Keforal

Cefalexin Monohydrate, the active ingredient in Keforal, is a cephalosporin presented as an oral tablet for oral use. It treats bacterial infections of the skin, respiratory tract, urinary system and bone in adult and pediatric patients. GNH USA supplies Keforal as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Keforal, a cephalosporin antibacterial, is used to treat infections caused by susceptible bacteria in several organ systems. - Skin and soft tissue infections: effective in treating bacterial infections of the skin and underlying tissues. - Respiratory tract infections: used for community‑acquired pneumonia, bronchitis and sinusitis caused by susceptible organisms. - Urinary tract infections: clears infections of the bladder and kidneys caused by susceptible strains. - Bone and joint infections: assists in managing osteomyelitis and septic arthritis when indicated.

Cefalexin Monohydrate may cause a range of adverse reactions, most of which are mild and reversible.

Common Side Effects: - Nausea: mild to moderate stomach upset. - Diarrhea: loose stools that may be watery. - Abdominal pain: cramping or discomfort in the stomach area. - Rash: mild skin redness or itching. - Headache: transient head pain. - Dizziness: occasional light‑headedness.

Serious or Rare Side Effects: - Anaphylaxis: severe allergic reaction with breathing difficulty. - Stevens‑Johnson syndrome: rare but serious skin disorder. - Clostridioides difficile‑associated diarrhea: severe colitis. - Blood dyscrasias: abnormal blood cell counts. - Hepatic enzyme elevation: potential liver function changes. - Renal impairment: reduced kidney function in susceptible individuals.

Before prescribing Keforal, clinicians should consider several safety aspects. - Assess renal function: adjust dose in patients with impaired kidney function. - Monitor for allergic reactions: discontinue if severe hypersensitivity occurs. - Use cautiously in gastrointestinal disease: risk of colitis may be higher. - Avoid in known cephalosporin hypersensitivity: contraindicated for those with prior reactions. - Consider pregnancy status: safety not established; weigh benefits against risks. - Store at ambient temperature: keep in the original pack, protect from moisture.

Cefalexin Monohydrate can interact with other medicines, affecting efficacy or safety.

Major Interactions (Avoid): - Probenecid: may increase cefalexin plasma levels, raising toxicity risk. - Warfarin: can enhance anticoagulant effect, leading to increased bleeding.

Moderate Interactions (Monitor Closely): - Oral contraceptives: may reduce hormonal efficacy, consider alternative contraception. - Allopurinol: combined use may increase rash incidence. - Aminoglycosides: additive nephrotoxicity potential. - Diuretics: may alter renal clearance of cefalexin.