Kalcium/Kolekalciferol Evolan

Colecalciferol, the active ingredient in Kalcium/Kolekalciferol Evolan, is a vitamin D3 and calcium supplement presented as a nutritional supplement for oral use. It addresses calcium and vitamin D deficiencies and supports bone health in both adults and children.

GNH USA supplies Kalcium/Kolekalciferol Evolan as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide. The company adheres to stringent quality standards and provides reliable logistics for global distribution. With a focus on regulatory compliance, GNH USA ensures product integrity throughout the supply chain.

Kalcium/Kolekalciferol Evolan is used to correct deficiencies in calcium and vitamin D, supporting skeletal health.

- Calcium deficiency: helps restore normal calcium levels and promotes bone mineralization. - Vitamin D deficiency: provides vitamin D3 to enhance intestinal calcium absorption. - Bone health support: contributes to maintaining bone density in individuals at risk of osteopenia or osteoporosis.

Kalcium/Kolekalciferol Evolan may be associated with several adverse reactions, which are categorized by frequency and severity.

Common Side Effects: - Hypercalcemia: elevated blood calcium causing fatigue, nausea, or mild weakness. - Gastrointestinal discomfort: abdominal pain, constipation, flatulence, or mild indigestion. - Headache: transient mild headache. - Metallic taste: occasional taste disturbance in the mouth. - Mild dizziness: occasional light‑headedness.

Serious or Rare Side Effects: - Hypercalciuria: excessive urinary calcium excretion that can lead to kidney stone formation. - Severe allergic reaction: rash, itching, swelling, or anaphylaxis. - Hypervitaminosis D: toxicity from excess vitamin D resulting in soft‑tissue calcification. - Cardiac arrhythmia: rare but reported in cases of severe hypercalcemia. - Acute pancreatitis: very rare inflammatory response of the pancreas.

When using Kalcium/Kolekalciferol Evolan, certain precautions should be observed to ensure safety.

- Assess baseline calcium and vitamin D levels: avoid supplementation if normal. - Monitor renal function: patients with kidney disease may accumulate calcium. - Review concomitant medications: especially thiazide diuretics or digitalis. - Limit use in hyperparathyroidism: risk of exacerbating hypercalcemia. - Avoid in known hypersensitivity to calcium carbonate or vitamin D3: discontinue if reaction occurs. - Store at ambient temperature: keep in original container, protect from moisture and direct sunlight.

Kalcium/Kolekalciferol Evolan can interact with other medicines, requiring attention to avoid adverse outcomes.

Major Interactions (Avoid): - Thiazide diuretics: may increase risk of hypercalcemia. - Calcium channel blockers: can potentiate calcium‑related cardiac effects. - High‑dose vitamin A: synergistic hypercalcemia risk.

Moderate Interactions (Monitor Closely): - Bisphosphonates: concurrent use may affect calcium balance. - Anticonvulsants (e.g., phenobarbital, phenytoin): may reduce vitamin D effectiveness. - Corticosteroids: can impair calcium absorption, requiring dose adjustment.