GNH USA

Europe — EMA

Kalms Night One-A-Night

GNH USA supplies Kalms Night One-A-Night (Valerian root extract), a herbal sedative for sleep disturbances and insomnia. Request a quote for global supply.

Dry Extract Of Valerian Root, Extraction Solvent: Ethanol 60% V/V

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What is Dry Extract Of Valerian Root, Extraction Solvent: Ethanol 60% V/V?

Valerian root extract, the active ingredient in Kalms Night One-A-Night, is a herbal sedative presented as a dry extract for oral use. It is intended to help adults who experience occasional sleep disturbances or difficulty falling asleep. GNH USA supplies Kalms Night One-A-Night as a licensed, GDP‑compliant international pharmaceutical supplier serving pharmacies and clinics worldwide.

What is Dry Extract Of Valerian Root, Extraction Solvent: Ethanol 60% V/V used for?

Kalms Night One-A-Night is an herbal sleep aid that acts on the central nervous system to promote relaxation and improve sleep quality. - Sleep disturbances: helps reduce the time needed to fall asleep and supports a more restful night. - Insomnia: may improve overall sleep duration and continuity in individuals with occasional insomnia. - Difficulty maintaining sleep: can aid in reducing nighttime awakenings and promote longer sleep periods.

What are the side effects of Dry Extract Of Valerian Root, Extraction Solvent: Ethanol 60% V/V?

Kalms Night One-A-Night is generally well tolerated, but some users may experience adverse reactions.

Common Side Effects: - Headache: mild to moderate discomfort. - Dizziness: transient sensation of light‑headedness. - Gastrointestinal upset: nausea, stomach discomfort or mild diarrhoea. - Dry mouth: reduced salivation. - Fatigue: feeling of tiredness during the day. - Vivid dreams: unusually intense or memorable dreams.

Serious or Rare Side Effects: - Allergic reaction: rash, itching, swelling, or difficulty breathing. - Liver enzyme elevation: abnormal liver function tests in rare cases. - Severe hypotension: unusually low blood pressure causing faintness. - Anaphylaxis: rapid, life‑threatening allergic response. - Skin reactions: Stevens‑Johnson syndrome or toxic epidermal necrolysis. - Psychiatric changes: rare reports of increased anxiety or depression.

What precautions apply to Dry Extract Of Valerian Root, Extraction Solvent: Ethanol 60% V/V?

When considering Kalms Night One-A-Night, several safety measures should be observed. - Pregnancy: safety not established; avoid use unless advised by a healthcare professional. - Breastfeeding: caution advised as the extract may pass into milk. - Concurrent CNS depressants: monitor for enhanced sedation when combined with alcohol, benzodiazepines, or antihistamines. - Elderly patients: increased risk of falls; start with the lowest effective dose. - Liver disease: use with caution in patients with known hepatic impairment. - Store at ambient temperature: keep in the original packaging, protect from moisture and direct sunlight.

What does Dry Extract Of Valerian Root, Extraction Solvent: Ethanol 60% V/V interact with?

Kalms Night One-A-Night may interact with other medicines that affect the central nervous system.

Major Interactions (Avoid): - CNS depressants (e.g., benzodiazepines, barbiturates, alcohol): risk of excessive sedation or respiratory depression. - Opioids: may potentiate sedative effects and impair psychomotor function.

Moderate Interactions (Monitor Closely): - Antidepressants (SSRIs, SNRIs): possible additive effects on sleep architecture. - Antihistamines: increased drowsiness. - Anticonvulsants (e.g., phenobarbital): potential alteration of seizure threshold. - Anticoagulants: theoretical risk of enhanced bleeding, though evidence is limited.

Frequently asked questions

What is Kalms Night One-A-Night used for?+
Kalms Night One-A-Night is an over‑the‑counter herbal product containing valerian root extract. It is used to help adults who have occasional difficulty falling asleep, experience brief periods of insomnia, or suffer from mild sleep disturbances. The formulation is intended to promote relaxation and support a more natural sleep onset without prescription medication.
How does valerian root extract work to improve sleep?+
Valerian root extract contains valerenic acids and other phytochemicals that are believed to influence the GABAergic system in the brain. By enhancing GABA activity, reducing neuronal excitability, and interacting with adenosine receptors, the extract produces a mild calming effect that can shorten the time needed to fall asleep and improve overall sleep quality.
What is the usual dose of Kalms Night One-A-Night?+
The appropriate dose of Kalms Night One-A-Night is determined by the prescribing healthcare professional based on individual needs, age, and health status. Patients should follow the specific instructions provided by their doctor or pharmacist and not exceed the recommended amount without medical guidance.
Is Kalms Night One-A-Night safe during pregnancy or breastfeeding?+
Safety data for valerian root extract in pregnancy and lactation are limited. It is generally advised that pregnant or breastfeeding women avoid using Kalms Night One-A-Night unless a qualified healthcare provider determines that the potential benefits outweigh any possible risks.
How do I order Kalms Night One-A-Night from GNH USA?+
To place an order, submit an enquiry on the product page at gnh-usa.com, specifying the required quantity. GNH USA works with hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including any cold‑chain requirements), and assistance with import documentation.
How does Kalms Night One-A-Night compare with other sleep aids?+
Compared with synthetic hypnotics, Kalms Night One-A-Night offers a herbal alternative that may have a milder side‑effect profile and lower risk of dependence. However, its onset of action can be slower, and efficacy may vary between individuals. It is generally considered for mild to moderate sleep issues, whereas prescription agents are reserved for more severe insomnia.
What are the storage and handling requirements for Kalms Night One-A-Night?+
Store Kalms Night One-A-Night at ambient temperature, preferably below 25 °C. Keep the product in its original packaging, protect it from moisture, direct sunlight, and extreme heat. Ensure the container is tightly closed to maintain product stability.
How is Kalms Night One-A-Night administered?+
Kalms Night One-A-Night is taken orally, typically with a glass of water shortly before bedtime. The exact timing and amount should follow the prescriber's instructions. Swallow the tablet or capsule whole; do not crush or chew unless specifically directed.
What are the most serious risks associated with Kalms Night One-A-Night?+
Serious risks, though rare, include severe allergic reactions such as anaphylaxis, significant liver enzyme elevations, and marked hypotension leading to fainting. Users should seek immediate medical attention if they experience difficulty breathing, swelling of the face or throat, intense rash, or sudden drops in blood pressure.
Who should not use Kalms Night One-A-Night?+
Individuals with known hypersensitivity to valerian or any component of the formulation should avoid the product. It is also contraindicated for patients taking strong CNS depressants, those with severe liver disease, pregnant or breastfeeding women without medical advice, and anyone who has experienced serious adverse reactions to herbal sedatives.
Information provided on this page is for educational use by procurement and clinical professionals. Always consult a licensed healthcare provider for medical advice and prescribing decisions. GNH USA supplies this product subject to applicable regulatory and licensing requirements.

Product details

Drug
Dry Extract Of Valerian Root, Extraction Solvent: Ethanol 60% V/V
Route
Oral Use
Manufacturer
G R Lane Health Products Ltd.
Origin
EU

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