Keforal

Cefalexin, the active ingredient in Keforal, is a cephalosporin presented as an oral tablet for oral use. It treats bacterial infections of the skin, respiratory tract, urinary system and bone in adults and children when prescribed by a healthcare professional.

GNH USA supplies Keforal as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide. The company follows strict quality standards to provide reliable sourcing for global healthcare providers and ensures compliance with regulatory requirements through robust manufacturing and distribution networks.

Cefalexin is a broad‑spectrum cephalosporin antibiotic used to treat bacterial infections in various organ systems.

Skin and soft tissue infections: effective for cellulitis, impetigo and wound infections. Respiratory tract infections: treats community‑acquired pneumonia, sinusitis and bronchitis caused by susceptible organisms. Urinary tract infections: used for cystitis and pyelonephritis caused by susceptible bacteria. Bone and joint infections: employed in osteomyelitis and septic arthritis when indicated.

Cefalexin may cause a range of adverse reactions, most of which are mild and reversible.

Common Side Effects: - Nausea - Diarrhea - Abdominal pain - Vomiting - Rash - Headache

Serious or Rare Side Effects: - Anaphylaxis or severe allergic reactions such as Stevens‑Johnson syndrome - Clostridioides difficile‑associated colitis - Hematologic abnormalities (e.g., neutropenia, thrombocytopenia) - Hepatic dysfunction - Renal impairment - Pseudomembranous colitis

Before prescribing cefalexin, clinicians should consider several precautionary measures to minimize risk.

Renal impairment: adjust dose or monitor renal function. Hepatic disease: use with caution in patients with liver dysfunction. Allergy: avoid in patients with known hypersensitivity to cephalosporins or penicillins. Pregnancy and lactation: evaluate risk‑benefit and consult obstetric guidance. Drug interactions: review concomitant medications that may affect cefalexin levels or toxicity. Store at ambient temperature below 25°C: keep in the original packaging, protect from moisture and light.

Cefalexin can interact with other medicines, altering its effectiveness or increasing toxicity.

Major Interactions (Avoid): - Probenecid: may increase cefalexin plasma concentrations leading to toxicity. - Live bacterial vaccines: concurrent use may reduce vaccine efficacy and increase infection risk.

Moderate Interactions (Monitor Closely): - Warfarin: cefalexin may potentiate anticoagulant effect; monitor INR. - Oral contraceptives: reduced plasma levels may decrease contraceptive efficacy; advise additional measures. - Aminoglycosides: combined nephrotoxic potential; monitor renal function.