GNH USA

Europe — EMA

Kabiven

GNH USA supplies Kabiven (Amino acids), a amino acid solution for parenteral nutrition in patients unable to receive enteral feeding.

Valine, Alanine, Arginine, Histidine, Isoleucine, Leucine, Methionine, Phenylalanine, Proline, Serin

Request sourcing

1
Pack/s

What is Valine, Alanine, Arginine, Histidine, Isoleucine, Leucine, Methionine, Phenylalanine, Proline, Serin?

Amino acid solution, the active ingredient in Kabiven, is a amino acid solution presented as a sterile solution for injection for intravenous use. It supplies essential amino acids required for protein synthesis and nitrogen balance, supporting the nutritional needs of patients who cannot receive enteral feeding, such as those in postoperative, trauma, or critical care settings.

GNH USA supplies Kabiven as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, transplant centres, oncology centres, pharmacies and clinics worldwide, with consistent quality and regulatory compliance.

What is Valine, Alanine, Arginine, Histidine, Isoleucine, Leucine, Methionine, Phenylalanine, Proline, Serin used for?

Kabiven is an amino acid solution used in parenteral nutrition to meet protein and nitrogen requirements when oral or tube feeding is not feasible. - Enteral feeding intolerance: provides necessary amino acids when oral or tube feeding is not possible. - Post‑operative recovery: helps meet protein requirements after surgery. - Critical illness or trauma: maintains nitrogen balance in severely ill patients.

What are the side effects of Valine, Alanine, Arginine, Histidine, Isoleucine, Leucine, Methionine, Phenylalanine, Proline, Serin?

Adverse reactions may occur with intravenous amino acid solutions.

Common Side Effects: - Hyperglycemia: elevated blood glucose levels. - Electrolyte imbalance: disturbances in serum potassium, sodium or calcium. - Fluid overload: excess volume leading to edema. - Local irritation: redness or pain at the infusion site. - Mild nausea: transient gastrointestinal discomfort.

Serious or Rare Side Effects: - Anaphylactic reaction: severe allergic response requiring immediate intervention. - Metabolic acidosis: significant drop in blood pH. - Severe hypernatremia: dangerously high sodium concentration.

What precautions apply to Valine, Alanine, Arginine, Histidine, Isoleucine, Leucine, Methionine, Phenylalanine, Proline, Serin?

When using Kabiven, clinicians should observe several safety measures. - Renal function: monitor serum creatinine and urea levels. - Liver function: assess hepatic enzymes as amino acid metabolism may be altered. - Electrolytes: check serum electrolytes regularly. - Glucose control: monitor blood glucose in diabetic patients. - Infusion rate: adjust to avoid fluid overload. - Store at 2-8°C: keep refrigerated, protect from light, do not freeze or shake.

What does Valine, Alanine, Arginine, Histidine, Isoleucine, Leucine, Methionine, Phenylalanine, Proline, Serin interact with?

Kabiven may interact with other intravenous therapies; awareness of potential interactions is essential.

Major Interactions (Avoid): - Co‑administration with high‑dose lipid emulsions may cause precipitation. - Concurrent use with nephrotoxic antibiotics (e.g., aminoglycosides) can increase renal risk.

Moderate Interactions (Monitor Closely): - Simultaneous IV dextrose solutions may affect glucose balance. - Combined electrolyte solutions may require adjustment of electrolyte content. - Use with other nitrogen‑containing parenteral products may lead to excess nitrogen load.

Frequently asked questions

What is Kabiven used for?+
Kabiven is an amino acid solution administered intravenously as part of total parenteral nutrition. It provides essential and non‑essential amino acids to patients who cannot receive nutrition through the gastrointestinal tract, such as those in postoperative, trauma, or intensive care settings.
How does the amino acid mixture in Kabiven work?+
The amino acids in Kabiven are directly available in the bloodstream, serving as building blocks for protein synthesis and supporting nitrogen balance. They also participate in metabolic pathways like gluconeogenesis and neurotransmitter production, helping maintain cellular function when enteral feeding is not possible.
What is the usual dose of Kabiven?+
The dose of Kabiven is individualized. A qualified prescriber determines the volume and rate based on the patient’s weight, clinical condition, and nutritional requirements, following institutional protocols for total parenteral nutrition.
Is Kabiven safe to use during pregnancy or breastfeeding?+
The safety of Kabiven in pregnancy or lactation has not been fully established. Use is generally reserved for situations where the benefits outweigh potential risks, and it should be prescribed by a specialist familiar with maternal‑fetal considerations.
How do I order Kabiven from GNH USA?+
To order Kabiven, submit an enquiry on the product page at gnh-usa.com, specifying the required quantity. GNH USA works with hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including any cold‑chain requirements), and necessary import documentation.
How does Kabiven compare with other parenteral nutrition amino acid products?+
Kabiven offers a comprehensive blend of essential and non‑essential amino acids in a single sterile solution, matching the amino acid profile recommended for adult total parenteral nutrition. Compared with products that provide separate amino acid modules, Kabiven simplifies preparation and reduces the risk of mixing errors, while delivering comparable nutritional support.
What are the storage and handling requirements for Kabiven?+
Kabiven should be stored at 2‑8 °C in a refrigerator, protected from light. Do not freeze or shake the vial. Before use, inspect the solution for particulate matter or discoloration and allow it to reach room temperature if required by the administration protocol.
How is Kabiven administered?+
Kabiven is administered intravenously as a sterile solution for injection. It is typically infused through a central venous catheter or a peripheral line, using an infusion pump to control the rate according to the prescribed total parenteral nutrition regimen.
What are the most serious risks associated with Kabiven?+
Serious risks include anaphylactic reactions, metabolic acidosis, and severe electrolyte disturbances such as hypernatremia. Clinicians should monitor patients closely for signs of allergic response, acid‑base balance, and electrolyte levels throughout the infusion.
Who should not receive Kabiven?+
Kabiven is contraindicated in patients with known hypersensitivity to any of its amino acid components, those with uncontrolled severe electrolyte abnormalities, or individuals for whom total parenteral nutrition is not indicated. Clinical judgment should guide use in patients with severe hepatic or renal impairment.
Information provided on this page is for educational use by procurement and clinical professionals. Always consult a licensed healthcare provider for medical advice and prescribing decisions. GNH USA supplies this product subject to applicable regulatory and licensing requirements.

Product details

Drug
Valine, Alanine, Arginine, Histidine, Isoleucine, Leucine, Methionine, Phenylalanine, Proline, Serin
Route
Intravenous Use
Manufacturer
Fresenius Kabi Ab
Origin
EU

Related products