Europe — EMA
Kabiven Peripheral
GNH USA supplies Kabiven Peripheral (Amino acids), a parenteral nutrition solution for patients unable to receive enteral feeding.
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What is Valine, Alanine, Arginine, Histidine, Isoleucine, Leucine, Methionine, Phenylalanine, Proline, Serin?
Valine, Alanine, Arginine, Histidine, Isoleucine, Leucine, Methionine, Phenylalanine, Proline, Serin, the active ingredients in Kabiven Peripheral, are a parenteral nutrition solution presented as an intravenous solution for intravenous use. It provides essential amino acids to patients who cannot receive enteral feeding.
GNH USA supplies Kabiven Peripheral as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, transplant centres and intensive‑care units worldwide.
What is Valine, Alanine, Arginine, Histidine, Isoleucine, Leucine, Methionine, Phenylalanine, Proline, Serin used for?
Kabiven Peripheral is used in parenteral nutrition to support protein and nitrogen balance in patients unable to receive enteral feeding. - Parenteral nutrition: Provides essential amino acids for patients who cannot receive enteral feeding. - Surgical patients: Helps maintain protein synthesis and nitrogen balance during the peri‑operative period. - Critically ill patients: Supports metabolic needs and prevents catabolism in intensive‑care settings.
What are the side effects of Valine, Alanine, Arginine, Histidine, Isoleucine, Leucine, Methionine, Phenylalanine, Proline, Serin?
Common Side Effects: - Hyperglycemia: Elevated blood glucose levels during infusion. - Electrolyte imbalance: Changes in serum potassium, sodium or calcium. - Infusion site reactions: Redness, pain or swelling at the catheter site. - Mild nausea: Transient feeling of nausea during or after infusion. - Fever: Low‑grade temperature rise. - Increased blood urea nitrogen: Indicative of protein metabolism.
Serious or Rare Side Effects: - Anaphylactic reaction: Severe allergic response requiring immediate medical attention. - Metabolic acidosis: Significant drop in blood pH. - Severe hypernatremia: Critically high sodium levels. - Hepatic dysfunction: Abnormal liver enzyme elevations.
What precautions apply to Valine, Alanine, Arginine, Histidine, Isoleucine, Leucine, Methionine, Phenylalanine, Proline, Serin?
Kabiven Peripheral should be used with careful clinical monitoring. - Renal impairment: Monitor renal function and adjust infusion rate. - Liver disease: Assess hepatic function before initiation. - Electrolyte disturbances: Check serum electrolytes regularly. - Hyperglycemia risk: Monitor blood glucose levels during therapy. - Pregnancy and lactation: Use only if potential benefit outweighs risk. - Store at 2‑8°C: Keep refrigerated, protect from light, do not freeze.
What does Valine, Alanine, Arginine, Histidine, Isoleucine, Leucine, Methionine, Phenylalanine, Proline, Serin interact with?
Kabiven Peripheral may interact with other intravenous therapies. Major Interactions (Avoid): - Concurrent high‑dose amino acid solutions: Risk of amino acid overload. - Calcium‑containing IV solutions: May precipitate when mixed. Moderate Interactions (Monitor Closely): - Loop diuretics: May increase electrolyte loss. - Insulin therapy: May require dose adjustment due to glucose changes. - Renal replacement therapy: May affect amino acid clearance.