Keral

Dexketoprofen, the active ingredient in Keral, is a nonsteroidal anti-inflammatory drug (NSAID) presented as an oral formulation for oral use. It is indicated for mild to moderate pain, musculoskeletal pain, post‑operative pain and dysmenorrhea in adult patients. GNH USA supplies Keral as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Dexketoprofen acts as an NSAID to relieve pain and inflammation in several common conditions. - Mild to moderate pain: provides rapid analgesia for everyday pain. - Musculoskeletal pain: reduces discomfort from strains, sprains and arthritis. - Post‑operative pain: helps control pain after surgical procedures. - Dysmenorrhea: alleviates menstrual cramps and associated discomfort.

Dexketoprofen may cause a range of adverse reactions, from mild to serious.

Common Side Effects: - Nausea: occasional feeling of sickness. - Dyspepsia: upset stomach or indigestion. - Headache: mild to moderate head pain. - Dizziness: transient light‑headedness. - Abdominal pain: discomfort in the stomach area. - Diarrhoea: loose stools.

Serious or Rare Side Effects: - Gastrointestinal ulcer or bleeding: potentially severe stomach bleeding. - Cardiovascular events: increased risk of heart attack or stroke. - Renal impairment: reduced kidney function. - Severe skin reactions: such as Stevens‑Johnson syndrome. - Hepatic dysfunction: liver enzyme abnormalities. - Anaphylaxis: life‑threatening allergic reaction.

When prescribing or dispensing Dexketoprofen, consider the following safety measures. - Assess renal function: adjust use in patients with kidney impairment. - Assess hepatic function: caution in liver disease. - Avoid in known hypersensitivity: do not use if the patient is allergic to NSAIDs. - Use with caution in the elderly: higher risk of gastrointestinal complications. - Monitor cardiovascular risk: avoid in uncontrolled hypertension or known heart disease. - Store at room temperature: keep in the original pack, protect from moisture.

Dexketoprofen can interact with several drug classes, requiring careful management.

Major Interactions (Avoid): - Anticoagulants (e.g., warfarin): increased bleeding risk. - Other NSAIDs or COX‑2 inhibitors: additive gastrointestinal toxicity. - Selective serotonin reuptake inhibitors (SSRIs): heightened bleeding tendency.

Moderate Interactions (Monitor Closely): - Diuretics: possible reduction in renal function. - Methotrexate: decreased clearance leading to toxicity.