Keronac

Diclofenac sodium, the active ingredient in Keronac, is a nonsteroidal anti-inflammatory drug presented as a topical gel for cutaneous use. It reduces pain and inflammation in musculoskeletal conditions.

GNH USA supplies Keronac as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Diclofenac sodium is used to manage pain and inflammation in musculoskeletal disorders.

- Osteoarthritis of the knee: relief of joint pain and reduction of inflammation. - Acute muscle sprain: alleviation of localized pain and swelling. - Tendinitis: decrease in tendon inflammation and associated discomfort. - Bursitis: mitigation of bursae swelling and pain. - Low back pain: short‑term reduction of lumbar discomfort.

Topical diclofenac can cause a range of skin‑related and systemic reactions.

Common Side Effects: - Skin irritation: mild redness or discomfort at the application site. - Burning sensation: transient warmth or stinging after use. - Itching: localized pruritus. - Dry skin: occasional flaking or dryness. - Rash: mild erythematous eruption. - Photosensitivity: increased sensitivity to sunlight.

Serious or Rare Side Effects: - Severe allergic reactions: angioedema, anaphylaxis, or Stevens‑Johnson syndrome. - Liver toxicity: elevated liver enzymes or hepatitis. - Cardiovascular events: increased risk of thrombotic events. - Gastrointestinal ulceration: rare systemic ulcer formation. - Severe skin reactions: necrotizing fasciitis or bullous dermatitis. - Systemic toxicity: renal impairment or hematologic abnormalities.

When using Keronac, consider the following safety measures.

- Avoid use on infected or broken skin: may worsen infection. - Do not apply to open wounds: risk of systemic absorption. - Limit application area: adhere to prescribed surface size. - Review anticoagulant therapy: increased bleeding potential. - Pregnancy and breastfeeding: discuss risks with a healthcare professional. - Store at room temperature: keep in the original pack, protect from moisture and light.

Diclofenac sodium may interact with several drug classes.

Major Interactions (Avoid): - Anticoagulants (e.g., warfarin): heightened bleeding risk. - Other NSAIDs: additive gastrointestinal toxicity. - Lithium: possible increase in serum lithium levels. - Methotrexate: enhanced methotrexate toxicity. - Selective COX‑2 inhibitors: combined cardiovascular risk.

Moderate Interactions (Monitor Closely):\n- ACE inhibitors: potential renal function changes. - Diuretics: possible reduction in antihypertensive effect. - Corticosteroids: increased risk of ulceration. - SSRIs: additive bleeding tendency.