GNH USA

Europe — EMA

Kanavig

GNH USA supplies Kanavig (Moxifloxacin), a fluoroquinolone antibiotic for bacterial conjunctivitis, keratitis and blepharitis. Request a quote for supply.

Moxifloxacin Hydrochloride

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What is Moxifloxacin Hydrochloride?

Moxifloxacin Hydrochloride, the active ingredient in Kanavig, is a fluoroquinolone antibiotic presented as a 0.5% w/v ophthalmic solution for ocular (topical eye drops) use. It treats bacterial eye infections such as bacterial conjunctivitis, bacterial keratitis and blepharitis in patients requiring antibiotic therapy.

GNH USA supplies Kanavig as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide, ensuring quality and regulatory compliance across markets.

What is Moxifloxacin Hydrochloride used for?

Kanavig (moxifloxacin hydrochloride) is a fluoroquinolone ophthalmic antibiotic used to treat bacterial infections of the eye.

- Bacterial conjunctivitis: reduces bacterial load, relieving redness, discharge and irritation. - Bacterial keratitis: eradicates causative bacteria, promoting corneal healing and preventing scarring. - Blepharitis: controls bacterial overgrowth on the eyelid margin, improving symptoms and reducing recurrence.

What are the side effects of Moxifloxacin Hydrochloride?

Kanavig may cause ocular adverse reactions, ranging from mild irritation to rare serious events.

Common Side Effects: - Stinging or burning: transient discomfort upon instillation. - Redness: mild conjunctival hyperemia. - Tearing: increased lacrimation. - Blurred vision: temporary visual disturbance.

Serious or Rare Side Effects: - Corneal ulceration: progressive corneal damage. - Anterior uveitis: inflammation of the anterior chamber. - Severe allergic reaction: swelling, itching, or rash around the eye.

What precautions apply to Moxifloxacin Hydrochloride?

Before using Kanavig, consider the following precautions to ensure safe and effective therapy.

- Indication confirmation: ensure a bacterial eye infection is diagnosed before treatment. - Contact lens use: remove lenses prior to instillation and wait before reinserting. - Systemic absorption: avoid excessive dosing; monitor for systemic fluoroquinolone effects. - Pregnancy and lactation: safety not established; use only if benefits outweigh potential risks. - Allergic history: assess for hypersensitivity to fluoroquinolones or any formulation component. - Store at room temperature: keep in the original container, protect from light and moisture.

What does Moxifloxacin Hydrochloride interact with?

Kanavig can interact with other medications; awareness of these interactions helps minimize risks.

Major Interactions (Avoid): - Systemic fluoroquinolones: concurrent systemic use may increase risk of tendon rupture. - Anticholinergic eye drops: may reduce the antibacterial efficacy of moxifloxacin. - Strong CYP450 inhibitors: may alter systemic exposure despite minimal ocular absorption.

Moderate Interactions (Monitor Closely): - Non‑steroidal anti‑inflammatory eye drops: may affect corneal healing. - Corticosteroid eye drops: monitor for delayed resolution of infection. - Other topical antibiotics: avoid overlapping therapy to reduce resistance development.

Frequently asked questions

What is Kanavig used for?+
Kanavig is an ophthalmic solution containing moxifloxacin hydrochloride. It is prescribed to treat bacterial eye infections such as bacterial conjunctivitis, bacterial keratitis, and blepharitis, helping to eliminate the causative organisms and relieve associated symptoms.
How does moxifloxacin hydrochloride work?+
Moxifloxacin hydrochloride blocks bacterial DNA gyrase and topoisomerase IV, enzymes required for DNA replication and transcription. By preventing these processes, the drug exerts a bactericidal effect against a wide range of Gram‑positive and Gram‑negative ocular pathogens.
What is the usual dose of Kanavig?+
The dosing regimen for Kanavig is determined by the prescribing clinician based on the specific infection, severity, and patient factors. The prescriber will specify the number of drops, frequency, and duration appropriate for each case.
Is Kanavig safe during pregnancy or breastfeeding?+
Safety data for moxifloxacin ophthalmic use in pregnancy and lactation are limited. The product should be used only if the potential benefit justifies any potential risk to the fetus or infant, and this decision must be made by the treating physician.
How do I order Kanavig from GNH USA?+
To order Kanavig, submit an enquiry on the product page at gnh-usa.com, indicating the required quantity. GNH USA works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.
How does Kanavig compare with the main alternative drug or class?+
Kanavig belongs to the fluoroquinolone class, similar to ciprofloxacin eye drops. Compared with older fluoroquinolones, moxifloxacin offers a broader spectrum against Gram‑positive organisms and often requires a shorter treatment course, though choice depends on local resistance patterns and physician preference.
How should Kanavig be stored and handled?+
Kanavig should be stored at room temperature, below 25 °C, in its original container. Protect the bottle from direct sunlight and moisture. Do not freeze the solution, and keep the cap tightly closed when not in use.
How is Kanavig administered?+
Kanavig is applied as eye drops. The patient should wash hands, tilt the head back, pull down the lower eyelid to form a pocket, and instill the prescribed number of drops. The eye should be closed gently for a few seconds to allow absorption, and contact lenses should be removed before use.
What are the most serious risks to watch for while using Kanavig?+
Serious ocular risks include corneal ulceration, anterior uveitis, and severe allergic reactions such as swelling or rash around the eye. If any of these occur, the patient should discontinue the drops and seek immediate medical attention.
Who should not use Kanavig?+
Kanavig should not be used by individuals with a known hypersensitivity to moxifloxacin, other fluoroquinolones, or any component of the formulation. It is also contraindicated in patients with active viral or fungal eye infections where an antibacterial agent would be inappropriate.
Information provided on this page is for educational use by procurement and clinical professionals. Always consult a licensed healthcare provider for medical advice and prescribing decisions. GNH USA supplies this product subject to applicable regulatory and licensing requirements.

Product details

Drug
Moxifloxacin Hydrochloride
Route
Ocular Use
Manufacturer
Novartis Pharma N.V.
Origin
EU

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