GNH USA

Europe — EMA

Kantos Master

GNH USA supplies Kantos Master (Formoterol/Beclometasone), a combination inhaled corticosteroid and long‑acting β2‑agonist for asthma and COPD.

Formoterol Fumarate Dihydrate, Beclometasone Dipropionate Anhydrous

Request sourcing

1
Pack/s

What is Formoterol Fumarate Dihydrate, Beclometasone Dipropionate Anhydrous?

Formoterol fumarate and beclometasone dipropionate, the active ingredients in Kantos Master, are a combination inhaled corticosteroid and long‑acting β2‑agonist presented as an inhalation aerosol (metered‑dose inhaler) for inhalation use. They treat asthma and chronic obstructive pulmonary disease in adults and adolescents, providing anti‑inflammatory and bronchodilatory actions that help maintain airway patency and reduce exacerbations.

GNH USA supplies Kantos Master as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide, ensuring consistent quality and regulatory compliance across global markets.

What is Formoterol Fumarate Dihydrate, Beclometasone Dipropionate Anhydrous used for?

Kantos Master combines an inhaled corticosteroid with a long‑acting β2‑agonist to manage obstructive airway diseases.

Asthma: improves symptom control and reduces the frequency of exacerbations. COPD: enhances lung function and decreases dyspnea during daily activities. Chronic bronchitis (COPD component): reduces cough and sputum production, improving quality of life.

What are the side effects of Formoterol Fumarate Dihydrate, Beclometasone Dipropionate Anhydrous?

Common Side Effects: - Throat irritation or hoarseness. - Oral candidiasis (thrush). - Cough after inhalation. - Headache.

Serious or Rare Side Effects: - Paradoxical bronchospasm. - Adrenal suppression with prolonged high‑dose use. - Severe allergic reactions, including anaphylaxis. - Cardiac arrhythmias or tachycardia.

What precautions apply to Formoterol Fumarate Dihydrate, Beclometasone Dipropionate Anhydrous?

Kantos Master should be used under medical supervision with attention to the following precautions. - Assess asthma or COPD control before initiating therapy. - Monitor for oral thrush and advise rinsing the mouth after each inhalation. - Avoid abrupt discontinuation; taper if used at high doses for a long period. - Use with caution in patients with cardiovascular disease. - Use with caution during pregnancy and lactation (category unknown). - Store at ambient temperature: keep in the original pack, protect from moisture and heat.

What does Formoterol Fumarate Dihydrate, Beclometasone Dipropionate Anhydrous interact with?

Kantos Master may interact with other medicines; relevant interactions are grouped below. Major Interactions (Avoid): - Beta‑blockers: may diminish bronchodilator effect and precipitate bronchospasm. - Strong CYP3A4 inhibitors (e.g., ketoconazole): increase systemic corticosteroid exposure. Moderate Interactions (Monitor Closely): - Theophylline: may increase plasma concentrations; monitor levels. - Diuretics: monitor potassium as LABA can cause hypokalemia. - Ritonavir or other potent CYP3A4 inhibitors: may raise steroid levels, watch for systemic effects.

Frequently asked questions

What is Kantos Master used for?+
Kantos Master is a prescription inhaler that combines formoterol fumarate and beclometasone dipropionate. It is indicated for the maintenance treatment of asthma and chronic obstructive pulmonary disease (COPD) in adults and adolescents, helping to control symptoms, reduce inflammation, and prevent exacerbations when used regularly as part of a comprehensive management plan.
How does formoterol fumarate work?+
Formoterol fumarate is a long‑acting β2‑adrenergic agonist. It binds to β2 receptors on airway smooth‑muscle cells, activating adenylate cyclase and increasing cyclic AMP levels, which leads to relaxation of the bronchial smooth muscle and prolonged bronchodilation for up to 12 hours, improving airflow in obstructive airway diseases.
How does beclometasone dipropionate work?+
Beclometasone dipropionate is an inhaled corticosteroid that penetrates airway cells and binds to glucocorticoid receptors. This interaction modulates gene transcription, suppressing the production of inflammatory cytokines, reducing airway edema, mucus secretion, and hyper‑responsiveness, thereby providing anti‑inflammatory control of asthma and COPD.
What is the usual dose?+
The specific dose and inhalation schedule for Kantos Master are determined by the prescribing healthcare professional based on the severity of the disease, patient age, and response to therapy. Patients should follow the prescriber’s instructions and the device’s dosing counter, and never adjust the dose without medical advice.
Is Kantos Master safe in pregnancy or breastfeeding?+
The safety of Kantos Master in pregnancy and lactation has not been fully established, and the product carries an unknown pregnancy category. Clinicians should weigh the potential benefits against possible risks, and pregnant or nursing women should discuss treatment options with their healthcare provider before using this inhaler.
How do I order Kantos Master from GNH USA?+
To place an enquiry, visit the product page on gnh-usa.com, enter the required quantity, and submit the request. GNH USA works with hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including any cold‑chain requirements), and necessary import documentation.
How does Kantos Master compare with other combination inhalers?+
Kantos Master contains the same active ingredients—formoterol and beclometasone—as many other licensed combination inhalers, offering comparable efficacy in reducing symptoms and exacerbations. Differences may lie in device design, dose strength, and regional regulatory approvals; clinicians choose a product based on patient preference, inhaler technique, and local formularies.
What are the storage and handling requirements?+
Kantos Master should be stored at ambient temperature, below 25 °C, in its original packaging to protect it from moisture and heat. Keep the inhaler away from direct sunlight and do not expose it to freezing conditions. Ensure the mouthpiece remains clean and replace the canister according to the manufacturer’s expiration date.
How is the inhaler administered?+
The patient should remove the cap, shake the inhaler gently, and exhale fully away from the device. Press down on the canister to release a metered dose while beginning a slow, steady inhalation, then hold the breath for about 10 seconds before exhaling. Rinse the mouth after each use to reduce the risk of oral thrush.
Who should not use Kantos Master?+
Kantos Master is contraindicated in patients with a known hypersensitivity to formoterol, beclometasone, or any excipients in the inhaler. It should also be avoided in individuals who have experienced a severe paradoxical bronchospasm with LABA therapy. Patients with uncontrolled cardiovascular disease should use it only under close medical supervision.
Information provided on this page is for educational use by procurement and clinical professionals. Always consult a licensed healthcare provider for medical advice and prescribing decisions. GNH USA supplies this product subject to applicable regulatory and licensing requirements.

Product details

Drug
Formoterol Fumarate Dihydrate, Beclometasone Dipropionate Anhydrous
Route
Inhalation Use
Manufacturer
Chiesi Farmaceutici S.P.A.
Origin
EU

Related products