GNH USA

Europe — EMA

Kabiven

GNH USA supplies Kabiven (Valine, Alanine, Arginine, Histidine, Isoleucine, Leucine, Methionine, Phenylalanine, Proline, Serin), a amino acid solution

Valine, Alanine, Arginine, Histidine, Isoleucine, Leucine, Methionine, Phenylalanine, Proline, Serin

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What is Valine, Alanine, Arginine, Histidine, Isoleucine, Leucine, Methionine, Phenylalanine, Proline, Serin?

Valine, Alanine, Arginine, Histidine, Isoleucine, Leucine, Methionine, Phenylalanine, Proline, Serin, the active ingredients in Kabiven, is an amino acid solution presented as a sterile solution for intravenous use. It provides essential and non‑essential amino acids to support protein synthesis and nitrogen balance in patients receiving parenteral nutrition.

GNH USA supplies Kabiven as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals worldwide.

What is Valine, Alanine, Arginine, Histidine, Isoleucine, Leucine, Methionine, Phenylalanine, Proline, Serin used for?

Kabiven is an amino acid solution used in parenteral nutrition to support protein synthesis and nitrogen balance. - Parenteral nutrition for patients who cannot receive enteral feeding: supplies a complete amino acid profile to meet nutritional needs. - Critically ill patients: supports protein synthesis and helps prevent catabolic loss. - Postoperative patients: provides essential amino acids to aid recovery and wound healing.

What are the side effects of Valine, Alanine, Arginine, Histidine, Isoleucine, Leucine, Methionine, Phenylalanine, Proline, Serin?

Kabiven may be associated with infusion‑related and metabolic adverse reactions.

Common Side Effects: - Hyperglycemia: elevated blood glucose during infusion. - Electrolyte imbalance: changes in serum potassium, sodium or calcium. - Phlebitis: irritation of the vein at the infusion site. - Mild fever or chills during administration.

Serious or Rare Side Effects: - Anaphylactic reaction: severe allergic response requiring immediate medical attention. - Metabolic acidosis: accumulation of acid metabolites. - Renal dysfunction: impaired kidney function in susceptible patients.

What precautions apply to Valine, Alanine, Arginine, Histidine, Isoleucine, Leucine, Methionine, Phenylalanine, Proline, Serin?

When using Kabiven, clinicians should consider several safety measures. - Renal impairment: monitor serum creatinine and adjust infusion volume. - Hepatic dysfunction: observe liver enzyme levels during therapy. - Electrolyte disturbances: check serum electrolytes before and during infusion. - Hyperglycemia risk: monitor blood glucose, especially in diabetic patients. - Compatibility: avoid mixing with calcium‑containing solutions that may precipitate. - Store at 2-8°C: keep refrigerated, protect from light, do not freeze or shake.

What does Valine, Alanine, Arginine, Histidine, Isoleucine, Leucine, Methionine, Phenylalanine, Proline, Serin interact with?

Kabiven can interact with other intravenous therapies and systemic medications.

Major Interactions (Avoid): - Concurrent high‑dose amino acid solutions: risk of nitrogen overload. - Incompatible IV solutions (e.g., calcium‑containing fluids): may cause precipitation.

Moderate Interactions (Monitor Closely): - Insulin therapy: may require dose adjustment due to glucose changes. - Diuretics: monitor electrolytes for shifts. - Renal replacement therapy: adjust amino acid provision based on clearance.

Frequently asked questions

What is Kabiven used for?+
Kabiven is an intravenous amino acid solution indicated for parenteral nutrition. It is used when patients cannot receive enteral feeding, such as in critical illness, postoperative recovery, or severe gastrointestinal dysfunction, to provide the essential building blocks for protein synthesis and maintain nitrogen balance.
How does the amino acid mixture in Kabiven work?+
The mixture supplies both essential and non‑essential amino acids directly into the bloodstream. Cells absorb these amino acids and incorporate them into new proteins, supporting tissue repair, immune function, and metabolic processes while helping to prevent catabolism in patients who are unable to ingest nutrients orally or enterally.
What is the usual dose of Kabiven?+
The dose of Kabiven is individualized. The prescribing clinician calculates the required volume and rate based on the patient’s weight, nutritional needs, renal and hepatic function, and overall clinical status. No fixed regimen is provided; dosing is determined by the healthcare professional.
Is Kabiven safe to use during pregnancy or breastfeeding?+
Safety data for Kabiven in pregnancy and lactation are limited. It should only be used when the potential benefit to the mother outweighs any possible risk to the fetus or infant, and the decision must be made by the treating physician.
How do I order Kabiven from GNH USA?+
To order Kabiven, submit an enquiry on the product page at gnh-usa.com, specifying the required quantity. GNH USA works with hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including cold‑chain if needed), and import documentation.
How does Kabiven compare with other amino acid solutions?+
Kabiven contains a comprehensive profile of ten amino acids, matching the composition of many standard parenteral amino acid formulations. Compared with some alternatives, it offers a balanced ratio of essential to non‑essential amino acids and is manufactured to EU standards, but clinicians should review specific product labels for differences in concentration and compatibility.
What are the storage and handling requirements for Kabiven?+
Kabiven must be stored refrigerated at 2‑8 °C. Keep the vial in its original packaging, protect it from light, and avoid freezing or shaking. If the solution reaches room temperature, it should be used promptly and not be returned to refrigeration.
How is Kabiven administered?+
Kabiven is administered intravenously using aseptic technique. The prescribed volume is diluted in an appropriate carrier fluid and infused over a period determined by the clinician, usually ranging from several hours to a full day, depending on the patient’s nutritional requirements and tolerance.
What are the most serious risks associated with Kabiven?+
Serious risks include anaphylactic reactions, metabolic acidosis, and renal dysfunction, especially in patients with pre‑existing kidney disease. Prompt recognition of symptoms such as difficulty breathing, severe hypotension, rapid pH changes, or worsening renal parameters is essential for immediate medical intervention.
Who should not use Kabiven?+
Kabiven should be avoided in patients with known hypersensitivity to any of its amino acid components, in those with severe renal failure where nitrogen load cannot be cleared, and in individuals with uncontrolled metabolic disorders that could be aggravated by amino acid infusion.
Information provided on this page is for educational use by procurement and clinical professionals. Always consult a licensed healthcare provider for medical advice and prescribing decisions. GNH USA supplies this product subject to applicable regulatory and licensing requirements.
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Product details

Drug
Valine, Alanine, Arginine, Histidine, Isoleucine, Leucine, Methionine, Phenylalanine, Proline, Serin
Route
Intravenous Use
Manufacturer
Fresenius Kabi Deutschland Gmbh
Origin
EU