GNH USA

Europe — EMA

Kabiven

GNH USA supplies Kabiven (Amino Acid Solution), a parenteral nutrition product for patients unable to receive enteral feeding. Request a quote for supply.

Valine, Alanine, Arginine, Histidine, Isoleucine, Leucine, Methionine, Phenylalanine, Proline, Serin

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What is Valine, Alanine, Arginine, Histidine, Isoleucine, Leucine, Methionine, Phenylalanine, Proline, Serin?

Valine, Alanine, Arginine, Histidine, Isoleucine, Leucine, Methionine, Phenylalanine, Proline, Serine, the active ingredients in Kabiven, are an amino acid solution presented as a parenteral nutrition solution for intravenous use. It supports protein synthesis and nitrogen balance in patients who cannot receive oral or enteral feeding.

GNH USA supplies Kabiven as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, transplant centres and intensive care units worldwide.

What is Valine, Alanine, Arginine, Histidine, Isoleucine, Leucine, Methionine, Phenylalanine, Proline, Serin used for?

Kabiven is an amino acid solution used in parenteral nutrition to meet protein and nitrogen needs. - Enteral feeding intolerance: provides essential amino acids when oral or enteral intake is insufficient. - Surgical or trauma patients: helps maintain nitrogen balance during catabolic stress. - Critically ill patients: supports protein synthesis and metabolic needs in intensive care settings.

What are the side effects of Valine, Alanine, Arginine, Histidine, Isoleucine, Leucine, Methionine, Phenylalanine, Proline, Serin?

Kabiven may be associated with several adverse reactions during infusion.

Common Side Effects: - Hyperglycemia: elevated blood glucose levels, especially in diabetic patients. - Electrolyte imbalance: changes in serum potassium, sodium, or calcium. - Infusion site reactions: erythema, pain, or phlebitis at the catheter site. - Nausea or vomiting: gastrointestinal discomfort during administration.

Serious or Rare Side Effects: - Anaphylaxis: severe allergic reaction requiring immediate medical intervention. - Severe hypernatremia: markedly high serum sodium levels. - Hepatic dysfunction: abnormal liver enzyme elevations. - Thrombophlebitis: clot formation with inflammation in the vein.

What precautions apply to Valine, Alanine, Arginine, Histidine, Isoleucine, Leucine, Methionine, Phenylalanine, Proline, Serin?

When using Kabiven, clinicians should consider several safety measures. - Renal impairment: monitor nitrogen load and adjust infusion rate. - Liver disease: assess amino acid metabolism and liver function tests. - Electrolyte disturbances: check serum electrolytes regularly during therapy. - Hyperglycemia risk: monitor blood glucose in patients with diabetes. - Compatibility: avoid mixing with solutions that may precipitate amino acids. - Store at 2-8°C: keep refrigerated, protect from light, do not freeze or shake.

What does Valine, Alanine, Arginine, Histidine, Isoleucine, Leucine, Methionine, Phenylalanine, Proline, Serin interact with?

Kabiven can interact with other agents administered concurrently.

Major Interactions (Avoid): - Concurrent high‑dose amino acid solutions: risk of nitrogen overload. - Calcium‑containing solutions: potential precipitation of insoluble salts. - Certain antibiotics (e.g., aminoglycosides): mixing may reduce antibiotic efficacy.

Moderate Interactions (Monitor Closely): - Insulin therapy: may require dose adjustment due to glucose fluctuations. - Diuretics: monitor for electrolyte shifts during combined use. - Warfarin: observe INR as protein changes may affect drug binding.

Frequently asked questions

What is Kabiven used for?+
Kabiven is an amino acid solution formulated for parenteral nutrition. It is administered intravenously to patients who cannot receive adequate nutrition through oral or enteral routes, helping to meet their protein and nitrogen requirements during surgery, trauma, critical illness, or other conditions that limit normal feeding.
How does the amino acid mixture in Kabiven work?+
The mixture supplies both essential and non‑essential amino acids directly into the bloodstream. These amino acids serve as building blocks for protein synthesis, replenish nitrogen stores, and support metabolic pathways that are compromised when normal digestion and absorption are unavailable, thereby aiding tissue repair and maintaining cellular function.
What is the usual dose of Kabiven?+
The dose of Kabiven is individualized. A qualified prescriber determines the volume and rate of infusion based on the patient’s weight, clinical condition, metabolic needs, and laboratory parameters. No fixed regimen is provided; dosing is adjusted to achieve the desired nutritional goals while monitoring safety.
Is Kabiven safe to use during pregnancy or breastfeeding?+
Safety data for Kabiven in pregnancy and lactation are limited. The product should only be used if the potential benefit to the mother outweighs any possible risk to the fetus or infant. Clinicians must evaluate each case carefully and follow local regulatory guidance.
How do I order Kabiven from GNH USA?+
To order Kabiven, submit an enquiry on the product page at gnh-usa.com, specifying the required quantity. GNH USA works with hospitals, pharmacies, and procurement teams worldwide, confirming trade or institutional credentials before providing pricing, availability, shipping details (including cold‑chain handling if needed), and import documentation.
How does Kabiven compare with other parenteral nutrition amino acid solutions?+
Kabiven offers a comprehensive profile of essential and non‑essential amino acids in a single formulation, matching the amino acid composition recommended for adult parenteral nutrition. Compared with some older solutions that may lack certain essential amino acids, Kabiven provides a balanced mixture designed to reduce the risk of deficiencies and support optimal protein synthesis.
What are the storage and handling requirements for Kabiven?+
Kabiven must be stored at 2‑8 °C in a refrigerator. Keep the container in its original packaging, protect it from light, and avoid freezing or shaking the solution. Before use, inspect the product for any particulate matter or discoloration and discard if the integrity is compromised.
How is Kabiven administered?+
Kabiven is administered intravenously as a sterile solution for injection. It is typically infused through a central or peripheral venous catheter, either as a continuous infusion or in divided doses, according to the prescriber’s order and the patient’s clinical status. Infusion sets should be compatible and free of air bubbles.
What are the most serious risks associated with Kabiven?+
Serious risks include anaphylactic reactions, severe electrolyte disturbances such as hypernatremia, hepatic dysfunction, and thrombophlebitis at the infusion site. Prompt recognition and management of these events are essential. Clinicians should monitor vital signs, laboratory parameters, and infusion site condition throughout therapy.
Who should not receive Kabiven?+
Kabiven is contraindicated in patients with known hypersensitivity to any of its amino acid components. Caution is advised for individuals with severe renal or hepatic impairment, uncontrolled electrolyte abnormalities, or those receiving incompatible intravenous solutions. Clinical judgment should guide use in each specific situation.
Information provided on this page is for educational use by procurement and clinical professionals. Always consult a licensed healthcare provider for medical advice and prescribing decisions. GNH USA supplies this product subject to applicable regulatory and licensing requirements.
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Product details

Drug
Valine, Alanine, Arginine, Histidine, Isoleucine, Leucine, Methionine, Phenylalanine, Proline, Serin
Route
Intravenous Use
Manufacturer
Fresenius Kabi Ab
Origin
EU