Keforal

Cefalexin, the active ingredient in Keforal, is a first‑generation cephalosporin presented as an oral dosage form for oral administration. It is used to treat a range of bacterial infections, including skin and soft‑tissue infections, respiratory tract infections, urinary tract infections and bone and joint infections in both adults and children when prescribed by a healthcare professional.

GNH USA supplies Keforal as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide, with a focus on quality assurance and regulatory compliance.

Cefalexin is a broad‑spectrum antibiotic that targets bacterial cell wall synthesis, making it effective for several common infection types.

- Skin and soft tissue infections: reduces bacterial load and promotes healing of infected skin lesions. - Respiratory tract infections: eradicates causative bacteria in conditions such as bronchitis and pneumonia. - Urinary tract infections: eliminates uropathogens responsible for cystitis and pyelonephritis. - Bone and joint infections: assists in clearing bacterial involvement in osteomyelitis and septic arthritis.

Cefalexin may cause a range of adverse reactions, from mild to severe.

Common Side Effects: - Nausea: mild stomach upset that may resolve without intervention. - Diarrhea: increased bowel movements, occasionally watery. - Abdominal pain: cramping or discomfort in the stomach area. - Vomiting: expulsion of stomach contents. - Rash: skin redness or itching. - Headache: mild to moderate head discomfort.

Serious or Rare Side Effects: - Anaphylaxis: severe allergic reaction with breathing difficulty. - Clostridioides difficile‑associated diarrhea: severe colitis after antibiotic use. - Stevens‑Johnson syndrome: rare, life‑threatening skin disorder. - Blood dyscrasias: abnormal blood cell counts such as leukopenia. - Hepatic enzyme elevation: potential liver function changes. - Neutropenia: reduced neutrophil count increasing infection risk.

Before using Cefalexin, consider the following safety measures.

- Renal impairment: dose may need adjustment in patients with reduced kidney function. - History of penicillin allergy: assess cross‑reactivity before prescribing. - Pregnancy: use only if clearly needed after risk‑benefit evaluation. - Concurrent oral contraceptives: may reduce contraceptive efficacy; consider additional methods. - Prolonged therapy: monitor for superinfection or fungal overgrowth. - Store at room temperature: keep in the original container, protect from moisture and light.

Cefalexin can interact with other medicines, requiring attention to avoid adverse outcomes.

Major Interactions (Avoid): - Probenecid: may increase cefalexin plasma levels, raising toxicity risk. - Warfarin: can enhance anticoagulant effect, increasing bleeding risk.

Moderate Interactions (Monitor Closely): - Oral contraceptives: may reduce hormonal effectiveness. - Allopurinol: may increase the likelihood of rash. - Aminoglycosides: combined use may add nephrotoxic potential.