GNH USA

Europe — EMA

Kestox

GNH USA supplies Kestox (Ebastine), a second‑generation H1 antihistamine for allergic rhinitis and chronic urticaria. Request a quote for global supply.

Ebastine

Request sourcing

1
Pack/s

What is Ebastine?

Ebastine, the active ingredient in Kestox, is a second‑generation H1 antihistamine presented as a unknown strength/unknown form for oral use. It treats allergic rhinitis and chronic urticaria in adults and adolescents, providing relief from nasal congestion, itching, sneezing and skin wheals. GNH USA supplies Kestox as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

What is Ebastine used for?

Ebastine is a second‑generation H1 antihistamine used to manage allergic conditions.

Allergic rhinitis: relief of nasal congestion, sneezing, itching and rhinorrhea. Chronic urticaria: reduction of wheal formation and itching. Allergic conjunctivitis: alleviation of eye itching and tearing.

What are the side effects of Ebastine?

Adverse reactions may occur with any antihistamine therapy.

Common Side Effects: - Headache: mild to moderate intensity. - Dry mouth: sensation of oral dryness. - Somnolence: occasional drowsiness. - Fatigue: general tiredness. - Nausea: mild gastrointestinal upset. - Dizziness: transient light‑headedness.

Serious or Rare Side Effects: - Cardiac arrhythmia: irregular heart rhythm. - Severe skin reactions: such as Stevens‑Johnson syndrome. - Hepatic enzyme elevation: abnormal liver function tests. - Anaphylaxis: acute allergic reaction requiring emergency care.

What precautions apply to Ebastine?

Before initiating therapy, consider the following safety points.

Pregnancy: consult a healthcare professional before use. Breastfeeding: evaluate risk versus benefit with a physician. Elderly patients: monitor for increased sedation. Drug interactions: avoid concurrent strong CYP3A4 inhibitors. Renal or hepatic impairment: dose adjustment may be required. Store at ambient temperature: keep in the original pack, protect from moisture.

What does Ebastine interact with?

Ebastine may interact with several medicines; monitoring is advised.

Major Interactions (Avoid): - Ketoconazole: may increase plasma concentrations of ebastine. - Erythromycin: can raise ebastine levels, enhancing side effects. - Ritonavir: may significantly elevate ebastine exposure.

Moderate Interactions (Monitor Closely):\n- Theophylline: potential increase in theophylline side effects. - Alcohol: may enhance sedative effects. - Other antihistamines: additive sedation may occur.

Frequently asked questions

What is Kestox used for?+
Kestox contains ebastine, a second‑generation H1 antihistamine indicated for the symptomatic relief of allergic rhinitis and chronic urticaria. It helps reduce nasal congestion, sneezing, itching, and skin wheals associated with these allergic conditions.
How does ebastine work?+
Ebastine selectively blocks peripheral H1 receptors, preventing histamine from binding and activating the allergic cascade. This inhibition reduces vasodilation, vascular permeability, and sensory nerve stimulation, thereby alleviating typical allergy symptoms without significant central nervous system effects.
What is the usual dose of Kestox?+
The dosage of Kestox is determined by the prescribing clinician based on the patient’s age, severity of symptoms, and overall health status. Healthcare professionals follow local prescribing guidelines to select an appropriate dose for each individual.
Is Kestox safe during pregnancy or breastfeeding?+
Safety data for ebastine in pregnancy and lactation are limited. Women who are pregnant, planning to become pregnant, or breastfeeding should discuss potential risks and benefits with their healthcare provider before using Kestox.
How do I order Kestox from GNH USA?+
To place an order, submit an enquiry on the Kestox product page at gnh-usa.com, specifying the required quantity. GNH USA works with hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.
How does Kestox compare with other antihistamines?+
Compared with first‑generation antihistamines, ebastine (Kestox) offers similar efficacy for allergy relief but with a lower risk of sedation and anticholinergic effects because it does not readily cross the blood‑brain barrier. This makes it preferable for patients who need to avoid drowsiness.
How should Kestox be stored and handled?+
Kestox should be stored at ambient temperature, below 25 °C, in its original packaging to protect it from moisture and light. Keep the product out of reach of children and avoid storing it in humid environments such as bathrooms.
How is Kestox administered?+
Kestox is taken orally. The tablet (or capsule) should be swallowed whole with a glass of water, preferably with or without food as directed by the prescriber. Do not crush, chew, or split the dosage form unless specifically instructed.
What are the most serious risks associated with Kestox?+
Serious adverse events, although rare, include cardiac arrhythmias, severe skin reactions such as Stevens‑Johnson syndrome, significant liver enzyme elevations, and anaphylaxis. Patients should seek immediate medical attention if they experience symptoms like chest pain, rash, swelling, or difficulty breathing.
Who should not use Kestox?+
Kestox is contraindicated in individuals with known hypersensitivity to ebastine or any of the tablet’s excipients. Caution is also advised for patients with severe hepatic impairment, uncontrolled cardiac disease, or those taking prohibited interacting medications.
Information provided on this page is for educational use by procurement and clinical professionals. Always consult a licensed healthcare provider for medical advice and prescribing decisions. GNH USA supplies this product subject to applicable regulatory and licensing requirements.
Send a sourcing enquiry for this product →

Product details

Drug
Ebastine
Route
Oral Use
Manufacturer
Oy Verman Ab
Origin
EU

Related products

A

A

Liquid Extract From Viscum Album Subsp. Abietis Var Abies Alba (1:20), Extraction Solvents: Water Fo

Helixor Heilmittel Gmbh
EU
A

A

Liquid Extract From Viscum Album Subsp. Abietis Var Abies Alba (1:20), Extraction Solvents: Water Fo

Helixor Heilmittel Gmbh
EU
A

A

Liquid Extract From Viscum Album Subsp. Abietis Var Abies Alba (1:20), Extraction Solvents: Water Fo

Helixor Heilmittel Gmbh
EU
A

A

Liquid Extract From Viscum Album Subsp. Abietis Var Abies Alba (1:20), Extraction Solvents: Water Fo

Helixor Heilmittel Gmbh
EU