Keraflox

Prulifloxacin, the active ingredient in Keraflox, is a fluoroquinolone presented as an oral tablet for oral use. It provides broad‑spectrum antibacterial activity and is indicated for the treatment of urinary tract infections, respiratory tract infections, and skin and soft‑tissue infections in adult patients, with dosage determined by the prescribing clinician.

GNH USA supplies Keraflox as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies, transplant centres and clinics worldwide, ensuring consistent quality, regulatory compliance, and reliable logistics for global distribution.

Prulifloxacin is used to treat bacterial infections affecting several organ systems.

- Urinary tract infection: effective in eradicating susceptible bacteria causing cystitis and pyelonephritis. - Respiratory tract infection: treats community‑acquired pneumonia and acute exacerbations of chronic bronchitis. - Skin and soft‑tissue infection: clears infections such as cellulitis, abscesses and wound infections caused by susceptible organisms.

Prulifloxacin may cause a range of adverse reactions.

Common Side Effects: - Nausea: mild to moderate stomach upset. - Diarrhea: loose stools, sometimes watery. - Headache: transient cranial discomfort. - Rash: mild skin erythema or itching.

Serious or Rare Side Effects: - Tendon rupture: especially in the Achilles tendon, may occur without warning. - QT interval prolongation: can predispose to cardiac arrhythmias. - Severe allergic reactions: including anaphylaxis, angioedema, or Stevens‑Johnson syndrome.

Prulifloxacin should be used with caution in specific clinical situations.

- Renal impairment: monitor renal function and adjust therapy as needed. - Hypersensitivity: avoid in patients with known allergy to fluoroquinolones. - Elderly patients: increased risk of tendon injury; advise against sudden strenuous activity. - Concomitant QT‑prolonging drugs: assess cardiac risk before co‑administration. - Store at room temperature: keep in the original packaging, protect from moisture and direct sunlight.

Prulifloxacin can interact with other medicines, requiring attention to potential effects.

Major Interactions (Avoid): - Antacids containing magnesium or aluminum: may markedly reduce prulifloxacin absorption. - Warfarin: can enhance anticoagulant effect, increasing bleeding risk. - Systemic corticosteroids: may increase the likelihood of tendon rupture.

Moderate Interactions (Monitor Closely): - NSAIDs: may increase central nervous system stimulation. - Theophylline: plasma concentrations may rise, risking toxicity. - Diabetes medications: possible alteration of glycemic control.