GNH USA

Europe — EMA

Keflex

GNH USA supplies Keflex (Cefalexin), a cephalosporin antibiotic for skin, respiratory, urinary and bone infections. Request a quote for global supply.

Cefalexin

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What is Cefalexin?

Cefalexin, the active ingredient in Keflex, is a cephalosporin presented as an oral tablet for oral use. It treats bacterial infections of the skin, respiratory tract, urinary tract and bone in both adults and children.

GNH USA supplies Keflex as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

What is Cefalexin used for?

Cefalexin is a broad‑spectrum cephalosporin used to treat infections caused by susceptible bacteria.

- Skin and soft tissue infections: effective for cellulitis, impetigo and wound infections. - Respiratory tract infections: treats acute bacterial sinusitis, tonsillitis and community‑acquired pneumonia. - Urinary tract infections: clears uncomplicated cystitis and pyelonephritis. - Bone infections: used in osteomyelitis caused by susceptible organisms.

What are the side effects of Cefalexin?

Cefalexin may cause a range of adverse reactions, most of which are mild and reversible.

Common Side Effects: - Diarrhea: loose stools occurring during therapy. - Nausea: feeling of stomach upset. - Rash: mild skin erythema or itching. - Elevated liver enzymes: transient increase in hepatic transaminases.

Serious or Rare Side Effects: - Anaphylaxis: severe, potentially life‑threatening allergic reaction. - Clostridioides difficile colitis: severe inflammation of the colon. - Hemolytic anemia: destruction of red blood cells leading to fatigue and pallor.

What precautions apply to Cefalexin?

Before prescribing Cefalexin, clinicians should consider several safety aspects.

- Assess renal function: adjust dose in patients with impaired clearance. - Review allergy history: avoid in individuals with known cephalosporin or penicillin hypersensitivity. - Monitor hepatic enzymes: watch for significant elevations during prolonged use. - Caution in pregnancy: limited data; weigh benefits against potential risks. - Store at ambient temperature: keep below 25 °C, retain in original packaging, protect from moisture.

What does Cefalexin interact with?

Cefalexin can interact with other medicines, altering efficacy or safety.

Major Interactions (Avoid): - Probenecid: may increase cefalexin plasma concentrations, raising toxicity risk. - Oral anticoagulants (e.g., warfarin): potential enhancement of anticoagulant effect.

Moderate Interactions (Monitor Closely): - Metformin: reduced renal clearance may require dose adjustment. - Oral contraceptives: possible reduction in contraceptive effectiveness. - Aminoglycosides: concurrent use may increase nephrotoxicity risk.

Frequently asked questions

What is Keflex used for?+
Keflex contains cefalexin, a cephalosporin antibiotic prescribed to treat bacterial infections of the skin, respiratory tract, urinary system and bone. It is effective against susceptible Gram‑positive and some Gram‑negative organisms and is used in both adult and pediatric patients.
How does cefalexin work?+
Cefalexin works by binding to penicillin‑binding proteins on bacterial cell walls, inhibiting the cross‑linking of peptidoglycan strands. This disruption weakens the cell wall, causing osmotic instability and ultimately leading to bacterial cell death.
What is the usual dose of Keflex?+
The dosage of Keflex is determined by the prescribing clinician based on the type and severity of infection, patient age, weight and renal function. Healthcare professionals tailor the regimen to achieve optimal therapeutic outcomes.
Is Keflex safe during pregnancy or breastfeeding?+
Safety data for cefalexin in pregnancy are limited, and the drug is classified as pregnancy category unknown. It should only be used when the potential benefit justifies any possible risk to the fetus. Breastfeeding mothers should consult a healthcare provider, as small amounts may be excreted in milk.
How do I order Keflex from GNH USA?+
To order Keflex, submit an enquiry on the product page at gnh-usa.com, specifying the required quantity. GNH USA supplies hospitals, pharmacies and procurement teams worldwide, and will request trade or institutional credentials before providing pricing, availability, shipping details and any necessary import documentation.
How does Keflex compare with other antibiotics?+
Compared with penicillins, cefalexin offers a broader spectrum against certain Gram‑positive organisms and better resistance to β‑lactamase enzymes. It is often chosen when patients have mild penicillin allergies or when the infecting organism is known to be susceptible to cephalosporins.
How should Keflex be stored and handled?+
Keflex tablets should be stored at ambient temperature, below 25 °C, in their original container to protect from moisture. Keep the product out of reach of children and avoid exposure to direct sunlight or excessive humidity.
How is Keflex administered?+
Keflex is administered orally, typically as a tablet taken with or without food as directed by a healthcare professional. The exact timing and frequency depend on the prescribed regimen and the specific infection being treated.
What are the most serious risks associated with Keflex?+
Serious risks include severe allergic reactions such as anaphylaxis, Clostridioides difficile‑associated colitis, and rare hematologic events like hemolytic anemia. Patients should seek immediate medical attention if they experience symptoms such as difficulty breathing, severe diarrhea, or unexplained fatigue.
Who should not use Keflex?+
Keflex should be avoided in individuals with a known hypersensitivity to cefalexin, other cephalosporins, or penicillins. Caution is also advised for patients with significant renal impairment, as dose adjustment may be required.
Information provided on this page is for educational use by procurement and clinical professionals. Always consult a licensed healthcare provider for medical advice and prescribing decisions. GNH USA supplies this product subject to applicable regulatory and licensing requirements.
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Product details

Drug
Cefalexin
Route
Oral Use
Manufacturer
Teva B.V
Origin
EU

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