GNH USA

Europe — EMA

Karbamid/Glycerol Aco (Glycerol, Urea)

GNH USA supplies Karbamid/Glycerol Aco (Urea & Glycerol), a dermatologic topical for dry skin, ichthyosis, keratosis pilaris and eczema.

Glycerol, Urea

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What is Glycerol, Urea?

Urea and Glycerol, the active ingredients in Karbamid/Glycerol Aco, are dermatologic agents presented as a topical preparation for cutaneous use. They help soften dry, scaly skin and improve hydration in conditions such as xerosis, ichthyosis, keratosis pilaris, and eczema.

GNH USA supplies Karbamid/Glycerol Aco as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

What is Glycerol, Urea used for?

Karbamid/Glycerol Aco is applied to the skin to manage disorders characterized by excessive dryness and keratin buildup. - Dry skin (xerosis): restores moisture and reduces scaling. - Ichthyosis: softens thickened plaques and improves skin texture. - Keratosis pilaris: smooths follicular bumps and lessens roughness. - Eczema: alleviates dryness and supports barrier function.

What are the side effects of Glycerol, Urea?

Topical application of Karbamid/Glycerol Aco may cause local reactions.

Common Side Effects: - Stinging or burning sensation at the application site. - Mild itching or irritation. - Transient redness. - Dryness or flaking after initial use. - Contact dermatitis in sensitive individuals.

Serious or Rare Side Effects: - Severe allergic reaction (e.g., swelling, hives, difficulty breathing). - Persistent skin ulceration or erosions. - Widespread rash or bullous formation. - Secondary infection of compromised skin. - Unusual discoloration of the skin.

What precautions apply to Glycerol, Urea?

Before using Karbamid/Glycerol Aco, consider the following precautions. - Assess skin integrity: avoid on open wounds or infected areas. - Test for sensitivity: apply a small amount to a limited area first. - Combine with other keratolytics cautiously to prevent excessive irritation. - Use under medical supervision in pediatric or elderly patients. - Discontinue if severe irritation or allergic signs develop. - Store at ambient temperature: keep in original container, protect from moisture and direct sunlight.

What does Glycerol, Urea interact with?

Karbamid/Glycerol Aco has limited systemic interactions, but topical co‑applications may affect tolerability.

Major Interactions (Avoid): - Concurrent use with strong topical steroids or other potent keratolytics may cause severe irritation. - Application over areas treated with chemical peels can exacerbate skin damage.

Moderate Interactions (Monitor Closely): - Use with occlusive dressings may increase absorption and irritation risk. - Combining with other moisturizers containing alcohol could enhance drying effects. - Co‑application with topical antibiotics should be monitored for potential sensitization.

Frequently asked questions

What conditions is Karbamid/Glycerol Aco used for?+
Karbamid/Glycerol Aco is a topical formulation containing urea and glycerol that is used to manage dry skin conditions such as xerosis, ichthyosis, keratosis pilaris, and mild to moderate eczema. It works by softening thickened skin and improving hydration, helping to reduce scaling, roughness, and discomfort associated with these dermatologic disorders.
How does urea and glycerol work in this product?+
Urea acts as a keratolytic, breaking down excess keratin and facilitating the shedding of dry, scaly skin. Glycerol is a humectant that draws water into the outer skin layer, increasing moisture content and enhancing barrier function. Together they provide both exfoliation and hydration, leading to smoother, more supple skin.
What is the usual dose of Karbamid/Glycerol Aco?+
The appropriate amount and frequency of application are determined by the prescribing healthcare professional based on the severity of the skin condition, patient age, and treatment response. Typically, a thin layer is applied to the affected area once or twice daily, but exact instructions should follow the prescriber’s guidance.
Is Karbamid/Glycerol Aco safe during pregnancy or breastfeeding?+
There is limited specific data on the use of topical urea‑glycerol preparations during pregnancy or lactation. Because systemic absorption is minimal, it is generally considered low risk, but healthcare providers should evaluate the benefit‑risk ratio for each individual and advise accordingly.
How do I order Karbamid/Glycerol Aco from GNH USA?+
To place an order, submit an enquiry on the product page at gnh-usa.com, specifying the required quantity. GNH USA works with hospitals, pharmacies, and procurement teams worldwide, and will request verification of trade or institutional credentials. After confirmation, the sales team provides pricing, availability, shipping details (including any temperature requirements), and assists with import documentation.
How does Karbamid/Glycerol Aco compare with other moisturizers?+
Compared with simple emollients, Karbamid/Glycerol Aco combines a keratolytic (urea) with a humectant (glycerol), offering both exfoliation of hyperkeratotic skin and enhanced hydration. This dual action can be more effective for conditions like ichthyosis or keratosis pilaris, where ordinary moisturizers may not sufficiently soften thickened plaques.
What are the storage and handling requirements for this product?+
Store Karbamid/Glycerol Aco at ambient temperature, preferably below 25 °C. Keep the container tightly closed, protect it from moisture and direct sunlight, and avoid freezing. Ensure the packaging remains intact to maintain product stability.
How is Karbamid/Glycerol Aco applied?+
The product is applied topically to clean, dry skin. A thin layer should be spread over the affected area and gently massaged until absorbed. Frequency of application (once or twice daily) depends on the prescriber’s instructions and the severity of the skin condition.
What are the most serious risks associated with using Karbamid/Glycerol Aco?+
The most serious risks include severe allergic reactions such as anaphylaxis, extensive skin irritation leading to ulceration, and secondary infection of compromised skin. Users should discontinue the product and seek medical attention immediately if they experience swelling, difficulty breathing, widespread rash, or signs of infection.
Who should not use Karbamid/Glycerol Aco?+
Individuals with known hypersensitivity to urea, glycerol, or any excipients in the formulation should avoid using the product. It should also not be applied to open wounds, infected skin, or areas where a strong keratolytic or irritant is already in use without medical supervision.
Information provided on this page is for educational use by procurement and clinical professionals. Always consult a licensed healthcare provider for medical advice and prescribing decisions. GNH USA supplies this product subject to applicable regulatory and licensing requirements.
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Product details

Drug
Glycerol, Urea
Route
Cutaneous Use
Manufacturer
Aco Hud Nordic Ab
Origin
EU

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