Keol (Oxygen)

Oxygen, the active ingredient in Keol, is a Medical gas presented as a medical gas for inhalation use. It provides supplemental oxygen to patients with hypoxemia, respiratory distress, COPD exacerbations and those requiring post‑operative oxygen therapy.

GNH USA supplies Keol as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, transplant centres, oncology centres, pharmacies and clinics worldwide.

Keol is used in respiratory therapy to improve oxygenation in several clinical conditions.

Hypoxemia: Increases arterial oxygen tension to correct low blood‑oxygen levels. Respiratory distress: Supplies additional oxygen to relieve acute breathing difficulty. COPD exacerbations: Supports patients during flare‑ups to maintain adequate oxygen saturation. Post‑operative oxygen therapy: Provides supplemental oxygen after surgery to promote recovery and prevent hypoxia.

Supplemental oxygen can be associated with both frequent and rare adverse reactions.

Common Side Effects: - Nasal dryness or irritation - Headache - Cough or throat discomfort - Dizziness or light‑headedness - Fatigue - Mild nausea

Serious or Rare Side Effects: - Oxygen toxicity leading to lung injury - Seizures in high‑concentration exposure - Fire or explosion hazard if exposed to ignition sources - Retinal damage in premature infants (retinopathy of prematurity) - Severe hypercapnia in patients with chronic CO₂ retention

Oxygen therapy requires careful assessment and monitoring to ensure safety. - Assess need: Confirm indication and target oxygen saturation before initiating therapy. - Monitor: Continuously check SpO₂ and adjust flow rates as needed. - Hypercapnia risk: Avoid in patients with CO₂ retention unless ventilatory support is provided. - Delivery device: Use appropriate cannula or mask to prevent mucosal injury. - Fire safety: Keep away from open flames, smoking materials, and combustible gases. - Store at ambient temperature: Keep cylinders in a well‑ventilated, dry area away from heat and ignition sources.

Oxygen can interact with certain substances, influencing safety and efficacy.

Major Interactions (Avoid): - Flammable gases (e.g., methane, propane): Increased fire and explosion risk. - Nitrous oxide: Potentiates fire hazard when used concurrently.

Moderate Interactions (Monitor Closely): - Carbon monoxide: Impairs oxygen delivery; monitor for CO exposure. - Sedative agents (e.g., benzodiazepines, opioids): May deepen respiratory depression; observe respiratory status. - Bronchodilators: May enhance bronchodilation; adjust dosing if needed.