Kayexalate Calcium

Calcium Polystyrene Sulfonate, the active ingredient in Kayexalate Calcium, is a cation exchange resin presented as a powder for oral and rectal use. It binds potassium in the gastrointestinal tract and is used to treat hyperkalemia in patients with elevated serum potassium levels.

GNH USA supplies Kayexalate Calcium as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, transplant centres, oncology centres, pharmacies and clinics worldwide.

Kayexalate Calcium is a potassium‑binding resin used in the management of conditions characterized by excess potassium. - Hyperkalemia (acute): lowers serum potassium to safe levels. - Hyperkalemia (chronic): maintains long‑term potassium control. - Hyperkalemia in renal failure: provides potassium removal when kidney function is impaired.

Kayexalate Calcium may cause gastrointestinal and electrolyte‑related adverse reactions.

Common Side Effects: - Nausea: mild to moderate discomfort after ingestion. - Constipation: reduced bowel movements, may require laxatives. - Abdominal discomfort: cramping or pain in the stomach area. - Vomiting: occasional expulsion of stomach contents. - Diarrhea: loose stools in some patients. - Taste alteration: metallic or unpleasant taste.

Serious or Rare Side Effects: - Intestinal necrosis: severe bowel tissue damage, rare but serious. - Severe electrolyte disturbances: marked hypocalcemia or hypokalemia. - Bowel obstruction: blockage due to resin accumulation. - Gastrointestinal bleeding: rare hemorrhage in the GI tract.

When prescribing Kayexalate Calcium, clinicians should consider several safety measures. - Monitor serum potassium: check levels regularly to avoid over‑correction. - Assess renal function: reduced clearance may increase risk of hyperkalemia. - Review concomitant potassium‑sparing agents: avoid additive potassium load. - Caution in patients with bowel disorders: risk of obstruction or necrosis. - Avoid in severe hypercalcemia: calcium exchange may worsen calcium excess. - Store at ambient temperature: keep in the original pack, protect from moisture.

Kayexalate Calcium can interact with other medicines that affect potassium balance or gastrointestinal absorption.

Major Interactions (Avoid): - Oral potassium supplements: may negate the resin's effect. - ACE inhibitors or ARBs: increase risk of severe hypokalemia. - Potassium‑sparing diuretics (e.g., spironolactone): additive potassium elevation.

Moderate Interactions (Monitor Closely): - Digoxin: hypokalemia can heighten digoxin toxicity. - Insulin therapy: rapid potassium shifts may cause hypoglycemia. - Beta‑blockers: altered response to potassium changes.