Kalcizen (Colecalciferol, Calcium Carbonate)

Colecalciferol, the active ingredient in Kalcizen, is a vitamin D supplement presented as an oral tablet for oral use. It provides vitamin D3 together with calcium carbonate to support calcium absorption and bone health in adults and children with deficiency.

GNH USA supplies Kalcizen as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Kalcizen is a combined vitamin D3 and calcium supplement that addresses calcium‑related metabolic pathways and bone health. - Osteoporosis: supports bone mineral density and helps reduce fracture risk. - Hypocalcemia: supplies calcium to correct low serum calcium levels. - Vitamin D deficiency: raises serum 25‑hydroxyvitamin D concentrations. - Post‑menopausal bone health: aids calcium absorption to maintain skeletal strength.

Kalcizen may cause adverse reactions, most of which are mild and reversible.

Common Side Effects: - Nausea: mild stomach upset after ingestion. - Constipation: reduced bowel movements. - Flatulence: increased intestinal gas. - Hypercalcemia (mild): elevated serum calcium without symptoms. - Headache: occasional mild headache.

Serious or Rare Side Effects: - Severe hypercalcemia: may cause confusion, cardiac arrhythmia, or renal impairment. - Kidney stones: calcium precipitation in the urinary tract. - Allergic reaction: rash, itching, or swelling. - Hypervitaminosis D: excessive vitamin D leading to toxicity.

Before initiating Kalcizen, consider the following precautions. - Assess calcium status: evaluate serum calcium levels to avoid excess. - Monitor vitamin D levels: check 25‑hydroxyvitamin D to guide supplementation. - Renal impairment: use with caution in patients with reduced kidney function. - Hypercalcemia: avoid in individuals with known high calcium levels. - Drug interactions: review concomitant medications that affect calcium balance. - Store below 25°C: keep in the original packaging, protect from moisture and direct sunlight.

Kalcizen can interact with other medicines that influence calcium or vitamin D metabolism.

Major Interactions (Avoid): - Thiazide diuretics: may increase risk of hypercalcemia. - Excess vitamin A: combined high intake can precipitate hypervitaminosis D.

Moderate Interactions (Monitor Closely): - Bisphosphonates: calcium may reduce their gastrointestinal absorption. - Corticosteroids: may increase vitamin D requirements. - Anticonvulsants (e.g., phenytoin): can lower vitamin D levels, reducing efficacy.