort requiring support. - Psychotomimetic reactions: hallucinations, agitation, or severe confusion. - Cardiac arrhythmias: abnormal heart rhythms that may be life‑threatening.

What precautions apply to Ketamine?

When using Ketalar, clinicians should observe several safety measures.

Assess cardiovascular status: monitor blood pressure and heart rate before administration. Screen for psychiatric history: avoid in patients with uncontrolled psychosis. Avoid concurrent CNS depressants: risk of additive respiratory depression. Use in controlled setting: ensure airway management equipment is available. Store at 2-8°C: keep refrigerated, protect from light, do not freeze or shake.

What does Ketamine interact with?

Ketalar can interact with other medications, requiring careful management.

Major Interactions (Avoid): - Benzodiazepines: additive sedation and respiratory depression. - Opioids: increased risk of respiratory depression. - Monoamine oxidase inhibitors: potential hypertensive crisis.

Moderate Interactions (Monitor Closely): - Alcohol: enhanced central nervous system depression. - Sympathomimetic agents: may exacerbate hypertension. - Anticholinergics: may increase intraocular pressure.

Frequently asked questions

What is Ketalar used for?+
Ketalar contains ketamine and is used primarily for the induction and maintenance of general anesthesia, procedural sedation, and analgesia in acute pain situations. In some clinical settings it is also employed off‑label as a rapid‑acting adjunct for patients with treatment‑resistant depression.
How does ketamine work in the body?+
Ketamine blocks the NMDA receptor, a key component of excitatory neurotransmission, leading to dissociative anesthesia. Its additional actions on opioid receptors, monoamine pathways, and calcium channels contribute to analgesic effects and, at sub‑anesthetic doses, to rapid antidepressant responses.
What is the usual dose of Ketalar?+
The dose of Ketalar is determined by the prescribing clinician based on the patient’s age, weight, clinical condition, and the intended route (intravenous or intramuscular). Specific dosing regimens are individualized and should follow institutional protocols and the prescriber’s judgment.
Is Ketalar safe during pregnancy or breastfeeding?+
Ketamine crosses the placenta and is excreted in breast milk, so its safety in pregnancy and lactation has not been fully established. Use is generally reserved for situations where the potential benefit outweighs potential risks, and it should be prescribed only after careful risk assessment by a qualified healthcare professional.
How do I order Ketalar from GNH USA?+
To order Ketalar, submit an enquiry on the product page at gnh-usa.com, specifying the required quantity. GNH USA supplies hospitals, pharmacies and procurement teams worldwide, and will request verification of trade or institutional credentials. The sales team then provides pricing, availability, shipping details (including cold‑chain handling if required) and assists with import documentation.
How does Ketalar compare with other anesthetic agents?+
Ketalar differs from traditional inhalational or opioid‑based anesthetics by providing dissociative anesthesia through NMDA antagonism, which results in rapid onset and preservation of airway reflexes at sub‑anesthetic doses. Compared with agents like propofol, ketamine maintains cardiovascular stability but may produce psychotomimetic side effects that require monitoring.
What are the storage and handling requirements for Ketalar?+
Ketalar should be stored at 2‑8 °C in a refrigerator, protected from light, and must not be frozen or shaken. Keep the vial in its original packaging until use, and discard any solution that appears discolored or contains particles.
How is Ketalar administered to patients?+
Ketalar is supplied as an injectable solution and can be given intravenously or intramuscularly. Administration is performed by qualified healthcare professionals in a controlled environment, with dosing titrated to achieve the desired depth of anesthesia or sedation while continuously monitoring vital signs.
What are the most serious risks associated with Ketalar?+
The most serious risks include respiratory depression, severe hypertension, and psychotomimetic reactions such as hallucinations or agitation. Cardiac arrhythmias may also occur, especially in patients with pre‑existing heart disease. Immediate medical intervention and airway support are essential if these events arise.
Who should not receive Ketalar?+
Ketalar is contraindicated in patients with known hypersensitivity to ketamine or any component of the formulation. It should be avoided in individuals with uncontrolled severe hypertension, recent myocardial infarction, severe heart failure, or active psychosis, unless the benefits clearly outweigh the risks and appropriate monitoring is available.
Information provided on this page is for educational use by procurement and clinical professionals. Always consult a licensed healthcare provider for medical advice and prescribing decisions. GNH USA supplies this product subject to applicable regulatory and licensing requirements.

Product details

Drug
Ketamine
Route
Intramuscular Use , Intravenous Use
Manufacturer
Pfizer As
Origin
EU

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