Keflex (Cefalexin Monohydrate)

Cefalexin, the active ingredient in Keflex, is a cephalosporin presented as an oral dosage form for oral use. It treats bacterial infections of the skin, respiratory tract, urinary tract, and bone and joint in adults and children as prescribed.

GNH USA supplies Keflex as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Keflex is a cephalosporin antibiotic that targets a range of bacterial infections. - Skin and soft tissue infections: resolves bacterial infection and reduces inflammation. - Respiratory tract infections: treats community‑acquired pneumonia, sinusitis and related conditions. - Urinary tract infections: eradicates causative bacteria in the urinary system. - Bone and joint infections: assists in treating osteomyelitis and related infections.

Common Side Effects: - Nausea: mild stomach upset. - Diarrhea: loose stools, usually self‑limiting. - Vomiting: occasional emesis. - Abdominal pain: cramping or discomfort. - Rash: mild skin redness or itching. - Headache: transient head discomfort.

Serious or Rare Side Effects: - Anaphylaxis: severe allergic reaction with breathing difficulty. - Clostridioides difficile‑associated diarrhea: severe colitis. - Stevens‑Johnson syndrome: serious skin blistering. - Serum sickness: fever, joint pain, rash. - Hemolytic anemia: breakdown of red blood cells. - Elevated liver enzymes: potential liver inflammation.

Before using Keflex, consider the following precautions: - Assess renal function: adjust dose in renal impairment. - Monitor for allergic reactions: discontinue if severe rash or anaphylaxis occurs. - Use with caution in gastrointestinal disease: may exacerbate symptoms. - Avoid in patients with known hypersensitivity to cephalosporins. - Review concomitant medications: potential for drug interactions. - Store at room temperature: keep in the original pack, protect from moisture.

Keflex may interact with several medicines.

Major Interactions (Avoid): - Probenecid: may increase cefalexin plasma levels. - Warfarin: can enhance anticoagulant effect, increasing bleeding risk. - Live bacterial vaccines: may reduce vaccine efficacy.

Moderate Interactions (Monitor Closely): - Oral contraceptives: may reduce hormonal effectiveness. - Loop diuretics: may increase risk of nephrotoxicity. - Aminoglycosides: combined use may heighten renal toxicity.