GNH USA

Europe — EMA

Kelzy

GNH USA supplies Kelzy (Dienogest/Ethinylestradiol), a combined oral contraceptive for prevention of pregnancy. Request a quote for global supply today.

Dienogest, Ethinylestradiol | Lactose

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What is Dienogest, Ethinylestradiol | Lactose?

Dienogest/Ethinylestradiol, the active ingredient in Kelzy, is a combined oral contraceptive presented as a tablet for oral use. It prevents pregnancy in women of reproductive age by regulating hormonal cycles. The formulation contains a synthetic progestogen (dienogest) and an estrogen (ethinylestradiol) that work together to inhibit ovulation and create an unfavorable environment for fertilisation. GNH USA supplies Kelzy as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide with consistent quality and regulatory compliance.

What is Dienogest, Ethinylestradiol | Lactose used for?

Kelzy, a combined oral contraceptive, is indicated for several reproductive‑health applications. - Contraception: Prevents pregnancy by inhibiting ovulation and altering cervical mucus. - Menstrual cycle regulation: Provides predictable withdrawal bleeding and reduces cycle irregularities. - Moderate acne treatment: Improves acne lesions through hormonal regulation in women.

What are the side effects of Dienogest, Ethinylestradiol | Lactose?

Kelzy may cause a range of adverse reactions, which are grouped by frequency and severity.

Common Side Effects: - Nausea: mild to moderate stomach upset. - Headache: tension‑type or migraine‑like pain. - Breast tenderness: swelling or discomfort. - Breakthrough bleeding: spotting between periods.

Serious or Rare Side Effects: - Venous thromboembolism: deep‑vein thrombosis or pulmonary embolism. - Hypertensive crisis: sudden high‑blood‑pressure episodes. - Liver dysfunction: jaundice or abnormal liver enzymes.

What precautions apply to Dienogest, Ethinylestradiol | Lactose?

Before prescribing Kelzy, clinicians should evaluate the following safety considerations. - Contraindication: Do not use in women with known or suspected pregnancy. - Cardiovascular risk: Avoid in patients with history of thromboembolic disorders, stroke, or uncontrolled hypertension. - Smoking: Caution in women over 35 who smoke, as risk of cardiovascular events increases. - Liver disease: Use with caution in patients with active liver disease or impaired hepatic function. - Drug interactions: Review concomitant medications that may affect estrogen metabolism. - Store at ambient temperature: Keep below 25 °C in the original packaging, protected from moisture and light.

What does Dienogest, Ethinylestradiol | Lactose interact with?

Kelzy can interact with other medicines, altering its effectiveness or safety profile.

Major Interactions (Avoid): - Combined hormonal contraceptives with strong CYP3A4 inducers (e.g., rifampicin, carbamazepine) may reduce contraceptive efficacy. - Anticoagulants (warfarin) may have altered plasma levels when used with estrogen‑containing pills. - Certain antiretrovirals (e.g., efavirenz) can significantly decrease hormone concentrations.

Moderate Interactions (Monitor Closely): - Antifungal agents (ketoconazole, itraconazole) may increase estrogen levels, raising risk of side effects. - Selective serotonin reuptake inhibitors (SSRIs) may modestly affect platelet function. - Herbal supplements containing St. John’s wort can lower hormone levels.

Frequently asked questions

What is Kelzy used for?+
Kelzy is a combined oral contraceptive tablet that is primarily used to prevent pregnancy. In addition to contraception, it can be prescribed to regulate menstrual cycles and to treat moderate acne in women by providing hormonal balance.
How does Dienogest/Ethinylestradiol work?+
The combination contains dienogest, a synthetic progestogen, and ethinylestradiol, an estrogen. Ethinylestradiol suppresses the luteinising hormone surge, while dienogest reinforces this suppression, blocks ovulation, thickens cervical mucus and alters the endometrium, making fertilisation and implantation unlikely.
What is the usual dose of Kelzy?+
The dosing regimen for Kelzy is determined by the prescribing clinician. Typically, a combined oral contraceptive is taken once daily for 21 consecutive days followed by a 7‑day hormone‑free interval, but the exact schedule should be confirmed with the prescriber.
Is Kelzy safe during pregnancy or breastfeeding?+
Kelzy is contraindicated in pregnancy and should not be started or continued by women who are pregnant. While limited data exist for breastfeeding, most guidelines advise against using combined estrogen‑progestogen contraceptives during lactation because of potential effects on milk production and infant exposure.
How do I order Kelzy from GNH USA?+
To order Kelzy, submit an enquiry on the product page at gnh-usa.com specifying the required quantity. GNH USA supplies hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including any cold‑chain requirements) and necessary import documentation.
How does Kelzy compare with other combined oral contraceptives?+
Kelzy contains dienogest as the progestogen, which offers a slightly different side‑effect profile compared with older progestins such as levonorgestrel. Efficacy in preventing pregnancy is comparable across approved combined oral contraceptives, but the choice may depend on individual tolerance, acne benefits, and specific cardiovascular risk considerations.
How should Kelzy be stored and handled?+
Kelzy tablets should be stored at ambient temperature, preferably below 25 °C. Keep them in the original blister pack, protect from moisture and direct light, and ensure they are out of reach of children.
How is Kelzy administered?+
Kelzy is taken orally as a tablet. The recommended practice is to swallow one tablet each day at the same time, with or without food, for the prescribed cycle length. Missing a dose should be managed according to the prescribing information.
What are the most serious risks to watch for while using Kelzy?+
The most serious risks include venous thromboembolism (deep‑vein thrombosis or pulmonary embolism), arterial clot events such as stroke or myocardial infarction, severe hypertension, and liver dysfunction. Patients should seek immediate medical attention if they experience unexplained chest pain, severe headache, visual changes, or sudden swelling of the legs.
Who should not use Kelzy?+
Kelzy should not be used by women who are pregnant, have a known or suspected thromboembolic disorder, uncontrolled hypertension, active liver disease, breast cancer, or estrogen‑dependent tumors. It is also contraindicated in smokers over 35 years of age and in individuals with known hypersensitivity to any component of the tablet.
Information provided on this page is for educational use by procurement and clinical professionals. Always consult a licensed healthcare provider for medical advice and prescribing decisions. GNH USA supplies this product subject to applicable regulatory and licensing requirements.

Product details

Drug
Dienogest, Ethinylestradiol | Lactose
Route
Oral Use
Manufacturer
Exeltis Germany Gmbh
Origin
EU

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