GNH USA

Europe — EMA

Kalcizen

GNH USA supplies Kalcizen (Colecalciferol, Calcium Carbonate), a vitamin D and calcium supplement for bone health and calcium deficiency.

Colecalciferol, Calcium Carbonate

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What is Colecalciferol, Calcium Carbonate?

Colecalciferol, the active ingredient in Kalcizen, is a vitamin D supplement presented as an oral tablet for oral use. It provides vitamin D3 together with calcium carbonate to support calcium absorption and bone health in adults and children with deficiency.

GNH USA supplies Kalcizen as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

What is Colecalciferol, Calcium Carbonate used for?

Kalcizen is a combined vitamin D3 and calcium supplement that addresses calcium‑related metabolic pathways and bone health. - Osteoporosis: supports bone mineral density and helps reduce fracture risk. - Hypocalcemia: supplies calcium to correct low serum calcium levels. - Vitamin D deficiency: raises serum 25‑hydroxyvitamin D concentrations. - Post‑menopausal bone health: aids calcium absorption to maintain skeletal strength.

What are the side effects of Colecalciferol, Calcium Carbonate?

Kalcizen may cause adverse reactions, most of which are mild and reversible.

Common Side Effects: - Nausea: mild stomach upset after ingestion. - Constipation: reduced bowel movements. - Flatulence: increased intestinal gas. - Hypercalcemia (mild): elevated serum calcium without symptoms. - Headache: occasional mild headache.

Serious or Rare Side Effects: - Severe hypercalcemia: may cause confusion, cardiac arrhythmia, or renal impairment. - Kidney stones: calcium precipitation in the urinary tract. - Allergic reaction: rash, itching, or swelling. - Hypervitaminosis D: excessive vitamin D leading to toxicity.

What precautions apply to Colecalciferol, Calcium Carbonate?

Before initiating Kalcizen, consider the following precautions. - Assess calcium status: evaluate serum calcium levels to avoid excess. - Monitor vitamin D levels: check 25‑hydroxyvitamin D to guide supplementation. - Renal impairment: use with caution in patients with reduced kidney function. - Hypercalcemia: avoid in individuals with known high calcium levels. - Drug interactions: review concomitant medications that affect calcium balance. - Store below 25°C: keep in the original packaging, protect from moisture and direct sunlight.

What does Colecalciferol, Calcium Carbonate interact with?

Kalcizen can interact with other medicines that influence calcium or vitamin D metabolism.

Major Interactions (Avoid): - Thiazide diuretics: may increase risk of hypercalcemia. - Excess vitamin A: combined high intake can precipitate hypervitaminosis D.

Moderate Interactions (Monitor Closely): - Bisphosphonates: calcium may reduce their gastrointestinal absorption. - Corticosteroids: may increase vitamin D requirements. - Anticonvulsants (e.g., phenytoin): can lower vitamin D levels, reducing efficacy.

Frequently asked questions

What is Kalcizen used for?+
Kalcizen is a combined vitamin D3 (colecalciferol) and calcium carbonate oral supplement used to support calcium absorption, maintain bone health, prevent osteoporosis, and treat calcium or vitamin D deficiency in adults and children.
How does colecalciferol work?+
Colecalciferol (vitamin D3) is converted in the liver to 25‑hydroxyvitamin D and then in the kidney to the active hormone calcitriol, which binds to vitamin D receptors in the intestinal lining, increasing the expression of calcium‑transport proteins and thereby enhancing dietary calcium absorption.
What is the usual dose of Kalcizen?+
The appropriate dose of Kalcizen is determined by the prescribing healthcare professional based on the individual’s age, serum calcium and vitamin D levels, and clinical needs. Patients should follow the prescriber’s instructions and not adjust the dose on their own.
Is Kalcizen safe during pregnancy or breastfeeding?+
Kalcizen may be used during pregnancy or lactation when prescribed, as vitamin D and calcium are essential nutrients. However, the prescriber should evaluate the mother’s nutritional status and any potential risks before recommending supplementation.
How do I order Kalcizen from GNH USA?+
To order Kalcizen, submit an enquiry on the product page at gnh-usa.com with the required quantity. GNH USA supplies hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and necessary import documentation.
How does Kalcizen compare with other calcium‑vitamin D products?+
Kalcizen combines colecalciferol and calcium carbonate in a single oral formulation, offering both vitamin D3 and elemental calcium. Compared with products that contain only calcium or only vitamin D, Kalcizen provides a synergistic effect on calcium absorption, which can be more convenient for patients needing both nutrients.
What are the storage and handling requirements for Kalcizen?+
Store Kalcizen below 25 °C in its original packaging, protecting it from moisture and direct sunlight. Keep the container tightly closed and out of reach of children. No special refrigeration is required for this oral tablet.
How is Kalcizen administered?+
Kalcizen is taken orally, usually with a glass of water. It can be taken with or without food, but some patients find it easier to swallow with meals to reduce gastrointestinal discomfort.
What are the most serious risks associated with Kalcizen?+
The most serious risks include severe hypercalcemia, which can cause confusion, cardiac arrhythmias, or kidney damage, and the formation of kidney stones. Rare allergic reactions such as rash, swelling, or anaphylaxis may also occur and require immediate medical attention.
Who should not use Kalcizen?+
Kalcizen should be avoided in individuals with known hypercalcemia, severe renal impairment, or a documented hypersensitivity to colecalciferol, calcium carbonate, or any excipients in the tablet. Patients with certain metabolic disorders should consult their physician before use.
Information provided on this page is for educational use by procurement and clinical professionals. Always consult a licensed healthcare provider for medical advice and prescribing decisions. GNH USA supplies this product subject to applicable regulatory and licensing requirements.

Product details

Drug
Colecalciferol, Calcium Carbonate
Route
Oral Use
Manufacturer
Zentiva, K.S.
Origin
EU

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