GNH USA

Europe — EMA

Kandrozid

GNH USA supplies Kandrozid (Candesartan Cilexetil), a angiotensin II receptor blocker for hypertension, heart failure and diabetic nephropathy.

Candesartan Cilexetil

Request sourcing

1
Pack/s

What is Candesartan Cilexetil?

Candesartan Cilexetil, the active ingredient in Kandrozid, is an angiotensin II receptor blocker (ARB) presented as an oral tablet for oral use. It is employed to manage high blood pressure, support heart failure treatment, and protect kidney function in diabetic patients.

GNH USA supplies Kandrozid as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

What is Candesartan Cilexetil used for?

Kandrozid, an angiotensin II receptor blocker, acts on the renin‑angiotensin system to control cardiovascular conditions. - Hypertension: lowers elevated blood pressure and reduces cardiovascular risk. - Heart failure: improves symptoms and decreases hospitalisation rates. - Diabetic nephropathy: slows progression of kidney damage associated with diabetes.

What are the side effects of Candesartan Cilexetil?

Adverse reactions may occur with any medication and should be monitored by a healthcare professional.

Common Side Effects: - Dizziness or light‑headedness. - Headache. - Fatigue. - Upper respiratory tract infection. - Cough. - Diarrhoea.

Serious or Rare Side Effects: - Hyperkalaemia. - Acute kidney injury. - Angio‑oedema. - Severe hypotension. - Liver enzyme elevations. - Myocardial infarction in rare cases.

What precautions apply to Candesartan Cilexetil?

Before initiating therapy, consider the following safety measures. - Pregnancy: Avoid use; classified as Category D due to fetal risk. - Renal impairment: Adjust therapy and monitor kidney function. - Hepatic impairment: Use with caution; monitor liver enzymes. - Concomitant potassium‑sparing agents: Watch for hyperkalaemia. - Volume depletion or diuretic therapy: Assess blood pressure frequently. - Store at ambient temperature: keep below 25 °C, protect from moisture and light in the original container.

What does Candesartan Cilexetil interact with?

Candesartan can interact with several drug classes, requiring attention to avoid adverse outcomes.

Major Interactions (Avoid): - Aliskiren (in patients with diabetes or renal impairment). - Potassium supplements or potassium‑sparing diuretics (risk of hyperkalaemia). - Dual renin‑angiotensin system blockade (e.g., ACE inhibitors, other ARBs).

Moderate Interactions (Monitor Closely): - Non‑steroidal anti‑inflammatory drugs (may reduce antihypertensive effect). - Lithium (increased lithium levels). - Cyclosporine (enhanced candesartan exposure).

Frequently asked questions

What conditions is Kandrozid used to treat?+
Kandrozid contains candesartan cilexetil and is prescribed for hypertension, chronic heart failure, and diabetic nephropathy. By lowering blood pressure and reducing strain on the heart and kidneys, it helps manage these cardiovascular and renal conditions under medical supervision.
How does candesartan cilexetil work in the body?+
Candesartan cilexetil is a prodrug that is converted to candesartan, which selectively blocks the angiotensin II type 1 (AT1) receptor. This inhibition prevents angiotensin II‑induced vasoconstriction and aldosterone release, resulting in vasodilation, reduced sodium retention, and lower systemic blood pressure.
What is the usual dose of Kandrozid?+
The appropriate dose of Kandrozid is determined by the prescribing clinician based on the patient’s medical condition, response to therapy, and renal function. Dosage adjustments are made individually; patients should follow the prescriber’s instructions and not alter the dose on their own.
Is Kandrozid safe to use during pregnancy or breastfeeding?+
Kandrozid is classified as Pregnancy Category D, indicating evidence of fetal risk. It should be avoided during pregnancy unless the potential benefit justifies the risk. Limited data are available for breastfeeding; therefore, use is generally not recommended without a thorough risk‑benefit assessment by a healthcare professional.
How do I order Kandrozid from GNH USA?+
To place an order, submit an enquiry on the product page at gnh-usa.com specifying the required quantity of Kandrozid. GNH USA works with hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details, and any necessary import documentation.
How does Kandrozid compare with other antihypertensive classes?+
Kandrozid belongs to the angiotensin II receptor blocker (ARB) class, which offers blood‑pressure control similar to ACE inhibitors but with a lower incidence of cough and angio‑edema. Compared with calcium‑channel blockers or diuretics, ARBs provide a distinct mechanism focused on the renin‑angiotensin system, often used when those alternatives are unsuitable.
What are the recommended storage conditions for Kandrozid?+
Kandrozid should be stored at ambient temperature, preferably below 25 °C, in its original packaging. Protect the tablets from moisture, excessive heat, and direct sunlight to maintain product stability throughout its shelf life.
How is Kandrozid administered to patients?+
Kandrozid is taken orally, usually once daily, with or without food as directed by the prescriber. Swallow the tablet whole with a glass of water; do not crush, split, or chew unless specifically instructed by a healthcare professional.
What are the most serious risks associated with Kandrozid?+
Serious risks, though uncommon, include hyperkalaemia, acute kidney injury, severe hypotension, and angio‑edema. Patients should be monitored for signs such as swelling of the face or throat, rapid weight gain, or a sudden drop in blood pressure, and seek immediate medical attention if these occur.
Who should not take Kandrozid?+
Kandrozid is contraindicated in patients with known hypersensitivity to candesartan or any component of the formulation, those with severe hepatic impairment, and individuals who are pregnant. It should also be avoided in patients taking aliskiren if they have diabetes or moderate to severe renal impairment.
Information provided on this page is for educational use by procurement and clinical professionals. Always consult a licensed healthcare provider for medical advice and prescribing decisions. GNH USA supplies this product subject to applicable regulatory and licensing requirements.
Send a sourcing enquiry for this product →

Product details

Drug
Candesartan Cilexetil
Route
Oral Use
Manufacturer
Viatris Limited
Origin
EU

Related products

A

A

Liquid Extract From Viscum Album Subsp. Abietis Var Abies Alba (1:20), Extraction Solvents: Water Fo

Helixor Heilmittel Gmbh
EU
A

A

Liquid Extract From Viscum Album Subsp. Abietis Var Abies Alba (1:20), Extraction Solvents: Water Fo

Helixor Heilmittel Gmbh
EU
A

A

Liquid Extract From Viscum Album Subsp. Abietis Var Abies Alba (1:20), Extraction Solvents: Water Fo

Helixor Heilmittel Gmbh
EU
A

A

Liquid Extract From Viscum Album Subsp. Abietis Var Abies Alba (1:20), Extraction Solvents: Water Fo

Helixor Heilmittel Gmbh
EU